Abstract: A pneumatic tire includes: bead cores formed by winding bead wires in a ring shape and having a polygonal cross-section shape in a meridian cross-section; a carcass extended between bead portions on both sides in a width direction, the carcass being folded back to an outer side in the width direction of the bead portion, the carcass being formed by coating a carcass cord with a coating rubber; an inner organic fiber reinforced layer wound around the bead core and formed by coating an organic fiber cord with a coating rubber; and a rubber reinforcing layer between the inner organic fiber reinforced layer and the carcass to cover at least an apex on an innermost side of the bead core in the width direction. A shortest distance between the bead wire and the carcass cord is 3 mm or more.

Abstract: In a pneumatic tire, a bead core has end portions in a tirewidth direction formed as vertical lines along a tireradial direction. A length of the vertical lines is from 20% to 30% of a core height. In two adjacent bead core layers of first, second and third layers, the radial outer layer tireincludes two or more bead cores more than the radially inner layertire, and a misalignment amount between the bead wires each at an end portion on one side in the tirewidth direction is one-half of a bead wire thickness. A side on which the misalignment amount between the first and second layer bead wires is one-half of the thickness of the bead wire is opposite in the tirewidth direction to a side on which the misalignment amount between the second and third layer bead wires is one-half of the thickness of the bead wire.

Abstract: A connector assembly includes a first connector and a second connector, in which the first connector includes: a first signal terminal; a first fixed part which fixes a first part of the first signal terminal; a first terminal which fixes the first signal terminal with the first fixed part held therebetween; a second fixed part which fixes a second part of the first signal terminal; and a second terminal inside which the first signal terminal is fixed with the second fixed part held therebetween, the second connector includes: a second signal terminal; a third fixed part which fixes the second signal terminal; and a third terminal which fixes the second signal terminal with the third fixed part held therebetween, and since a diameter of the bending part is smaller than a diameter of the second part, the second fixed part is caught on the second part and is retained.

Abstract: A pneumatic tire includes lug grooves having alternating first and second groove portions. The first groove portion intersects an equator, extends in a width direction, and communicates with an adjacent second groove portion. The second groove portion inclines from the first groove portion at a smaller angle relative to a circumferential direction smaller than that of the first groove portion and extends to a tread edge on one side. The first groove portion is on a stepping side with respect to an end on the tread edge side. The second groove portions curve or bend and have an average angle in an inner region smaller than that of the second groove portions in an outer region. A maximum length in the width direction of center blocks defined by narrow grooves connecting adjacent second groove portions and the lug grooves is 25%-35% of a development width.

Abstract: A semiconductor device with favorable reliability is provided. The semiconductor device includes a first oxide, a second oxide, a first conductor, a second conductor, a third conductor, a first insulator, and a second insulator. The first conductor is provided in contact with a top surface of the first oxide. The second conductor is provided in contact with the top surface of the first oxide. The first insulator is provided over the first conductor and the second conductor. The second oxide is provided in contact with the top surface of the first oxide. The second insulator is provided over the second oxide. The third conductor is provided over the second insulator. The first insulator has a function of inhibiting diffusion of oxygen. The first oxide includes indium, an element M (M is gallium, yttrium, or tin), and zinc. The first oxide includes a first region overlapping with the third conductor.

Abstract: Therapeutic agents and treatment methods for urologic cancers, particularly urologic cancers with reduced lysine (K)-specific demethylase 6A (KDM6A) function, the agents and methods being characterized by suppressing both IL-6 activity and CCR2/CCL2 activity, are provided.

Abstract: A semiconductor device with small variations in transistor characteristics is provided. The semiconductor device includes an oxide; a first conductor and a second conductor provided apart from each other over the oxide; an insulator in a region between the first conductor and the second conductor over the oxide; and a conductor over the insulator. A side surface of the oxide, a top surface of the first conductor, a side surface of the first conductor, a top surface of the second conductor, and a side surface of the second conductor include regions in contact with a nitride containing silicon.

