Patents by Inventor Hirdesh Uppal

Hirdesh Uppal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer
    Patent number: 11952634
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: April 9, 2024
    Assignee: Medivation Prostate Therapeutics LLC
    Inventors: Amy Christian Peterson, Hirdesh Uppal
  • METHOD FOR PREDICTING RESPONSE TO BREAST CANCER THERAPEUTIC AGENTS AND METHOD OF TREATMENT OF BREAST CANCER
    Publication number: 20220056541
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Application
    Filed: November 10, 2021
    Publication date: February 24, 2022
    Applicant: Medivation Prostate Therapeutics LLC
    Inventors: Amy Christian PETERSON, Hirdesh UPPAL
  • Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer
    Patent number: 11186876
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: November 30, 2021
    Assignee: Medivation Prostate Therapeutics LLC
    Inventors: Amy Christian Peterson, Hirdesh Uppal
  • METHOD FOR PREDICTING RESPONSE TO BREAST CANCER THERAPEUTIC AGENTS AND METHOD OF TREATMENT OF BREAST CANCER
    Publication number: 20190169697
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Application
    Filed: December 10, 2018
    Publication date: June 6, 2019
    Inventors: Amy Christian PETERSON, Hirdesh UPPAL
  • Method for predicting response to breast cancer therapeutic agents and method of treatment of breast cancer
    Patent number: 10196693
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: February 5, 2019
    Assignee: MEDIVATION PROSTATE THERAPEUTICS LLC
    Inventors: Amy Christian Peterson, Hirdesh Uppal
  • COMPOSITIONS AND METHODS OF OBTAINING AND USING ENDODERM AND HEPATOCYTE CELLS
    Publication number: 20170002313
    Abstract: The invention provides for efficient methods for generating populations of endoderm cells and/or differentiated cells derived from endoderm cells (e.g., hepatic cells, pancreatic precursor cells, pancreatic cells, intestinal progenitor cells, intestinal cells, lung progenitor cells, lung cells, etc.). Also provided are compositions of endoderm cells and differentiated cells derived from endoderm cells (e.g., hepatic cells, pancreatic precursor cells, pancreatic cells, intestinal progenitor cells, intestinal cells, lung progenitor cells, lung cells, etc.) and methods of using such cells.
    Type: Application
    Filed: May 21, 2013
    Publication date: January 5, 2017
    Inventors: Estelle Doudement, Hirdesh Uppal
  • METHOD FOR PREDICTING RESPONSE TO BREAST CANCER THERAPEUTIC AGENTS AND METHOD OF TREATMENT OF BREAST CANCER
    Publication number: 20160168646
    Abstract: Methods for treating triple negative breast cancer with an androgen receptor inhibitor are provided, as well as methods for screening for the likelihood of the effectiveness of such treatment.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 16, 2016
    Inventors: Amy Christian Peterson, Hirdesh Uppal
  • METHODS AND COMPOSITIONS FOR PRODUCING INDUCED HEPATOCYTES
    Publication number: 20150376570
    Abstract: The present invention relates to methods and compositions for use in generating induced hepatocytes by reprogramming non-hepatocyte cells.
    Type: Application
    Filed: April 2, 2015
    Publication date: December 31, 2015
    Applicant: GENENTECH, INC.
    Inventors: Kamen P. Simeonov, Hirdesh Uppal
  • METHODS AND COMPOSITIONS FOR PRODUCING INDUCED HEPATOCYTES
    Publication number: 20140087416
    Abstract: The present invention relates to methods and compositions for use in generating induced hepatocytes by reprogramming non-hepatocyte cells.
    Type: Application
    Filed: September 6, 2013
    Publication date: March 27, 2014
    Applicant: Genentech, Inc.
    Inventors: Kamen P. Simeonov, Hirdesh Uppal
  • ASSAYS TO PREDICT CARDIOTOXICITY
    Publication number: 20110287437
    Abstract: The likelihood that a compound will exhibit cardiotoxicity in vivo can be predicted using a model of in vitro assays performed on primary human cardiomyocytes.
    Type: Application
    Filed: May 20, 2010
    Publication date: November 24, 2011
    Inventors: Hans Marcus Ludwig Bitter, Kyle Louis Kolaja, Preeti Dhawan, Hirdesh Uppal, Rama Rajaraja Varma
  • USE OF PRIMARY HUMAN CARDIOMYOCYTES
    Publication number: 20110212480
    Abstract: The present invention provides for the use of primary human cardiomyocytes for the testing of agents that have cardiotoxic effects and other modulatory effects on the heart.
    Type: Application
    Filed: February 26, 2010
    Publication date: September 1, 2011
    Inventors: Kyle Louis Kolaja, Preeti Dhawan, Hirdesh Uppal
  • PREDICTION OF CARDIOTOXICITY
    Publication number: 20110212461
    Abstract: The likelihood that a compound will exhibit cardiotoxicity in an in vitro or in vivo assay predicted by the ability of the compound to inhibit at least one kinase from a selected group.
    Type: Application
    Filed: February 26, 2010
    Publication date: September 1, 2011
    Inventors: Hans Marcus Ludwig Bitter, Kyle Louis Kolaja, Preeti Dhawan, Hirdesh Uppal, Nina Gonzaludo
  • Prediction of bone marrow toxicity
    Publication number: 20090208991
    Abstract: The likelihood that a compound will exhibit bone marrow toxicity in an in vivo assay predicted by the ability of the compound to inhibit at least eight kinases from a selected group.
    Type: Application
    Filed: February 12, 2009
    Publication date: August 20, 2009
    Inventors: Hans Marcus Ludwig Bitter, David Michael Goldstein, Kyle Louis Kolaja, Henry Lin, Andrew James Olaharski, Hirdesh Uppal