Patents by Inventor Hilmar Mildenberger
Hilmar Mildenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5945541Abstract: The present invention relates to agents for protecting crop plants from the phytotoxic side effects of herbicides, which agents contain a compound of the formula I ##STR1## wherein Y denotes C--H or N,the symbols R.sub.1 independently of one another denote alkyl, halo-alkyl, alkoxy, haloalkoxy or halogen,R.sub.2 denotes alkyl or cycloalkyl,X denotes COOR.sub.3, CON(R.sub.4).sub.2, COSR.sub.3, CN or ##STR2## R.sub.3 denotes an alkali metal or alkaline earth metal, hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, or phenylalkyl, it being possible for phenyl to be substituted by halogen, or trialkylsilylalkyl or alkoxyalkyl,the symbols R.sub.4 independently of one another denote H, alkyl or cycloalkyl, which can be substituted, or 2 radicals R.sub.4 together with the N atom linking them form a 4- to 7-membered heterocyclic ring andn denotes 1 to 3, in combination with a herbicide.Type: GrantFiled: December 15, 1994Date of Patent: August 31, 1999Assignee: Hoechst Schering AgrEvo GmbHInventors: Erich Sohn, Hilmar Mildenberger, Klaus Bauer, Hermann Bieringer
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Patent number: 5854288Abstract: The use of compounds of the formula I ##STR1## in which R.sup.1 -R.sup.6, A, B und X have the meaning given in detail in the description, for controlling house dust mites.The miticide has a high miticidal effect against house dust mites of Tyrophagus, Dermatophagoides, Cheyletidae, etc. and is harmless to humans and beasts. It is effective not only in exterminating such house dust mites but also in preventing from them.Type: GrantFiled: August 2, 1996Date of Patent: December 29, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Yoshio Katsuda, Hans-Herbert Schubert, Hilmar Mildenberger, Stefan Schnatterer, Herbert Stark
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Patent number: 5401700Abstract: The present invention relates to agents for protecting crop plants from the phytotoxic side effects of herbicides, which agents contain a compound of the formula ##STR1## wherein Y denotes C--H or N,the symbols R.sub.1 independently of one another denote alkyl, halo-alkyl, alkoxy, haloalkoxy or halogen,R.sub.2 denotes alkyl or cycloalkyl,X denotes COOR.sub.3, CON(R.sub.4).sub.2, COSR.sub.3, CN or ##STR2## R.sub.3 denotes an alkali metal or alkaline earth metal, hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, or phenylalkyl, it being possible for phenyl to be substituted by halogen, or trisalkylsilylalkyl or alkoxyalkyl,the symbols R.sub.4 independently of one another denote H, alkyl or cycloalkyl, which can be substituted, or radicals R.sub.4 together with the N atom linking them form a 4- to 7-membered heterocyclic ring andn denotes 1 to 3,in combination with a herbicide.Type: GrantFiled: July 13, 1992Date of Patent: March 28, 1995Assignee: Hoechst AktiengesellschaftInventors: Erich Sohn, Hilmar Mildenberger, Klaus Bauer, Hermann Bieringer
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Patent number: 5374725Abstract: A compound of formula I or salt thereof can be prepared in a process which comprises reacting a compound of formula II with a compound of formula III: ##STR1## wherein the formulae I-III the radical X is O, ONR.sup.2 or SO.sub.2 NR.sup.2 ; Y is N or CH;R.sup.1 is (subst.) alkyl, (subst.) alkenyl, (subst.) alkynyl, or in case X.dbd.O, also (subst.) phenyl;R.sup.2 is H, alkyl, alkenyl, alkynyl or cycloalkyl,R.sup.3 -R.sup.6 are defined in claim 1;Z is S or NR.sup.8 ; R.sup.7, R.sup.8 are H, alkyl, (subst.) phenyl or (subst.) benzyl, or, in case Z.dbd.NR.sup.8, R.sup.7 and NR.sup.8 are also a 5- to 7-membered heterocycle.Type: GrantFiled: February 22, 1994Date of Patent: December 20, 1994Assignee: Hoechst AktiengesellschaftInventors: Gunter Schlegel, Hilmar Mildenberger
