Patents by Inventor Hira V. Thapliyal
Hira V. Thapliyal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200390541Abstract: A personalized prosthetic valve for implantation at a native valve treatment site includes a self-expanding mesh and a plurality of valve leaflets coupled to the mesh. The mesh may be delivered to the native valve in a collapsed configuration, and in an expanded configuration the mesh engages the native valve. The mesh in the expanded configuration is also personalized to match the treatment site, such that the outer mesh surface substantially matches the treatment site shape and size. The self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough. In the open configuration, blood passes through the prosthetic valve, and in the closed configuration, the plurality of leaflets are closer together and blood is prevented from flowing upstream through the prosthetic valve.Type: ApplicationFiled: August 26, 2020Publication date: December 17, 2020Inventor: Hira V. Thapliyal
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Patent number: 10850133Abstract: Methods for ablating tissue in a patient having atrial fibrillation comprise advancing an elongate flexible shaft through a patient's vasculature into a chamber of a heart. The elongate flexible shaft has an energy source and a sensor. Tissue in the heart is scanned with the sensor and data about the tissue is captured. The captured data is grouped into one of a plurality of tissue classifications and an anatomical map of the tissue showing the grouped data is displayed. At least a portion of the tissue is ablated so as to form a conduction block that blocks aberrant electrical pathways in the heart. The ablated tissue is grouped into one or more predefined tissue classifications during or prior to the ablation.Type: GrantFiled: September 5, 2017Date of Patent: December 1, 2020Assignee: Auris Health, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Publication number: 20200214867Abstract: A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh and/or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration is oversized relative to the treatment site and configured to engage the personalized prosthesis with the treatment site. The self-expanding mesh is configured to reduce in one or more dimensions in response to being constrained in the one or more dimensions, such that the mesh in the expanded configuration self-adjusts to the treatment site without buckling of the mesh. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.Type: ApplicationFiled: January 9, 2020Publication date: July 9, 2020Inventor: Hira V Thapliyal
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Publication number: 20200188144Abstract: A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Inventor: Hira V Thapliyal
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Publication number: 20200155192Abstract: An ablation system for treating atrial fibrillation in a patient comprises an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.Type: ApplicationFiled: June 13, 2019Publication date: May 21, 2020Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Patent number: 10617539Abstract: A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.Type: GrantFiled: September 22, 2017Date of Patent: April 14, 2020Assignee: AneuMed, Inc.Inventor: Hira V. Thapliyal
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Patent number: 10575975Abstract: A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh and/or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration is oversized relative to the treatment site and configured to engage the personalized prosthesis with the treatment site. The self-expanding mesh is configured to reduce in one or more dimensions in response to being constrained in the one or more dimensions, such that the mesh in the expanded configuration self-adjusts to the treatment site without buckling of the mesh. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.Type: GrantFiled: April 22, 2016Date of Patent: March 3, 2020Assignee: AneuMed, Inc.Inventor: Hira V Thapliyal
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Publication number: 20190314052Abstract: A cardiac ablation method including the following steps: inserting a treatment catheter into an atrium of a heart, the treatment catheter including an ultrasound emitter; positioning the ultrasound emitter to face heart tissue within the left atrium outside of a pulmonary vein; emitting ultrasound energy from the ultrasound emitter while rotating the ultrasound emitter about a rotation axis; and ablating heart tissue with the ultrasound energy to form a lesion outside of a pulmonary vein.Type: ApplicationFiled: June 5, 2019Publication date: October 17, 2019Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Patent number: 10368891Abstract: An ablation system for treating atrial fibrillation in a patient comprises an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.Type: GrantFiled: September 28, 2012Date of Patent: August 6, 2019Assignee: VytronUS, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Patent number: 10363057Abstract: An ablation system for treating atrial fibrillation in a patient including an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.Type: GrantFiled: July 17, 2009Date of Patent: July 30, 2019Assignee: VytronUS, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Patent number: 10349966Abstract: A cardiac ablation method including the following steps: inserting a treatment catheter into an atrium of a heart, the treatment catheter including an ultrasound emitter; positioning the ultrasound emitter to face heart tissue within the left atrium outside of a pulmonary vein; emitting ultrasound energy from the ultrasound emitter while rotating the ultrasound emitter about a rotation axis; and ablating heart tissue with the ultrasound energy to form a lesion outside of a pulmonary vein.Type: GrantFiled: May 25, 2018Date of Patent: July 16, 2019Assignee: VytronUS, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Publication number: 20190209301Abstract: A personalized prosthetic valve for implantation at a native valve treatment site includes a self-expanding mesh and a plurality of valve leaflets coupled to the mesh. The mesh may be delivered to the native valve in a collapsed configuration, and in an expanded configuration the mesh engages the native valve. The mesh in the expanded configuration is also personalized to match the treatment site, such that the outer mesh surface substantially matches the treatment site shape and size. The self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough. In the open configuration, blood passes through the prosthetic valve, and in the closed configuration, the plurality of leaflets are closer together and blood is prevented from flowing upstream through the prosthetic valve.Type: ApplicationFiled: March 18, 2019Publication date: July 11, 2019Inventor: Hira V Thapliyal
