Patents by Inventor Hiroaki Uematsu

Hiroaki Uematsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7119194
    Abstract: A nucleic acid-bondable magnetic carrier of the present invention is a magnetic silica particle comprising a superparamagnetic metal oxide, wherein the magnetic silica particle has a specific surface of about 100 to about 800 m2/g.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: October 10, 2006
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Hiroaki Uematsu, Katsuya Daimon, Satoko Yoshiga
  • Publication number: 20030096987
    Abstract: A nucleic acid-bondable magnetic carrier of the present invention is a magnetic silica particle comprising a superparamagnetic metal oxide, wherein the magnetic silica particle has a specific surface of about 100 to about 800 m2/g.
    Type: Application
    Filed: July 22, 2002
    Publication date: May 22, 2003
    Applicant: Toyo Boseki Kabushiki Kaisha
    Inventors: Hiroaki Uematsu, Katsuya Daimon, Satoko Yoshiga
  • Patent number: 6146882
    Abstract: An incubator comprises an incubating block (12) for incubating a sample at an any desired processing temperature by storing a well rack (14) held the sample such as specimens for instance, under that temperature, a cooling block (13) set to a cooling temperature, a dummy rack (15) which are cooled in the cooling block (13) during an incubating process, as well as first and second pushers (18a, 18b) and first and second carriages (19a, 19b) which together exchange the well rack (14) and the dummy rack (15) with each other.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: November 14, 2000
    Assignees: Toyo Boseki Kabushiki Kaisha, Furuno Electric Co, Ltd.
    Inventors: Hiroaki Uematsu, Takashi Nakajima, Tatsuo Arai, Keiji Okumoto
  • Patent number: 5945525
    Abstract: A nucleic acid-bondable magnetic carrier of the present invention is a magnetic silica particle comprising a superparamagnetic metal oxide, wherein the magnetic silica particle has a specific surface of about 100 to about 800 m.sup.2 /g.
    Type: Grant
    Filed: July 8, 1996
    Date of Patent: August 31, 1999
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Hiroaki Uematsu, Katsuya Daimon, Satoko Yoshiga
  • Patent number: 5538849
    Abstract: An apparatus is presented for an automated assay of a DNA probe, which is performed by hybridizing a nucleic acid in a sample with a DNA probe marked with an enzyme and optically measuring a change that occurs in the substrate by catalysis of the enzyme which is bound with the DNA probe. The DNA probe hybridizes with the nucleic acid in the sample to assay the nucleic acid in the sample. Comprising (A) a sample-reagent unit, (B) a sample-reagent dispense unit, (C) a reaction vessel transport unit, (D) a hybridization unit, (E) a B/F separation unit, and (F) a light measurement unit; also presented is a method for assaying a nucleic acid in a sample by the apparatus of the present invention. According to the measurement apparatus of the present invention, a continuous and highly precise measurement is attainable.
    Type: Grant
    Filed: December 29, 1993
    Date of Patent: July 23, 1996
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Hiroaki Uematsu, Makoto Tsuruoka, Takashi Nakajima, Ken-ichi Chikanari, Misao Yoshimoto, Hiromichi Kobata
  • Patent number: 4935117
    Abstract: A flow through type ion electrode apparatus including a number of interconnectable block structures. Each block structure includes recesses in respective faces thereof, which lead to a through hole extending between the faces. A membrane electrode is located within each block structure so as to communicate with the through hole. A spacer having a through hole therein is inserted in a recess of each of a pair of adjacent block structures to interconnect the adjacent block structures.
    Type: Grant
    Filed: June 23, 1989
    Date of Patent: June 19, 1990
    Assignee: Horiba, Ltd.