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Patent number: 5208337Abstract: 2-Aminopyrimidines of the formula I ##STR1## in which X and Y are O or S and R.sup.1 and R.sup.2 independently of one another are lower alkyl, alkoxyalkyl or haloalkyl, are obtained by reacting propanediimidates of the formula IIR.sup.1 --X--C(.dbd.NH)--CH.sub.2 --C(.dbd.NH)--Y--R.sup.2 (II)or salts thereof with cyanamide in the presence of a base at pH values above pH 7.Type: GrantFiled: September 13, 1991Date of Patent: May 4, 1993Assignee: Hoechst AktiengesellschaftInventors: Stephen Lachhein, Hilmar Mildenberger
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Patent number: 5153345Abstract: Process for the preparation of compounds of the formula ##STR1## where R is (C.sub.1 -C.sub.4)alkyl, which comprises reacting a compound of the formula II ##STR2## with an alcoholate of the formula IIIMet-OR (III)where Met is Na or K and R has the abovementioned meaning, at temperature from -30.degree. C. to +10.degree. C.Type: GrantFiled: October 18, 1990Date of Patent: October 6, 1992Assignee: Hoechst AktiengesellschaftInventors: Harald Knorr, Hilmar Mildenberger, Hans J. Nestler
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Patent number: 5153355Abstract: A large number of customary processes for separating amino acids fails when very polar hydrophilic amino acids with isoelectric points (IEP) which are close to one another are to be fractionated. Mixtures of L-glutamic acid (IEP=3.24) and L-phosphinothricin (IEP=2.6) produced by enzymatic transaminations of the corresponding .alpha.-keto acid have been difficult to separate to date. The invention relates to a process for separating L-phosphinothricin and L-glutamic acid, which comprises carrying out the separation as liquid/liquid extraction with two non-miscible aqueous phases as phase system, where the phase former contained in the phase system is a combination of at least two different water-soluble polymers or of at least one water-soluble salt and one water-soluble polymer, and the extraction is carried out by multistage countercurrent partition on the van Dijck principle.Type: GrantFiled: August 21, 1991Date of Patent: October 6, 1992Assignee: Hoechst AktiengesellschaftInventors: Hilmar Mildenberger, Harald Knorr, Arno Schulz, Heribert Tetzlaff
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Patent number: 5082949Abstract: Compounds of the formula I ##STR1## in which R denotes halogen, hydroxyl, cyano, nitro, (substituted) alkyl, (substituted) alkoxy, (halo)alkylthio, carboxyl, alkoxycarbonyl; (halo)alkylsulf(inyl) (onyl) or -(onyloxy); (halo)phenyl or (halo)phenoxy; X in the 3- or 5-position denotes a (thio)carboxylic acid--or an optionally heterocyclic radical which is derived therefrom; Y denotes halogen, m denotes the number 0 or 1, and n denotes a number from 0 to 5, have valuable plant growth-regulating properties and are suitable, in addition, as safeners for protecting crop plants against phytotoxic side effects of herbicides.Type: GrantFiled: October 31, 1989Date of Patent: January 21, 1992Assignee: Hoechst AktiengesellschaftInventors: Erich Sohn, Reinhard Handte, Hilmar Mildenberger, Helmut Burstell, Klaus Bauer, Hermann Bieringer
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Patent number: 5013444Abstract: The invention relates to a gentle process for the separation of enol ethers from mixtures containing water-soluble alcohols by extraction, wherein an aqueous solution of a base is used as the extraction agent in a phase ratio of the amounts of the aqueous phase: enol ether/alcohol mixture of at least 0.5:1 and the extraction is carried out in several stages or continuously with a theoretical number of stages of at least two. The process is particularly suitable for separating off enol ethers which readily decompose during distillation.Type: GrantFiled: August 29, 1990Date of Patent: May 7, 1991Assignee: Hoechst AktiengesellschaftInventors: Hilmar Mildenberger, Stephen Lachhein, Siegbert Rittner, Heribert Tetzlaff
