Patents by Inventor Hiroaki Hagiwara

Hiroaki Hagiwara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220298613
    Abstract: A pressed powder material according to embodiments is a pressed powder material including first magnetic metal particles having a first magnetic metal phase containing Fe and Co; and second magnetic metal particles having a second magnetic metal phase containing Fe, in which when the amounts of Co with respect to the total amounts of Fe and Co of the first and second magnetic metal particles are designated as Co1 and Co2, respectively, the ratio of Co2 to Co1 (Co2/Co1) is from 0 to 0.5, the average value of the ratio of the major axis to the minor axis is 2 or greater for the first magnetic metal particles and 1 or greater for the second magnetic metal particles, the second magnetic metal particles are present between the particles of the first magnetic metal particles, and the average value of the major axis of the second magnetic metal particles is equal to or longer than the average value of the major axis of the first magnetic metal particles.
    Type: Application
    Filed: September 3, 2021
    Publication date: September 22, 2022
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventors: Masaya Hagiwara, Tomohiro Suetsuna, Naoyuki Sanada, Hiroaki Kinouchi
  • Publication number: 20220251171
    Abstract: The present invention relates to novel fragments of apolipoprotein E (ApoE). These ApoE fragments have a variety of uses including as components of vaccine compositions, particularly vaccines for the prevention or treatment of neurological disorders such as Alzheimer's disease. The ApoE fragments may also be used in screening methods and methods of detection.
    Type: Application
    Filed: June 25, 2020
    Publication date: August 11, 2022
    Inventors: Hiroaki Hagiwara, Kanta Horie, Kunihiko Kanatsu, Yasuharu Ishihara, Yasuaki Goto, Toru Oki, Masafumi Tsuboi, Charlotte Sahlin, Maria Eriksson, Christer Möller
  • Patent number: 11388885
    Abstract: A rearing cage unit includes an animal residential area defined by a floor, a ceiling, and a wall; an excrement collection area adjacent to the animal residential area; and an excretion sheet in the excrement collection area to receive excrement of the animal. At least one of the floor and the wall is made of a material including resin, and has an excretion hole to allow the excrement in the animal residential area to be discharged to the excrement collection area, and the excretion hole has a size that prevents four feet of the animal from entering the excretion hole. The excretion sheet faces the excretion hole.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: July 19, 2022
    Assignees: MITSUBISHI HEAVY INDUSTRIES, LTD., JAPAN AEROSPACE EXPLORATION AGENCY
    Inventors: Toshimasa Ochiai, Makoto Ohira, Yusuke Hagiwara, Hiroaki Kodama, Hirochika Murase, Masaki Shirakawa, Dai Shiba, Hiroyasu Mizuno, Akane Yumoto
  • Patent number: 9453000
    Abstract: Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by A?, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: September 27, 2016
    Assignee: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Teiji Kimura, Noritaka Kitazawa, Toshihiko Kaneko, Nobuaki Sato, Koki Kawano, Koichi Ito, Mamoru Takaishi, Takeo Sasaki, Yu Yoshida, Toshiyuki Uemura, Takashi Doko, Daisuke Shinmyo, Daiju Hasegawa, Takehiko Miyagawa, Hiroaki Hagiwara
  • Patent number: 9118180
    Abstract: An input protection circuit includes: a first transistor of a field-effect type coupled in series between an input terminal and an electronic circuit, the input terminal receiving an input voltage, the electronic circuit receiving an input voltage, the first transistor switching to an off-state in a case where the input voltage is higher than a positive power supply voltage of the electronic circuit; a second transistor of a field-effect type coupled in series between the first transistor and the electronic circuit, the second transistor switching to an off-state in a case where the input voltage is lower than the negative power supply voltage of the electronic circuit; and a voltage control circuit configured to maintain gate-source voltages of the first transistor and the second transistor as voltages within a power supply voltage range of the electronic circuit based on the input voltage.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: August 25, 2015
    Assignee: YOKOGAWA ELECTRIC CORPORATION
    Inventors: Kazuhide Yasuda, Hiroaki Hagiwara
  • Patent number: 8541321
    Abstract: A copolymerized polyether polyamide resin for coating on or for impregnation to a woven or knitted fabric, wherein elongation and elastic modulus of the copolymerized polyether polyamide resin are not less than 1000% and not more than 15 MPa, respectively. The copolymerized polyether polyamide resin has a constitution wherein said copolymerized polyether polyamide resin is such that a soft segment comprising a polyether polyamide constituted from a polyether diamine compound and a dicarboxylic acid compound is bonded to a hard segment comprising a polyamide constituted from an aminocarboxylic acid compound and/or a lactam compound.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: September 24, 2013