Abstract: In a pneumatic tire mountable on a 5°-tapered rim, a bottom of a bead core is inclined from 0°-5° in a direction in which the bottom diverges toward an outer side in a radial direction as the bottom extends from an inner side in the width direction toward an outer side in the width direction. Each bead portion includes a base, a toe, and a heel. The base is inclined from 8°-12° in a direction in which the bead base portion diverges toward the outer side in the radial direction as the base extends from the inner side toward the outer side in the width direction. The heel has a radius of curvature from 25-30 mm. A rim cushion rubber has a modulus at 100% elongation within a range from 5.0-8.0 MPa. The toe has a displacement between before and after mounting on the rim from 9.0-13.5 mm.

Abstract: A pneumatic tire includes alternating first and second groove portions. The first groove portion intersects an equator and extends in a width direction. The second groove portion inclines from the first groove portion to a tread edge at a smaller angle relative to a circumferential direction than an angle of the first groove portion relative to the circumferential direction. The first groove portion communicates with the second groove portion of the lug groove adjacent in the circumferential direction. The first groove portion is on a stepping side of each lug groove. The second groove portions are curved or bent and an average angle of the second groove portions in an inner region is smaller than in an outer region. Shallow grooves having a bent point are formed on blocks. The blocks are defined by circumferential narrow grooves connecting the second groove portions adjacent in the circumferential direction and the lug grooves.

Abstract: In a pneumatic tire mountable on a 5°-tapered rim, a bottom of a bead core is inclined from 0°-5° in a direction in which the bottom diverges toward an outer side in a radial direction as the bottom extends from an inner side in the width direction toward an outer side in the width direction. Each bead portion includes a base, a toe, and a heel. The base is inclined from 8°-12° in a direction in which the bead base portion diverges toward the outer side in the radial direction as the base extends from the inner side toward the outer side in the width direction. The heel has a radius of curvature from 25-30 mm. A rim cushion rubber has a modulus at 100% elongation within a range from 5.0-8.0 MPa. The toe has a displacement between before and after mounting on the rim from 9.0-13.5 mm.

Abstract: A semiconductor device having favorable electrical characteristics is provided. The semiconductor device includes an oxide; a first conductor and a second conductor over the oxide; a third conductor over the oxide; a first insulator provided between the oxide and the third conductor and covering a side surface of the third conductor; a second insulator over the third conductor and the first insulator; a third insulator positioned over the first conductor and at a side surface of the second insulator; a fourth insulator positioned over the second conductor and at a side surface of the second insulator; a fourth conductor being in contact with a top surface and a side surface of the third insulator and electrically connected to the first conductor; and a fifth conductor being in contact with a top surface and a side surface of the fourth insulator and electrically connected to the second conductor.

Abstract: A semiconductor device with favorable reliability is provided. The semiconductor device includes a first oxide, a second oxide, a first conductor, a second conductor, a third conductor, a first insulator, and a second insulator. The first conductor is provided in contact with a top surface of the first oxide. The second conductor is provided in contact with the top surface of the first oxide. The first insulator is provided over the first conductor and the second conductor. The second oxide is provided in contact with the top surface of the first oxide. The second insulator is provided over the second oxide. The third conductor is provided over the second insulator. The first insulator has a function of inhibiting diffusion of oxygen. The first oxide includes indium, an element M (M is gallium, yttrium, or tin), and zinc. The first oxide includes a first region overlapping with the third conductor.

Abstract: A pneumatic tire includes alternating first and second groove portions. The first groove portion intersects an equator and extends in a width direction. The second groove portion inclines from the first groove portion to a tread edge at a smaller angle relative to a circumferential direction than an angle of the first groove portion relative to the circumferential direction. The first groove portion communicates with the second groove portion of the lug groove adjacent in the circumferential direction. The first groove portion is on a stepping side of each lug groove. The second groove portions are curved or bent and an average angle of the second groove portions in an inner region is smaller than in an outer region. Shallow grooves having a bent point are formed on blocks. The blocks are defined by circumferential narrow grooves connecting the second groove portions adjacent in the circumferential direction and the lug grooves.