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Patent number: 4978774Abstract: Process for the preparation of D(+)-2-(4-acetylphenoxy)-propionic estersPreparation of D(+)-2-(4-acetylphenoxy)-propionic esters of the formula ##STR1## by reacting 4-hydroxyacetophenone with L-halo- or sulfonyloxy-lactic esters in a basic medium at temperatures .ltoreq.50.degree. C.Type: GrantFiled: January 25, 1990Date of Patent: December 18, 1990Assignee: Hoechst AktiengesellschaftInventors: Gunter Schlegel, Hilmar Mildenberger
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Patent number: 4925478Abstract: Compounds of the formula ##STR1## in which R.sub.n denotes hydrogen, halogen or alkyl, Z denotes oxygen or sulfur, R.sup.1 and R.sup.2, independently of one another, denote hydrogen, alkyl, alkoxyalkyl, haloalkyl or phenalkyl, or, together, denote a (optionally substituted) C.sub.2 -C.sub.4 -alkylene bridge, and R.sup.3 denotes hydrogen or alkyl, are effective antidotes for protecting crop plants against phytotoxic side effects of herbicides.Type: GrantFiled: July 21, 1987Date of Patent: May 15, 1990Assignee: Hoechst AktiengesellschaftInventors: Erich Sohn, Reinhard Handte, Hilmar Mildenberger, Klaus Bauer, Hermann Bieringer
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Patent number: 4891057Abstract: Compounds of the formula I ##STR1## in which R denotes halogen, hydroxyl, cyano, nitro, (substituted) alkyl, (substituted) alkoxy, (halo)alkylthio, carboxyl, alkoxycarbonyl; (halo)alkylsulf(inyl)(onyl) or -(onyloxy); (halo)phenyl or (halo)phenoxy; X in the 3- or 5-position denotes a (thio)carboxylic acid--or an optionally heterocyclic radical which is derived therefrom; Y denotes halogen, m denotes the number 0 or 1, and n denotes a number from 0 to 5, have valuable plant growth-regulating properties and are suitable, in addition, as safeners for protecting crop plants against phytotoxic side effects of herbicides.Type: GrantFiled: October 2, 1987Date of Patent: January 2, 1990Assignee: Hoechst AktiengesellschaftInventors: Erich Sohn, Reinhard Handte, Hilmar Mildenberger, Helmut Burstell, Klaus Bauer, Hermann Bieringer
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Patent number: 4889864Abstract: Compounds of the formula (I) ##STR1## in which n denotes a number from 2 to 6, m denotes 1 or 2,R denotes ##STR2## R.sup.1 denotes (substituted) alkyl, (substituted) alkenyl, C.sub.3 -alkynyl, cycloalkyl, cycloalkenyl or an aromatic or heteroaromatic radical, R.sup.2 denotes H or alkyl and Y denotes H, alkyl, phenyl or halophenyl, and the metal-salt complexes thereof have advantageous fungicidal actions and are highly suitable for use in plant protection or in the industrial sector.Type: GrantFiled: December 1, 1987Date of Patent: December 26, 1989Assignee: Hoechst AktiengesellschaftInventors: Heinz Ehrhardt, Hilmar Mildenberger, Thomas Maier, Rainer Schaller, Burkhard Sachse, Peter Braun
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Patent number: 4838931Abstract: 1,2-Disubstituted piperidines of the general formula I ##STR1## in which X denotes oxygen or sulfur; R denotes alkyl, R.sup.1 and R.sup.2 denote hydrogen, alkyl or benzyl, R.sup.3 denotes hydrogen, (substituted) alkyl, (substituted) benzyl or a radical of the formulae ##STR2## Y and X denote S or O; Z denotes S, O or NR.sup.1 ; R.sup.4 denotes hydrogen, (substituted) alkyl, (substituted) phenyl, (substituted) naphthyl or (substituted) pyridyl, A denotes (substituted) phenyl or (substituted) naphthyl and m denotes 0, 1 or 2, possess advantageous herbicidal properties.Type: GrantFiled: January 14, 1987Date of Patent: June 13, 1989Assignee: Hoechst AktiengesellschaftInventors: Rainer Liebl, Michael Frey, Hilmar Mildenberger, Klaus Bauer, Hermann Bieringer
