Patents by Inventor Hiroaki Tobimatsu
Hiroaki Tobimatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11325120Abstract: This specimen treatment chip includes: a first fluid module having a first flow channel for performing a first treatment step on an object component in a specimen; a second fluid module having a second flow channel for performing a second treatment step on the object component subjected to the first treatment step; a substrate; and a connection flow channel for connecting the first fluid module and the second fluid module disposed on the substrate.Type: GrantFiled: April 6, 2018Date of Patent: May 10, 2022Assignee: SYSMEX CORPORATIONInventors: Ayato Tagawa, Tsuyoshi Nakano, Yasuko Kawamoto, Koya Yamawaki, Hiroaki Tobimatsu
-
Patent number: 11169057Abstract: A particle dispersion method for dispersing particles (500) fixed on the inner surface of a container (12) into a liquid. The particle dispersion method includes a discharge step of discharging a liquid into the container (12). The container (12) has a cylindrical main body part (310), and an inclined part (311) having an inner diameter that decreases from the main body part (310) side to the bottom part side and having a constant angle relative to the central axis of the container. In the discharge step, the liquid is discharged from above the inclined part (311) toward the inclined part (311) on the side opposite the particles (500) fixed to the inner surface of the container (12) across the central axis (300) of the container (12).Type: GrantFiled: November 29, 2017Date of Patent: November 9, 2021Assignee: Sysmex CorporationInventors: Hiroaki Tobimatsu, Toshimi Sato
-
Patent number: 11060081Abstract: Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma specimen; a reagent container holder configured to hold a first reagent container for containing a first reagent including magnetic particles on which a nucleic acid in the plasma specimen is adsorbed; a reaction unit in which a plurality of reaction containers are disposed, the reaction unit being configured to accelerate, in each reaction container, reaction of the plasma specimen and the first reagent; a washing unit in which a washing container is disposed, the washing unit including a magnetic force applying portion configured to apply magnetic force to the washing container; a dispensing unit; and a controller programmed to control the dispensing unit to: dispense the plasma specimen contained in the specimen container and the first reagent into the plurality of reaction containers in the reaction unit; dispense a mix liquid of the plasma specimen and theType: GrantFiled: February 27, 2017Date of Patent: July 13, 2021Assignee: SYSMEX CORPORATIONInventors: Yasuhiro Sakai, Hiroaki Tobimatsu, Takeo Saitou, Tomoko Ohyama, Takanori Maekawa
-
Patent number: 10948507Abstract: A specimen transport apparatus according to an embodiment includes: a holder including first and second trenches and configured to hold a specimen; a first transporter including a first protrusion to engage with the first trench and configured to transport the holder by transferring the first protrusion engaged with the first trench in an extension direction of the second trench; a second transporter including a second protrusion to engage with the second trench and configured to transport the holder by transferring the second protrusion engaged with the second trench in an extension direction of the first trench. The first trench is formed in at least one of an upper surface and a lower surface of the holder. The second trench is formed in at least one of the upper surface and the lower surface of the holder, and is formed to extend to a lateral surface of the holder.Type: GrantFiled: November 28, 2017Date of Patent: March 16, 2021Assignee: SYSMEX CORPORATIONInventors: Yuto Sasaki, Kazuki Asao, Kazuyuki Iguchi, Keiichiro Shohmi, Shoichiro Asada, Hiroaki Tobimatsu, Ryutaro Shinya
-
Patent number: 10648996Abstract: A specimen measurement apparatus may include: an aspirator via which a specimen is aspirated. A flow path may be connected to the aspirator. A first pump may be connected to the flow path. A second pump may be connected to the flow path. A controller may select and cause either the first pump or the second pump to aspirate the specimen via the aspirator.Type: GrantFiled: December 27, 2017Date of Patent: May 12, 2020Assignee: SYSMEX CORPORATIONInventors: Toru Mizuhashi, Hiroaki Tobimatsu, Tomoya Hayashi
-
Publication number: 20180221881Abstract: The present specimen treatment chip includes: a first flow channel for forming a droplet containing a mixed liquid of a nucleic acid, a reagent for an amplification reaction of the nucleic acid, and a carrier to which a primer for binding to the nucleic acid is added, in a dispersion medium; a second flow channel for amplifying the nucleic acid in the droplet; and a third flow channel for mixing the droplet containing the carrier with the primer having bound to an amplification product of the nucleic acid, and a reagent for breaking down the droplet, to break down the droplet.Type: ApplicationFiled: April 6, 2018Publication date: August 9, 2018Inventors: Ayato TAGAWA, Tsuyoshi NAKANO, Yasuko KAWAMOTO, Koya YAMAWAKI, Hiroaki TOBIMATSU
-
