Patents by Inventor Hiranthi Jayasuriya

Hiranthi Jayasuriya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotic compound
    Patent number: 7807445
    Abstract: Fermentation of a nutrient medium with a eubacterium Streptomyces sp. yields a novel antibacterial compound of structural formula (I).
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: October 5, 2010
    Assignees: Merck Sharp and Dohme de Espana, S.A., Merck Sharp & Dohme Corp.
    Inventors: Angela Basilio, Olga Genilloud, Hiranthi Jayasuriya, Ignacio Gonzalez, Sheo B. Singh, Oscar Salazar, Jun Wang
  • Antibiotic Compound
    Publication number: 20100144879
    Abstract: Fermentation of a nutrient medium with a eubacterium Streptomyces sp. yields a novel antibacterial compound of structural formula (I).
    Type: Application
    Filed: May 20, 2005
    Publication date: June 10, 2010
    Inventors: Angela Basilio, Olga Genilloud, Hiranthi Jayasuriya, Ignacio Gonzalez, Sheo B. Singh, Oscar Salazar, Jun Wang
  • Antibiotic Compound
    Publication number: 20080096856
    Abstract: Fermentation of a nutrient medium with a Nocardia spp. yields a novel broad spectrum antibiotic compound of structural formula (I) or a pharmaceutically acceptable salt, ester, enantiomer, diasteriomer or mixture.
    Type: Application
    Filed: September 16, 2005
    Publication date: April 24, 2008
    Applicant: MERCK & CO., LTD.
    Inventors: John Barrett, Kithsiri Herath, Hiranthi Jayasuriya, Prakash Masurekar, John Ondeyka, Sheo Singh, Chaowei Zhang
  • HIV integrase inhibitors
    Patent number: 6541515
    Abstract: Compounds useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines are described. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described. The culture Cytospora sp. MF 6608 (ATCC PTA-1691) is also disclosed, as well as processes for making a compound of the present invention employing the culture.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: April 1, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Sheo Bux Singh, Hiranthi Jayasuriya, Ziqiang Guan, Keith C. Silverman, Russell B. Lingham, Anne W. Dombrowski, Daria J. Hazuda, Jon D. Polishook
  • HIV integrase inhibitors
    Publication number: 20020045658
    Abstract: Compounds useful in the inhibition of HIV integrase, the prevention or treatment of infection by HV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines are described. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described. The culture Cytospora sp. MF 6608 (ATCC PTA-1691) is also disclosed, as well as processes for making a compound of the present invention employing the culture.
    Type: Application
    Filed: August 9, 2001
    Publication date: April 18, 2002
    Inventors: Sheo Bux Singh, Hiranthi Jayasuriya, Ziqiang Guan, Keith C. Silverman, Russell B. Lingham, Anne W. Dombrowski, Daria J. Hazuda, Jon D. Polishook
  • Inhibitors of farnesyl-protein transferase
    Patent number: 5703067
    Abstract: The present invention is directed to steroidal or terpenoidal compounds which inhibit farnesyl-protein transferase (FPTase). The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: December 30, 1997
    Assignee: Merck & Co., Inc.
    Inventors: Hiranthi Jayasuriya, Russell B. Lingham, Fernando Pelaez, Manuel Sanchez, Keith C. Silverman, Sheo Bux Singh, Deborah L. Zink