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Publication number: 20190159800Abstract: A tissue ablation system for treating fibrillation in a patient comprises a steerable interventional catheter having an energy source that emits a beam of energy to ablate tissue thereby creating a conduction block for aberrant electrical pathways. The system also includes a handle disposed near a proximal end of the interventional catheter and has an actuation mechanism for steering the interventional catheter. A console allows the system to be controlled and provides power to the system, and a display pod is electrically coupled with the console. The display pod has a display panel to display system information to a user and allows the user to control the system. A catheter pod is releasably coupled with the handle electrically and mechanically, and also electrically coupled with the display pod.Type: ApplicationFiled: February 1, 2019Publication date: May 30, 2019Inventors: Hira V. THAPLIYAL, David A. GALLUP, James W. ARENSON, Robert BROMMER
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Patent number: 10292815Abstract: A personalized prosthetic valve for implantation at a native valve treatment site includes a self-expanding mesh and a plurality of valve leaflets coupled to the mesh. The mesh may be delivered to the native valve in a collapsed configuration, and in an expanded configuration the mesh engages the native valve. The mesh in the expanded configuration is also personalized to match the treatment site, such that the outer mesh surface substantially matches the treatment site shape and size. The self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough. In the open configuration, blood passes through the prosthetic valve, and in the closed configuration, the plurality of leaflets are closer together and blood is prevented from flowing upstream through the prosthetic valve.Type: GrantFiled: June 29, 2017Date of Patent: May 21, 2019Assignee: AneuMed, Inc.Inventor: Hira V. Thapliyal
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Publication number: 20190060677Abstract: Echo-anatomically mapping tissue includes advancing a catheter having an ultrasound transducer toward tissue. A console adjacent the proximal end of the catheter controls catheter movement, and the ultrasound transducer senses tissue. First and second regions of the tissue are ultrasonically sensed while moving the ultrasound transducer along first, and second sensing patterns, respectively. A first 3-dimensional surface map of the first region, and a second 3-dimensional surface map of the second region are generated. The 3-dimensional surface maps are combined to form a combined surface map. Anatomical features may be identified in the first or second sensed regions. The tissue may be ultrasonically ablated while moving the ultrasound transducer along a first ablation path. The first ablation path may form a lesion around the identified anatomical features, and may be selected from a catalog of ablation paths or it may be prescribed by a physician.Type: ApplicationFiled: October 25, 2018Publication date: February 28, 2019Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Patent number: 10154831Abstract: A method for creating a transmural lesion in tissue includes positioning a distal portion of a catheter near the tissue, where an ultrasound transducer is attached to the distal portion and is operatively coupled to a console and processor. The tissue is imaged by energizing the ultrasound transducer at a first power level to produce an ultrasound beam, where the imaging determines a thickness of the tissue, and a gap distance between the ultrasound transducer and the tissue. The tissue is ablated by energizing the ultrasound transducer at a second power level to produce the ultrasound beam. Energy delivered to the tissue during the ablating is controlled, using the processor, where the processor adjusts a speed of the ultrasound beam moving across the tissue based on the thickness and gap distance, to create the transmural lesion.Type: GrantFiled: August 4, 2017Date of Patent: December 18, 2018Assignee: VytronUS, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson, John Paul Mohr, III, Tim Proulx, Robert A. Brommer
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Publication number: 20180271554Abstract: A cardiac ablation method including the following steps: inserting a treatment catheter into an atrium of a heart, the treatment catheter including an ultrasound emitter; positioning the ultrasound emitter to face heart tissue within the left atrium outside of a pulmonary vein; emitting ultrasound energy from the ultrasound emitter while rotating the ultrasound emitter about a rotation axis; and ablating heart tissue with the ultrasound energy to form a lesion outside of a pulmonary vein.Type: ApplicationFiled: May 25, 2018Publication date: September 27, 2018Inventors: Hira V. THAPLIYAL, David A. Gallup, James W. ARENSON
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Patent number: 10052121Abstract: A cardiac ablation method including the following steps: inserting a treatment catheter into an atrium of a heart, the treatment catheter including an ultrasound emitter; positioning the ultrasound emitter to face heart tissue within the left atrium outside of a pulmonary vein; emitting ultrasound energy from the ultrasound emitter while rotating the ultrasound emitter about a rotation axis; and ablating heart tissue with the ultrasound energy to form a lesion outside of a pulmonary vein.Type: GrantFiled: July 20, 2017Date of Patent: August 21, 2018Assignee: Vytronus, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson
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Publication number: 20180126193Abstract: Methods for ablating tissue in a patient having atrial fibrillation comprise advancing an elongate flexible shaft through a patient's vasculature into a chamber of a heart. The elongate flexible shaft has an energy source and a sensor. Tissue in the heart is scanned with the sensor and data about the tissue is captured. The captured data is grouped into one of a plurality of tissue classifications and an anatomical map of the tissue showing the grouped data is displayed. At least a portion of the tissue is ablated so as to form a conduction block that blocks aberrant electrical pathways in the heart. The ablated tissue is grouped into one or more predefined tissue classifications during or prior to the ablation.Type: ApplicationFiled: September 5, 2017Publication date: May 10, 2018Inventors: Hira V. THAPLIYAL, David A. GALLUP, James W. ARENSON
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Patent number: 9907983Abstract: A tissue ablation method for treating atrial fibrillation in a patient comprises locating an ostium of a pulmonary vein and positioning an interventional catheter adjacent the ostium. The interventional catheter has an energy source. Collateral tissue adjacent the ostium is located and tissue around the ostium is ablated with energy from the energy source so as to form a contiguous lesion circumscribing the ostium. The lesion blocks aberrant electrical pathways in the tissue so as to reduce or eliminate the atrial fibrillation. The ablating is modified so as to avoid ablating or otherwise damaging the collateral tissue.Type: GrantFiled: September 28, 2012Date of Patent: March 6, 2018Assignee: VytronUS, Inc.Inventors: Hira V. Thapliyal, David A. Gallup, James W. Arenson