Abstract: A Bayesian image processing method and apparatus take into account supplementary source information previously ignored by most likely source distribution techniques and produce highly accurate results.

Abstract: A combined experimental and analytical method and apparatus for determining radioisotope tissue concentrations from a series of two-dimensional scans is proposed. Each two-dimensional scan is identified as the output from the unknown three-dimensional radioisotope tissue distribution as appropriately modified or convoluted by a series of independently determined depth-dependent point source response functions of the system. A direct non-local method of iterative deconvolution which is relatively insensitive to random noise is used to determine the unknown tissue concentration from the measured scan data and the known point source response characteristics of the system. The series of depth-dependent two-dimensional scans can be parallel to each other or at a series of arbitrary angles of orientation to the unknown source distribution.