Abstract: A semiconductor device which can suppress leakage current between a wiring and a connection electrode connected to a floating node is provided. The semiconductor device includes a first insulator, a first conductor over the first insulator, a second conductor over the first insulator, and a second insulator over the first insulator, the first conductor, and the second conductor. The first conductor and the second conductor contain a metal A (one kind or a plurality of kinds of aluminum, copper, tungsten, chromium, silver, gold, platinum, tantalum, nickel, molybdenum, magnesium, beryllium, indium, and ruthenium). The metal A is detected in an interface between the first insulator and the second insulator by an energy dispersive X-ray spectroscopy (EDX). The second insulator includes a groove for exposing the first insulator between the first conductor and the second conductor.

Abstract: A pneumatic tire includes lug grooves having alternating first and second groove portions. The first groove portion intersects an equator, extends in a width direction, and communicates with an adjacent second groove portion. The second groove portion inclines from the first groove portion at a smaller angle relative to a circumferential direction smaller than that of the first groove portion and extends to a tread edge on one side. The first groove portion is on a stepping side with respect to an end on the tread edge side. The second groove portions curve or bend and have an average angle in an inner region smaller than that of the second groove portions in an outer region. A maximum length in the width direction of center blocks defined by narrow grooves connecting adjacent second groove portions and the lug grooves is 25%-35% of a development width.

Abstract: A transistor includes a first insulator over a substrate; a first oxide thereover; a second oxide in contact with at least part of the top surface of the first oxide; a first conductor and a second conductor each in contact with at least part of the top surface of the second oxide; a third oxide that is over the first conductor and the second conductor and is in contact with at least part of the top surface of the second oxide; a second insulator thereover; a third conductor which is over the second insulator and at least part of which overlaps with a region between the first conductor and the second conductor; and a third insulator which is over the third conductor and at least part of which is in contact with the top surface of the first insulator. The thickness of a region of the first insulator that is in contact with the third insulator is less than the thickness of a region of the first insulator that is in contact with the first oxide.

Abstract: A semiconductor device which can suppress leakage current between a wiring and a connection electrode connected to a floating node is provided. The semiconductor device includes a first insulator, a first conductor over the first insulator, a second conductor over the first insulator, and a second insulator over the first insulator, the first conductor, and the second conductor. The first conductor and the second conductor contain a metal A (one kind or a plurality of kinds of aluminum, copper, tungsten, chromium, silver, gold, platinum, tantalum, nickel, molybdenum, magnesium, beryllium, indium, and ruthenium). The metal A is detected in an interface between the first insulator and the second insulator by an energy dispersive X-ray spectroscopy (EDX). The second insulator includes a groove for exposing the first insulator between the first conductor and the second conductor.

Abstract: A fatigue level calculating device includes an environment information acquiring unit that acquires environment information pertaining to an environment in the surroundings of equipment, and a fatigue level calculating unit that calculates a relationship between an operation condition of the equipment and a fatigue level of the equipment based on the environment information.

Abstract: A semiconductor device having favorable electrical characteristics is provided. The semiconductor device includes an oxide; a first conductor and a second conductor over the oxide; a third conductor over the oxide; a first insulator provided between the oxide and the third conductor and covering a side surface of the third conductor; a second insulator over the third conductor and the first insulator; a third insulator positioned over the first conductor and at a side surface of the second insulator; a fourth insulator positioned over the second conductor and at a side surface of the second insulator; a fourth conductor being in contact with a top surface and a side surface of the third insulator and electrically connected to the first conductor; and a fifth conductor being in contact with a top surface and a side surface of the fourth insulator and electrically connected to the second conductor.

Abstract: A semiconductor device which can suppress leakage current between a wiring and a connection electrode connected to a floating node is provided. The semiconductor device includes a first insulator, a first conductor over the first insulator, a second conductor over the first insulator, and a second insulator over the first insulator, the first conductor, and the second conductor. The first conductor and the second conductor contain a metal A (one kind or a plurality of kinds of aluminum, copper, tungsten, chromium, silver, gold, platinum, tantalum, nickel, molybdenum, magnesium, beryllium, indium, and ruthenium). The metal A is detected in an interface between the first insulator and the second insulator by an energy dispersive X-ray spectroscopy (EDX). The second insulator includes a groove for exposing the first insulator between the first conductor and the second conductor.