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Hiroaki Hagiwara, Kenichiro Kano, Gaku Maruyama, Takahiro Hattori, Takashi Tsuruta
  • Publication number: 20130229740
    Abstract: An input protection circuit includes: a first transistor of a field-effect type coupled in series between an input terminal and an electronic circuit, the input terminal receiving an input voltage, the electronic circuit receiving an input voltage, the first transistor switching to an off-state in a case where the input voltage is higher than a positive power supply voltage of the electronic circuit; a second transistor of a field-effect type coupled in series between the first transistor and the electronic circuit, the second transistor switching to an off-state in a case where the input voltage is lower than the negative power supply voltage of the electronic circuit; and a voltage control circuit configured to maintain gate-source voltages of the first transistor and the second transistor as voltages within a power supply voltage range of the electronic circuit based on the input voltage.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 5, 2013
    Applicant: YOKOGAWA ELECTRIC CORPORATION
    Inventors: Kazuhide YASUDA, Hiroaki HAGIWARA
  • Patent number: 8048878
    Abstract: The present invention relates to a novel two cyclic cinnamide compound and a pharmaceutical agent comprising the compound as an active ingredient. The two cyclic cinnamide compound represented by the general formula (I): wherein represents a single bond or a double bond; Ar1 represents a phenyl group or pyridinyl group that may be substituted with 1 to 3 substituents; R1 and R2 each represent a C1-6 alkyl group, a hydroxyl group, or the like; Z1 represents a methylene group or vinylene group, which may be substituted with 1 or 2 substituents selected from Substituent Group A1, an oxygen atom, or an imino group that may be substituted with a substituent selected from Substituent Group A1; and p, q, and r each represent an integer of 0 to 2, which has an effect of reducing A?40 and A?42 production, and thus is particularly useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by A? such as Alzheimer's disease or Down's syndrome.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: November 1, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Koki Kawano, Eriko Doi, Noritaka Kitazawa, Mamoru Takaishi, Koichi Ito, Toshihiko Kaneko, Takeo Sasaki, Takehiko Miyagawa, Hiroaki Hagiwara, Yu Yoshida
  • Patent number: 8008293
    Abstract: The present invention relates to a compound represented by formula (I): wherein R1 represents a C1-3 alkyl group, R2 represents a hydrogen atom or a C1-3 alkyl group, Ar represents a phenyl group or the like which may be substituted with 1 to 3 substituents, X represents an oxygen atom or the like, n and m are the same or different and integers of 0 to 2, or a pharmacologically acceptable salt, and use thereof as a medicament.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: August 30, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Koki Kawano, Eriko Doi, Noritaka Kitazawa, Mamoru Takaishi, Koichi Ito, Toshihiko Kaneko, Takeo Sasaki, Nobuaki Sato, Takehiko Miyagawa, Hiroaki Hagiwara
  • Patent number: 7994076
    Abstract: A fabric for an airbag includes a synthetic fiber woven fabric in which at least one side thereof is coated with a synthetic resin. A range of 0.1 to 10 g/m2 of the synthetic resin is adhered to the synthetic fiber woven fabric having a cover factor of less than 2000 and a FR value of 55% or more. Air permeability of the fabric under a pressure difference of 100 kPa after adhesion is 0.01 to 1.00 L/cm2/min. The synthetic resin can be a polyamide-based resin having a soft segment comprising a polyol with a number average molecular weight of 100 to 5000.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: August 9, 2011
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Kenichiro Kano, Takashi Tsuruta, Hideo Isoda, Hiroaki Hagiwara, Gaku Maruyama, Takahiro Hattori
  • Patent number: 7985702
    Abstract: A woven fabric for an airbag includes a synthetic fiber woven fabric having a cover factor of 2000 to 2500 in which at least one side thereof is coated with a synthetic resin. Air permeability of the woven fabric under a pressure difference of 100 kPa is 0.01 to 1.00 L/cm2/min. A resin film is present at an upper part of a single yarn at a thickness of 2 ?m or less on a central cross section of a weaving yarn part. A resin film is present at an upper part of a single yarn at a thickness of 2 to 30 ?m on a cross section at a border between weaving yarn parts. The synthetic resin can be a polyamide-based resin that includes a polyether compound of a number average molecular weight of 100 to 5000 as a soft segment.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: July 26, 2011
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Kenichiro Kano, Takashi Tsuruta, Mamoru Kitamura, Hideo Isoda, Hiroaki Hagiwara, Gaku Maruyama, Takahiro Hattori
  • Patent number: 7973033
    Abstract: The present invention provides a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that may be substituted with a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, which is effective as a therapeutic or prophylactic agent for a disease caused by A?.
