Patents by Inventor Hina N. Syed

Hina N. Syed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-denaturing lysis reagent
    Patent number: 8697365
    Abstract: The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent includes a glycol and an alcohol. Other aspects of the invention include related immunoassays and test kits.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: April 15, 2014
    Assignee: Abbott Laboratories
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • Diagnostic test for the detection of a molecule or drug in whole blood
    Patent number: 8440416
    Abstract: The invention provides methods of preparing a test sample for use in an assay for detecting an analyte bound by an intracellular ligand. The methods typically involve contacting the test sample with an assay reagent comprising: a lysis reagent; and a protease that has proteolytic activity for said intracellular ligand; to form a mixture compatible for use in an immunoassay without subsequent extraction steps. Other aspects of the invention include related immunoassays and test kits.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: May 14, 2013
    Assignee: Abbott Laboratories
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • Neutrophil gelatinase-associated lipocalin (NGAL) protein isoforms enriched from urine and recombinant chinese hamster ovary (CHO) cells and related compositions, antibodies, and methods of enrichment, analysis and use
    Patent number: 8394606
    Abstract: A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: March 12, 2013
    Assignee: Abbott Laboratories
    Inventors: Salman Ali, Ryan M. Bonn, Frank C. Grenier, Tracey D. Rae, Kevin R. Rupprecht, Hina N. Syed, Bailin Tu, Joan D. Tyner, Ryan F. Workman
  • Diagnostic Test For The Detection Of A Molecule Or Drug In Whole Blood
    Publication number: 20120288875
    Abstract: The invention provides methods of preparing a test sample for use in an assay for detecting an analyte bound by an intracellular ligand. The methods typically involve contacting the test sample with an assay reagent comprising: a lysis reagent; and a protease that has proteolytic activity for said intracellular ligand; to form a mixture compatible for use in an immunoassay without subsequent extraction steps. Other aspects of the invention include related immunoassays and test kits.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 15, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • Diagnostic test for the detection of a molecule or drug in whole blood
    Patent number: 8221986
    Abstract: The invention provides methods of preparing a test sample for use in an assay for detecting an analyte bound by an intracellular ligand. The methods typically involve contacting the test sample with an assay reagent comprising: a lysis reagent; and a protease that has proteolytic activity for said intracellular ligand; to form a mixture compatible for use in an immunoassay without subsequent extraction steps. Other aspects of the invention include related immunoassays and test kits.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: July 17, 2012
    Assignee: Abbott Laboratories
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • NON-DENATURING LYSIS REAGENT
    Publication number: 20110171662
    Abstract: The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent includes a glycol and an alcohol. Other aspects of the invention include related immunoassays and test kits.
    Type: Application
    Filed: March 24, 2011
    Publication date: July 14, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • Non-denaturing lysis reagent
    Patent number: 7914999
    Abstract: The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent includes a glycol and an alcohol. Other aspects of the invention include related immunoassays and test kits.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: March 29, 2011
    Assignee: Abbott Laboratories
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • Dual Variable Domain Immunoglobulins and Uses Thereof
    Publication number: 20110008766
    Abstract: Engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: April 30, 2010
    Publication date: January 13, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Tariq Ghayur, Junjian Liu, Susan E. Brophy, Sushil G. Devare, Frank C. Grenier, Jeffrey A. Moore, Qiaoqiao Ruan, Sergey Y. Tetin, Jennifer M. Steinhaus, Salman Ali, Hina N. Syed
  • NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL) PROTEIN ISOFORMS ENRICHED FROM URINE AND RECOMBINANT CHINESE HAMSTER OVARY (CHO) CELLS AND RELATED COMPOSITIONS, ANTIBODIES, AND METHODS OF ENRICHMENT, ANALYSIS AND USE
    Publication number: 20100116662
    Abstract: A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 13, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Salman Ali, Ryan M. Bonn, Frank C. Grenier, Tracey D. Rae, Kevin R. Rupprecht, Hina N. Syed, Bailin Tu, Joan D. Tyner, Ryan F. Workman
  • Diagnostic Test For The Detection Of A Molecule Or Drug In Whole Blood
    Publication number: 20090325193
    Abstract: The invention provides methods of preparing a test sample for use in an assay for detecting an analyte bound by an intracellular ligand. The methods typically involve contacting the test sample with an assay reagent comprising: a lysis reagent; and a protease that has proteolytic activity for said intracellular ligand; to form a mixture compatible for use in an immunoassay without subsequent extraction steps. Other aspects of the invention include related immunoassays and test kits.
    Type: Application
    Filed: June 25, 2009
    Publication date: December 31, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali
  • NON-DENATURING LYSIS REAGENT
    Publication number: 20080160499
    Abstract: The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture suitable for use in automated pipetting systems without the need for a centrifugation step. The lysis reagent includes a glycol and an alcohol. Other aspects of the invention include related immunoassays and test kits.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 3, 2008
    Inventors: Frank C. Grenier, Ryan F. Workman, Hina N. Syed, Salman Ali