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Patent number: 4814459Abstract: Compounds of the formula ##STR1## in which X denotes O or S; R and R.sup.1 denote H, halogen, alkyl, alkoxy, CN, NO.sub.2 or CF.sub.3 ; R.sup.2 denotes H or alkyl; Y denotes an optionally substituted alkylene or phenylene group and Z denotes a carboxyl, carboxylate, carboxylic acid ester, carboxamide, nitrile or thioamide group, are suitable for reducing the phytotoxicity of herbicides in useful plants.Type: GrantFiled: May 28, 1985Date of Patent: March 21, 1989Assignee: Hoechst AktiengesellschaftInventors: Heinz Boesenberg, Hilmar Mildenberger, Klaus Bauer, Hermann Bieringer
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Patent number: 4808213Abstract: The compounds of the formula I, or salts thereof, ##STR1## in which R.sup.1 and R.sup.2, independently of one another, denote (C.sub.1 -C.sub.4)-alkyl,R.sup.3 denotes halogen, in particular Cl or Br,R.sup.4 denotes hydrogen, Cl, Br or methyl,X denotes O, S or N-R.sup.5, andR.sup.5 denotes hydrogen, (C.sub.2 -C.sub.6)-alkenyl or (C.sub.1 -C.sub.6)-alkyl, where the alkyl group may be up to disubstituted by (C.sub.1 -C.sub.6)-alkoxy or (C.sub.1 -C.sub.3)-dialkylamino, or up to hexasubstituted by halogen,have an excellent plant growth-regulating action in important crops.Type: GrantFiled: August 25, 1987Date of Patent: February 28, 1989Assignee: Hoechst AktiengesellschaftInventors: Roland Schmierer, Hilmar Mildenberger, Helmut Burstell
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Patent number: 4792610Abstract: A highly selective, inexpensive and quantitative process is described for the preparation of 5-phenylsulfinyl-1H-2-(methoxycarbonylamino)-benzimidazole (oxfendazole) through reaction of 5-phenylmercapto-1H-2-(methoxycarbonylamino)-benzimidazole with hydrogen peroxide in the presence of one or more aliphatic C.sub.1 -C.sub.6 -alcohols with addition of a strong, nonoxidizing mineral acid.Type: GrantFiled: July 31, 1987Date of Patent: December 20, 1988Assignee: Hoechst AktiengesellschaftInventors: Stephen Lachhein, Hilmar Mildenberger, Hans-Joachim Ressel
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Patent number: 4786312Abstract: The new compounds of the formula I ##STR1## in which R denotes substituted phenyl,X denotes a radical of the formula --SH, ##STR2## or hydrogen, Y denotes a radical of the formula ##STR3## and the bisulfite adducts, acetals, ketals, thioacetals or thioketals derived from ##STR4## Z denotes O, S or N--R.sup.6 ; m denotes 0, 1 or 2; n denotes 0, 1, 2, 3 or 4 and p denotes 2 or 3,and the salts and quaternization products which are acceptable for agricultural purposes have advantageous plant growth-regulating actions. Processes for the preparation thereof are also described.Type: GrantFiled: April 24, 1987Date of Patent: November 22, 1988Assignee: Hoechst AktiengesellschaftInventors: Roland Schmierer, Hilmar Mildenberger, Helmut Bustell
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Patent number: 4764624Abstract: The compounds of the formula I ##STR1## wherein R denotes (substituted) phenyl, (substituted) cyclohexyl or (substituted) cyclohexenyl,X denotes a radical of the formulae ##STR2## Y denotes a radical of the formulae ##STR3## and the bisulfite adducts, acetals, ketals, thioacetals or thioketals derived from ##STR4## Z denotes O, S or N--R.sup.8, m denotes 0, 1 or 2, n denotes 0, 1, 2, 3, or 4 and p denotes 2 or 3,and their salts and quaternization products which are acceptable for agricultural purposes possess advantageous plant growth-regulating actions.Type: GrantFiled: October 16, 1986Date of Patent: August 16, 1988Assignee: Hoechst AktiengesellschaftInventors: Roland Schmierer, Hilmar Mildenberger, Reinhard Handte, Helmut Burstell
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Patent number: 4755213Abstract: The compounds of the formula (I) ##STR1## in which R.sup.1 denotes (C.sub.1 -C.sub.3)alkyl and R.sup.2 denotes H, methyl or halogen, and salts thereof have excellent actions as plant growth regulators, in particular in rice crops.Type: GrantFiled: March 10, 1987Date of Patent: July 5, 1988Assignee: Hoechst AktiengesellschaftInventors: Roland Schmierer, Reinhard Handte, Hilmar Mildenberger, Helmut Burstell