    Type: Grant
    Filed: January 12, 2011
    Date of Patent: July 5, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Noritaka Kitazawa, Toshihiko Kaneko, Nobuaki Sato, Koki Kawano, Koichi Ito, Eriko Doi, Mamoru Takaishi, Takeo Sasaki, Takehiko Miyagawa, Hiroaki Hagiwara, Takashi Doko
  • Publication number: 20110112138
    Abstract: The present invention provides a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that may be substituted with a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, which is effective as a therapeutic or prophylactic agent for a disease caused by A?.
    Type: Application
    Filed: January 12, 2011
    Publication date: May 12, 2011
    Inventors: Teiji KIMURA, Noritaka KITAZAWA, Toshihiko KANEKO, Nobuaki SATO, Koki KAWANO, Koichi ITO, Eriko DOI, Mamoru TAKAISHI, Takeo SASAKI, Takehiko MIYAGAWA, Hiroaki HAGIWARA, Takashi DOKO
  • Patent number: 7935815
    Abstract: A compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group or the like which may be substituted with a C1-6 alkyl group, Ar2 represents a phenyl group or the like which may be substituted with a C1-6 alkoxy group, X1 represents a double bond or the like and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, is effective as a therapeutic or prophylactic agent for a disease caused by A?.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: May 3, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Noritaka Kitazawa, Toshihiko Kaneko, Nobuaki Sato, Koki Kawano, Koichi Ito, Mamoru Takaishi, Takeo Sasaki, Yu Yoshida, Toshiyuki Uemura, Takashi Doko, Daisuke Shinmyo, Daiju Hasegawa, Takehiko Miyagawa, Hiroaki Hagiwara
  • Publication number: 20110097955
    Abstract: An object of the present invention is to provide a woven fabric for an airbag which is of low cost, is excellent in accommodability, and has air permeability satisfying the human body initial constraining performance. The present invention provides a woven fabric for an airbag comprising a synthetic fiber woven fabric having a cover factor represented by the equation 1 of 2000 to 2500 in which at least one side thereof is coated with a synthetic resin, wherein air permeability of the woven fabric under a pressure difference of 100 kPa is 0.01 to 1.00 L/cm2/min, and a resin film is present at an upper part of a single yarn at a thickness of 2 ?m or less on a central cross section of a weaving yarn part, while a resin film is present at an upper part of a single yarn at a thickness of 2 to 30 ?m on a cross section at a border between weaving yarn parts.
