Abstract: The sound absorbing material according to the present invention is formed by laminating a porous sound absorber and two or more sheets of a nonwoven fabric one on another. The nonwoven fabric has a plurality of drawn filaments arranged and oriented in one direction. The mode value of the diameter distribution of the plurality of filaments is in the range of 1 to 4 ?m. The grammage of the nonwoven fabric is in the range of 5 to 40 g/m2. The sound absorbing material according to the present invention provides high sound absorption performance in a predetermined low frequency band of 6000 Hz or less, and still remains light in weight and flexible enough and easy enough to handle to be substantially comparable to the porous sound absorber.

Abstract: The present invention relates to a platelet aggregating agent containing amorphous polyphosphate as an active ingredient, wherein the polyphosphate is a Ca salt of polyphosphate. The platelet aggregating agent acts on damaged gastrointestinal mucosa in inflammatory bowel disease and exerts a platelet aggregating action, thereby allowing remission/improvement of the inflammatory bowel disease.

Abstract: This is a resin composition for a film containing an ionomer which comprises, in a copolymer (P) containing a structural unit (A) derived from ethylene and/or an ?-olefin having 3 to 20 carbon atoms, and a structural unit (B) derived from a monomer having a carboxyl group(s) and/or a dicarboxylic anhydride group(s) as essential constitutional units, at least a part of the carboxyl groups and/or the dicarboxylic anhydride groups in the copolymer (P) being converted into a metal-containing carboxylic acid salt(s) containing at least one kind of a metal ion(s) selected from Group 1, Group 2 or Group 12 of the periodic table, and having a phase angle ? at an absolute value G*=0.1 MPa of a complex modulus of elasticity measured by a rotary rheometer of 50 degrees to 75 degrees, and a molded body molded by using the same.

Abstract: An object of the present invention is to provide an echinomycin derivative that has anti-cancer activity equal to or greater than that of echinomycin, and a production method therefor based on a chemical procedure. Provided are an echinomycin derivative represented by formula (I), and a production method therefor based on a chemical procedure.

Abstract: Provided is a method for using a STAT3 inhibitor having a high antitumor effect and little side effects. The antitumor agent comprises a combination of a quinoline carboxamide derivative of formula (I) below or a pharmacologically acceptable salt thereof with one or more cancer molecular target drugs selected from the group consisting of an ALK inhibitor, an EGFR inhibitor, a multi kinase inhibitor, a HER2/EGFR inhibitor, an mTOR inhibitor, a BRAF inhibitor, a MEK inhibitor and a BCR-ABL inhibitor, wherein R1, R2, R3, R4, R5 and R6 are the same or different, and each represent a hydrogen atom, a substituted or unsubstituted aryl group, a substituted or unsubstituted aromatic heterocyclic group, COOR7 (wherein R7 represents a substituted or unsubstituted alkyl group), or OR8 (wherein R8 represents a substituted or unsubstituted alkyl group).

Abstract: The phosphine transition metal complex of the present invention is represented by formula (1). Preferably, R1 and R6 are identical groups, R2 and R7 are identical groups, R3 and R8 are identical groups, R4 and R9 are identical groups, R5 and R10 are identical groups, and n and y are identical numbers. The phosphine transition metal complex is suitably obtained by reacting a phosphine derivative represented by formula (2) and a phosphine derivative represented by formula (3) with a salt of a transition metal of gold, copper or silver. See the description for the meanings of the symbols in each formula.

Abstract: The phosphine transition metal complex of the present invention is represented by formula (1). Preferably, R1 and R6 are identical groups, R2 and R7 are identical groups, R3 and R8 are identical groups, R4 and R9 are identical groups, R5 and R10 are identical groups, and n and y are identical numbers. The phosphine transition metal complex is suitably obtained by reacting a phosphine derivative represented by formula (2) and a phosphine derivative represented by formula (3) with a salt of a transition metal of gold, copper or silver. See the description for the meanings of the symbols in each formula.