    Inventors: Hiroaki Uematsu, Kunio Terada
  • Patent number: 4877492
    Abstract: Method of measuring electrolyte concentration in a urine sample, by preparing a calibrating solution containing ions of the electrolytes to be measured, preparing a diluent containing the same ions, diluting the urine sample with the diluent, measuring the electrolyte in the diluted urine with an electrode using the calibrating solution, and calculating the concentration of electrolyte based on the measured value. Additionally, the concentration of the same electrolytes in a blood sample can be measured without dilution, using the same calibrating solution.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: October 31, 1989
    Assignee: Horiba, Ltd.
    Inventors: Hiroaki Uematsu, Shinji Imanishi
  • Patent number: 4629744
    Abstract: A composition for use in a chloride ion electrode is provided herein. This composition is made up of a mixture of an epoxy resin, a vinyl chloride resin, one or more solvents, a quaternary ammonium salt and hardening agents for setting said epoxy resin; wherein said epoxy resin and the vinyl chloride resin is used at a ratio of 8:1 to 1:2 by weight. The present invention also relates to a response membrane produced from said composition and a method for producing the response membrane by setting or hardening the aforementioned composition. When the response membrane is used in the chloride ion selective electrode, it is capable of measuring a sample containing blood or protein and by use of the response membrane, it is possible to selectively determine chloride ions in a sample with a high degree of accuracy.
    Type: Grant
    Filed: March 20, 1985
    Date of Patent: December 16, 1986
    Assignee: Horibe, Ltd.
    Inventors: Hiroaki Uematsu, Takeshi Kohno, Takeshi Miyazaki
  • Patent number: 4626512
    Abstract: A standard solution for simultaneously calibrating a plurality of ion electrodes for determining a plurality of ion electrodes for determining a plurality of ions including at least potassium ions and calcium ions in blood, the improvement wherein the concentration of the standard solution for a potassium ion electrode and a calcium ion electrode is adjusted in accordance with the following equations: ##EQU1## As for potassium ion,C=C.sub.o .multidot.10.sup.-.DELTA.E/60As for calcium ion,C=C.sub.o .multidot.10.sup.-.DELTA.E/30As for potassium ion,A=-0.130 to -0.065As for calcium ion,A=-0.240 to -0.172whereinE: is the potential difference when an ionic strength of 150 mM is used as the standard;.mu.: is the ionic strength;C.sub.o : is the calibrated concentration;C: is the concentration of reagent added; andA: is the correction factor.
    Type: Grant
    Filed: May 22, 1985
    Date of Patent: December 2, 1986
    Assignee: Horiba, Ltd.
    Inventors: Narihiro Oku, Seiji Usui, Hiroaki Uematsu, Takeshi Kohno
  • Patent number: 4551222
    Abstract: A flow through system liquid membrane type electrode used for measuring a specific ion concentration in a flowing liquid sample. A cylindrical membrane holding member which is flat at one side surface, holds a sheet-like liquid membrane, the liquid membrane facing a liquid sample passage formed in a synthetic resin block, thereby to form a strong junction between the liquid membrane and the sample passage.
    Type: Grant
    Filed: June 19, 1984
    Date of Patent: November 5, 1985
    Assignee: Horiba, Ltd.
    Inventors: Hiroaki Uematsu, Junji Aoki
  • Patent number: 4519890
    Abstract: A flow system glass electrode in use for pH measurement, which houses the glass electrode body in a resin block to improve an impact resistance, the glass electrode body being sealed by a packing to be small-sized and improve the degree of freedom in the direction of the use, sample flow tubes each being equal in an inner diameter to a response film and separate from the glass electrode body in order to eliminate stagnation of a sample liquid, enable the measurement of a minute sample, and facilitate manufacture and assembly of the electrode, the sample flow tubes being connected with a liquid inlet and a liquid outlet at the glass electrode body through couplings respectively.
    Type: Grant
    Filed: May 24, 1984
    Date of Patent: May 28, 1985
    Assignee: Horiba, Ltd.
    Inventors: Hiroaki Uematsu, Junji Aoki, Narihiro Oku