    Type: Application
    Filed: December 29, 2010
    Publication date: April 28, 2011
    Applicant: Toyo Boseki Kabushiki Kaisha
    Inventors: Kenichiro Kano, Takashi Tsuruta, Mamoru Kitamura, Hideo Isoda, Hiroaki Hagiwara, Gaku Maruyama, Takahiro Hattori
  • Publication number: 20110097956
    Abstract: An object of the present invention is to provide a fabric for an airbag which is of low cost, is excellent in accommodability, and has air permeability satisfying the human body initial constraining performance. The present invention provides a fabric for an airbag comprising a synthetic fiber woven fabric in which at least one side thereof is coated with a synthetic resin, characterized in that a range of 0.1 to 10 g/m2 of a synthetic resin is adhered to the synthetic fiber woven fabric having a cover factor represented by the equation 1 of less than 2000 and FR represented by the equation 2 of 55% or more, and air permeability of the fabric under a pressure difference of 100 kPa after adhesion is 0.01 to 1.00 L/cm2/min.
    Type: Application
    Filed: December 29, 2010
    Publication date: April 28, 2011
    Applicant: Toyo Boseki Kabushiki Kaisha
    Inventors: Kenichiro Kano, Takashi Tsuruta, Hideo Isoda, Hiroaki Hagiwara, Gaku Maruyama, Takahiro Hattori
  • Publication number: 20110086860
    Abstract: A compound represented by Formula (I) is provided: wherein Ar1 represents an imidazolyl group which may be substituted with 1 to 3 substituents; Ar2 represents a phenyl group which may be substituted with 1 to 3 substituents; X1 represents (1) —C?C— or (2) a double bond etc., which may be substituted; R1 and R2 represent, for example, a C1-6 alkyl group which may be substituted, or a pharmacologically acceptable salt thereof and to the use thereof as pharmaceutical agents.
    Type: Application
    Filed: December 21, 2010
    Publication date: April 14, 2011
    Inventors: Teiji KIMURA, Koki Kawano, Eriko Doi, Noritaka Kitazawa, Kogyoku Shin, Takehiko Miyagawa, Toshihiko Kaneko, Koichi Ito, Mamoru Takaishi, Takeo Sasaki, Hiroaki Hagiwara
  • Publication number: 20110065696
    Abstract: A compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group or the like which may be substituted with a C1-6 alkyl group, Ar2 represents a phenyl group or the like which may be substituted with a C1-6 alkoxy group, X1 represents a double bond or the like and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, is effective as a therapeutic or prophylactic agent for a disease caused by A?.
    Type: Application
    Filed: November 19, 2010
    Publication date: March 17, 2011
    Inventors: Teiji KIMURA, Noritaka Kitazawa, Toshihiko Kaneko, Nobuaki Sato, Koki Kawano, Koichi Ito, Mamoru Takaishi, Takeo Sasaki, Yu Yoshida, Toshiyuki Uemura, Takashi Doko, Daisuke Shinmyo, Daiju Hasegawa, Takehiko Miyagawa, Hiroaki Hagiwara
  • Patent number: 7897632
    Abstract: The present invention provides a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that may be substituted with a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that may be substituted with a C1-6 alkyl group, or the like, which is effective as a therapeutic or prophylactic agent for a disease caused by A?.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: March 1, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Noritaka Kitazawa, Toshihiko Kaneko, Nobuaki Sato, Koki Kawano, Koichi Ito, Eriko Doi, Mamoru Takaishi, Takeo Sasaki, Takehiko Miyagawa, Hiroaki Hagiwara, Takashi Doko
  • Patent number: 7880009
    Abstract: The present invention relates to a compound represented by Formula (I): (wherein Ar1 represents an imidazolyl group which may be substituted with 1 to 3 substituents; Ar2 represents a pyridinyl group, a pyrimidinyl group, or a phenyl group which may be substituted with 1 to 3 substituents; X1 represents (1) —C?C— or (2) a double bond etc. which may be substituted; R1 and R2 represent, for example, a C1-6 alkyl group or C3-8 cycloalkyl group which may be substituted) or a pharmacologically acceptable salt thereof and to the use thereof as pharmaceutical agents.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: February 1, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Teiji Kimura, Koki Kawano, Eriko Doi, Noritaka Kitazawa, Kogyoku Shin, Takehiko Miyagawa, Toshihiko Kaneko, Koichi Ito, Mamoru Takaishi, Takeo Sasaki, Hiroaki Hagiwara