Publication number: 20180221878Abstract: This specimen treatment chip includes: a first fluid module having a first flow channel for performing a first treatment step on an object component in a specimen; a second fluid module having a second flow channel for performing a second treatment step on the object component subjected to the first treatment step; a substrate; and a connection flow channel for connecting the first fluid module and the second fluid module disposed on the substrate.Type: ApplicationFiled: April 6, 2018Publication date: August 9, 2018Inventors: Ayato TAGAWA, Tsuyoshi NAKANO, Yasuko KAWAMOTO, Koya YAMAWAKI, Hiroaki TOBIMATSU
-
Publication number: 20180180638Abstract: A specimen measurement apparatus may include: an aspirator via which a specimen is aspirated. A flow path may be connected to the aspirator. A first pump may be connected to the flow path. A second pump may be connected to the flow path. A controller may select and cause either the first pump or the second pump to aspirate the specimen via the aspirator.Type: ApplicationFiled: December 27, 2017Publication date: June 28, 2018Applicant: SYSMEX CORPORATIONInventors: Toru MIZUHASHI, Hiroaki TOBIMATSU, Tomoya HAYASHI
-
Publication number: 20180149667Abstract: A specimen transport apparatus according to an embodiment includes: a holder including first and second trenches and configured to hold a specimen; a first transporter including a first protrusion to engage with the first trench and configured to transport the holder by transferring the first protrusion engaged with the first trench in an extension direction of the second trench; a second transporter including a second protrusion to engage with the second trench and configured to transport the holder by transferring the second protrusion engaged with the second trench in an extension direction of the first trench. The first trench is formed in at least one of an upper surface and a lower surface of the holder. The second trench is formed in at least one of the upper surface and the lower surface of the holder, and is formed to extend to a lateral surface of the holder.Type: ApplicationFiled: November 28, 2017Publication date: May 31, 2018Applicant: SYSMEX CORPORATIONInventors: Yuto SASAKI, Kazuki ASAO, Kazuyuki IGUCHI, Keiichiro SHOHMI, Shoichiro ASADA, Hiroaki TOBIMATSU, Ryutaro SHINYA
-
Publication number: 20180149564Abstract: A particle dispersion method for dispersing particles (500) fixed on the inner surface of a container (12) into a liquid. The particle dispersion method includes a discharge step of discharging a liquid into the container (12). The container (12) has a cylindrical main body part (310), and an inclined part (311) having an inner diameter that decreases from the main body part (310) side to the bottom part side and having a constant angle relative to the central axis of the container. In the discharge step, the liquid is discharged from above the inclined part (311) toward the inclined part (311) on the side opposite the particles (500) fixed to the inner surface of the container (12) across the central axis (300) of the container (12).Type: ApplicationFiled: November 29, 2017Publication date: May 31, 2018Inventors: Hiroaki TOBIMATSU, Toshimi SATO
-
Publication number: 20170247682Abstract: Disclosed is a specimen pretreatment apparatus comprising: a specimen container holder configured to hold a specimen container for containing a plasma specimen; a reagent container holder configured to hold a first reagent container for containing a first reagent including magnetic particles on which a nucleic acid in the plasma specimen is adsorbed; a reaction unit in which a plurality of reaction containers are disposed, the reaction unit being configured to accelerate, in each reaction container, reaction of the plasma specimen and the first reagent; a washing unit in which a washing container is disposed, the washing unit including a magnetic force applying portion configured to apply magnetic force to the washing container; a dispensing unit; and a controller programmed to control the dispensing unit to: dispense the plasma specimen contained in the specimen container and the first reagent into the plurality of reaction containers in the reaction unit; dispense a mix liquid of the plasma specimen and theType: ApplicationFiled: February 27, 2017Publication date: August 31, 2017Inventors: Yasuhiro SAKAI, Hiroaki TOBIMATSU, Takeo SAITOU, Tomoko OHYAMA, Takanori MAEKAWA
-
Patent number: 9429509Abstract: Particle analyzers are described that include a cell for receiving a particles-containing liquid; a light source for irradiating light onto the particles-containing liquid; a photo-detector for detecting optical information from particles in the particles-containing liquid and converting the optical information into an electric signal; a temperature sensor for detecting a temperature of the particles-containing liquid; and a signal processing section for calculating an analysis result of the particles on the basis of an output of the photo-detector and an output of the temperature sensor. Particle analysis methods are also described.Type: GrantFiled: January 27, 2003Date of Patent: August 30, 2016Assignee: SYSMEX CORPORATIONInventors: Takaaki Nagai, Kazuhiro Yamada, Hiroaki Tobimatsu
-
Publication number: 20080102443Abstract: The present invention is to present a column cartridge that enables the obtainment of a plurality of analysis objects from a single sample easily. The column cartridge comprises: a first liquid sample receiving part having an opening for receiving a liquid sample; a carrier for isolating a target substance from the liquid sample; a carrier holding part for holding the carrier; and a flow path part comprising a flow path through which the liquid sample is able to pass after passing through the carrier held by the carrier holding part, and being configured to be fitted into an opening of a second liquid sample receiving part of another column cartridge.Type: ApplicationFiled: October 31, 2007Publication date: May 1, 2008Applicant: SYSMEX CORPORATIONInventors: Masakazu FUKUDA, Hiroaki TOBIMATSU