Abstract: A nonwoven fabric according to the present invention is formed so that constituent fibers of the nonwoven fabric have an average fiber diameter of less than 1 ?m and the number of fibers having fiber diameters ranging from 2 times up to 10 times the average fiber diameter of the constituent fibers is in a range of 2 to 20% of a total number of the constituent fibers. When the nonwoven fabric according to the present invention is used as a filter layer constituting an air filter, for example, it is possible to achieve high collection efficiency while reducing clogging (packing) between fibers to solve problems that may occur in using the conventional nanofiber nonwoven fabric (such as an increase in pressure loss and a decrease in service life).

Abstract: An object of the present invention is to provide an echinomycin derivative that has anti-cancer activity equal to or greater than that of echinomycin, and a production method therefor based on a chemical procedure. Provided are an echinomycin derivative represented by formula (I), and a production method therefor based on a chemical procedure.

Abstract: The sound absorbing material according to the present invention is formed by laminating a porous sound absorber and two or more sheets of a nonwoven fabric one on another. The nonwoven fabric has a plurality of drawn filaments arranged and oriented in one direction. The mode value of the diameter distribution of the plurality of filaments is in the range of 1 to 4 ?m. The grammage of the nonwoven fabric is in the range of 5 to 40 g/m2. The sound absorbing material according to the present invention provides high sound absorption performance in a predetermined low frequency band of 6000 Hz or less, and still remains light in weight and flexible enough and easy enough to handle to be substantially comparable to the porous sound absorber.

Abstract: [Problem] To provide a highly safe and efficacious antitumor agent that is derived from probiotics. [Solution] The present invention relates to an antitumor agent comprising a compound represented by formula (1) or a complex thereof as an active ingredient. In formula (1): R1 represents a hydrogen atom or a hydroxymethyl group; R2 represents a hydrogen atom, a methyl group or a hydroxymethyl group; and R3, R4 and R5 each independently represent a methyl group, an N5-(trans-5-hydroxy-3-methylpent-2-enoyl) group, an N5-(cis-5-hydroxy-3-methylpent-2-enoyl) group or an N5-(trans-4-carboxy-3-methylpent-2-enoyl) group. According to the present invention, a highly safe and efficacious antitumor agent can be provided.

Abstract: A nonwoven sound absorbing material according to the present invention includes a nonwoven laminate formed of a stack of a plurality of sheets of a filament nonwoven fabric having a plurality of drawn filaments arranged and oriented in one direction, and the mode value of the diameter distribution of the plurality of drawn filaments is 1 to 4 ?m. The nonwoven sound absorbing material according to the present invention has improved sound absorption performance in a relatively low frequency band as compared to a conventional one.

Abstract: A nonwoven fabric for sound absorbing application according to the present invention includes a plurality of drawn filaments arranged and oriented in one direction, and the mode value of the diameter distribution of the plurality of drawn filaments is 1 to 4 ?m. When laminated on a porous sound absorbing material, the nonwoven fabric for sound absorbing application according to the present invention constitutes a sound absorbing material with the porous sound absorbing material, and the resultant laminated sound absorbing material has improved sound absorption performance in the frequency band of 1000 to 10000 Hz as compared to the porous sound absorbing material alone.

Abstract: A method for manufacturing ultrafine fibers having an average diameter of less than 1 ?m is implemented by an apparatus including a feeder and a drawing chamber in communication with the feeder via an orifice having a pressure difference. The method includes introducing a multifilament to the drawing chamber under the condition that the ratio of the cross-section of the multifilament to the cross-section of the orifice rectifier is 50% or less, and irradiating the discharged multifilament such that the center of the multifilament melted thereby is located 1 to 15 mm apart vertically below the orifice outlet to melt the leading portion of the multifilament and cause the multifilament to swing at a maximum angle of 5 to 80 degrees to the central orifice axis within a conical space, such that the melted leading portion of the multifilament is drawn by an air stream generated by the pressure difference.

Abstract: [Problem] To provide a highly safe and efficacious antitumor agent that is derived from probiotics. [Solution] The present invention relates to an antitumor agent comprising a compound represented by formula (1) or a complex thereof as an active ingredient. In formula (1): R1 represents a hydrogen atom or a hydroxymethyl group; R2 represents a hydrogen atom, a methyl group or a hydroxymethyl group; and R3, R4 and R5 each independently represent a methyl group, an N5-(trans-5-hydroxy-3-methylpent-2-enoyl) group, an N5-(cis-5-hydroxy-3-methylpent-2-enoyl) group or an N5-(trans-4-carboxy-3-methylpent-2-enoyl) group. According to the present invention, a highly safe and efficacious antitumor agent can be provided.

Abstract: A nonwoven fabric according to the present invention is formed so that constituent fibers of the nonwoven fabric have an average fiber diameter of less than 1 ?m and the number of fibers having fiber diameters ranging from 2 times up to 10 times the average fiber diameter of the constituent fibers is in a range of 2 to 20% of a total number of the constituent fibers. When the nonwoven fabric according to the present invention is used as a filter layer constituting an air filter, for example, it is possible to achieve high collection efficiency while reducing clogging (packing) between fibers to solve problems that may occur in using the conventional nanofiber nonwoven fabric (such as an increase in pressure loss and a decrease in service life).

Abstract: A method for manufacturing ultrafine fibers having an average diameter of less than 1 urn is implemented by an apparatus including a feeder and a drawing chamber in communication with the feeder via an orifice having a pressure difference. The method includes introducing a multifilament to the drawing chamber under the condition that the ratio of the cross-section of the multifilament to the cross-section of the orifice rectifier is 50% or less, and irradiating the discharged multifilament such that the center of the multifilament melted thereby is located I to 15 mm apart vertically below the orifice outlet to melt the leading portion of the multifilament and cause the multifilament to swing at a maximum angle of 5 to 80 degrees to the central orifice axis within a conical space, such that the melted leading portion of the multifilament is drawn by an air stream generated by the pressure difference.

Abstract: A lithium-ion secondary battery separator resolves defects of a non-woven fabric separator which is not suitable for use in such a battery. The separator is thin and does not short-circuit and has excellent electrolyte retainability and rate characteristics. The separator includes a composite of a non-woven fabric having a basis weight of 2 to 20 g/m2 formed from fibers of a thermoplastic material having an average fiber diameter of 5 to 40 ?m and ultra-microfibers having an average fiber diameter of 1 ?m or less in an amount of ? to 3 times the mass of the non-woven fabric. The composite has a thickness of 10 to 40 ?m after heat-pressing treatment under conditions that the non-woven fabric has a glossiness (JIS Z 8741) measured at 60° in the range of 3 to 30 and a thickness of 10 to 40.

Abstract: The present invention provides a rechargeable organic electrolyte battery that can be safely used continuously even if abnormality in battery voltage control occurs during use. The rechargeable organic electrolyte battery comprises cathodes, anodes, insulating sheets comprising a resin having no oxygen-containing group electrically insulating the cathodes and anodes from each other, and an organic electrolyte containing reactive ionic species, all contained in a sealed structure, the terminals of the cathodes and anodes being externally pulled out, wherein the insulating sheets are each an assembly of nanoscale filaments and microscale filaments, or a laminate of an assembly of nanoscale filaments and an assembly of microscale filaments.

Abstract: The objective of the present invention is to provide a lithium ion secondary battery, the charged state of which can be detected from the battery voltage with high accuracy, and which is able to achieve a high capacity in a high-potential range. This objective can be achieved by a cathode active material for lithium ion secondary batteries, which is composed of a lithium transition metal oxide containing Li and metal elements including at least Ni and Mn, and which is characterized in that: the atomic ratio of Li to the metal elements satisfies 1.15<Lil(metal elements)<1.5; the atomic ratio of Ni to Mn satisfies 0.334<Ni/Mn?1; and the atomic ratio of Ni and Mn to the metal elements satisfies 0.975?(Ni+Mn)/(metal elements)?1.