-
Patent number: 7355194Abstract: An optical device is described that include: a photoemitter for emitting light, a mounting unit for installing a transparent container accommodating a sample to be subjected to detection, a photoreceptor for receiving the light emitted by a photoemitter and transmitted through the transparent container installed in the mounting unit, a first member disposed between the transparent container and the photoreceptor and having a first pinhole through which passes the light transmitted through the transparent container, and a second member disposed between the first member and the photoreceptor and having a second pinhole through which passes the transmitted light that has passed through the first pinhole.Type: GrantFiled: January 21, 2005Date of Patent: April 8, 2008Assignee: Sysmex CorporationInventor: Hiroaki Tobimatsu
-
Patent number: 7344048Abstract: A dispensing device is described that comprises a base, a chip attaching member which is provided movably with respect to the base and to which a dispensing chip is attached removably, a first elastic member for suppressing a movement of the chip attaching member with respect to the base, a second elastic member serving to suppress the movement of the chip attaching member with respect to the base and having a greater elastic constant than an elastic constant of the first elastic member and a detector for detecting that the chip attaching member is moved with respect to the base. An analyzing apparatus is also described.Type: GrantFiled: January 21, 2005Date of Patent: March 18, 2008Assignee: Sysmex CorporationInventors: Makoto Ueda, Kazuyuki Sakurai, Hiroaki Tobimatsu
-
Publication number: 20050194394Abstract: A dispensing device is described that comprises a base, a chip attaching member which is provided movably with respect to the base and to which a dispensing chip is attached removably, a first elastic member for suppressing a movement of the chip attaching member with respect to the base, a second elastic member serving to suppress the movement of the chip attaching member with respect to the base and having a greater elastic constant than an elastic constant of the first elastic member and a detector for detecting that the chip attaching member is moved with respect to the base. An analyzing apparatus is also described.Type: ApplicationFiled: January 21, 2005Publication date: September 8, 2005Inventors: Makoto Ueda, Kazuyuki Sakurai, Hiroaki Tobimatsu
-
Publication number: 20050156124Abstract: An optical device is described that include: a photoemitter for emitting light, a mounting unit for installing a transparent container accommodating a sample to be subjected to detection, a photoreceptor for receiving the light emitted by a photoemitter and transmitted through the transparent container installed in the mounting unit, a first member disposed between the transparent container and the photoreceptor and having a first pinhole through which passes the light transmitted through the transparent container, and a second member disposed between the first member and the photoreceptor and having a second pinhole through which passes the transmitted light that has passed through the first pinhole.Type: ApplicationFiled: January 21, 2005Publication date: July 21, 2005Inventor: Hiroaki Tobimatsu
-
Publication number: 20050042138Abstract: A sample analyzer allowing miniaturization and sufficiently prompt analysis is obtained. This sample analyzer comprises a dispensing part rendered movable above a sample container set part, a reagent container set part and a detection part for sucking a sample and a reagent from the sample container and the reagent container respectively while discharging the sucked sample and the sucked reagent into the detection container. The detection part is arranged oppositely to the sample container set part and the reagent container set part.Type: ApplicationFiled: August 19, 2004Publication date: February 24, 2005Inventors: Makoto Ueda, Hisaaki Inoue, Kazuyuki Sakurai, Eiji Tanoshima, Yuuji Wakamiya, Hiroaki Tobimatsu, Yuichi Nagame
-
Publication number: 20050042145Abstract: A container for an analyzer capable of preventing a sample or a reagent from contamination is obtained. This container for an analyzer comprises a container body, having an opening, storing a sample therein, a lid member, coupled to the container body, having a closing part closing the opening of the container body, and a closing state holding part holding the closing part in a state closing the opening.Type: ApplicationFiled: August 19, 2004Publication date: February 24, 2005Inventors: Makoto Ueda, Kazuyuki Sakurai, Hiroaki Tobimatsu
-
Patent number: 6694747Abstract: A liquid container comprising a base having openings that communicate from the front surface to the back surface, and first and second sealing plates that seal the openings from both sides of the base to form internal spaces, wherein the sealing plates comprise a first heat exchanging member for heating or cooling the internal space from the front surface of the base and a second heat exchanging member for heating or cooling the internal space from the back surface of the base.Type: GrantFiled: June 4, 2002Date of Patent: February 24, 2004Assignee: Sysmex CorporationInventors: Takaaki Nagai, Hiroaki Tobimatsu