Patents by Inventor Hirofumi MATSUNAGA

Hirofumi MATSUNAGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240305924
    Abstract: A speaker includes a speaker unit and a holding member that holds the speaker unit. Here, the holding member is made of a resilient material and has a holding portion that holds the speaker unit and an attachment portion that is provided integrally with the holding portion and is fixed to a rear case.
    Type: Application
    Filed: November 25, 2021
    Publication date: September 12, 2024
    Inventors: Akinori Matsunaga, Hirofumi Onohara, Tomohisa Yoshida
  • Patent number: 10597375
    Abstract: A novel ?-halogen-substituted thiophene compound or a pharmacologically acceptable salt thereof, which has a potent LPA receptor-antagonist activity and is useful as a medicament is provided. A compound represented by the general formula (I) wherein A represents, a phenyl ring, a thiophene ring, or an isothiazole ring; R1 is the same or different, and represents a halogen atom, or a C1-C3 alkyl group; R2 represents a hydrogen atom, or a C1-C6 alkyl group; p represents an integer of 0 to 5; V represents CR3 wherein R3 represents a hydrogen atom, an amino group, a nitro group, or a C1-C3 alkoxy group, or V represents a nitrogen atom; and X represents a halogen atom, or a salt thereof.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: March 24, 2020
    Assignee: UBE INDUSTRIES, LTD.
    Inventors: Noriaki Iwase, Hiroshi Nishida, Makoto Okudo, Masaaki Ito, Shigeyuki Kono, Masaaki Matoyama, Shigeru Ushiyama, Eiji Okanari, Hirofumi Matsunaga, Kenji Nishikawa, Tomio Kimura
  • Publication number: 20180360803
    Abstract: The present invention provides the pharmaceutical use of LPA1 antagonists, for example, ?-halogenated thiophene compounds having a specific structure or pharmacologically acceptable salts thereof, as drugs for the treatment and/or prevention of NASH. A pharmaceutical composition for the treatment and/or prevention of NASH includes, as an active ingredient, an LPA1 antagonist, for example, a compound represented by the general formula (I): wherein R1 is a hydrogen atom or a methoxy group, R2 is a hydrogen atom or a C1-C6 alkyl group, X is a halogen atom, and A is a group selected from the group consisting of groups: , or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 20, 2018
    Applicant: UBE INDUSTRIES, LTD.
    Inventors: Kenji NISHIKAWA, Hirofumi MATSUNAGA, Yuuko SHINOHARA, Eiji OKANARI, Shigeru USHIYAMA, Shinpei NONOUCHI
  • Publication number: 20180258062
    Abstract: A novel ?-halogen-substituted thiophene compound or a pharmacologically acceptable salt thereof, which has a potent LPA receptor-antagonist activity and is useful as a medicament is provided. A compound represented by the general formula (I) wherein A represents, a phenyl ring, a thiophene ring, or an isothiazole ring; R1 is the same or different, and represents a halogen atom, or a C1-C3 alkyl group; R2 represents a hydrogen atom, or a C1-C6 alkyl group; p represents an integer of 0 to 5; V represents CR3 wherein R3 represents a hydrogen atom, an amino group, a nitro group, or a C1-C3 alkoxy group, or V represents a nitrogen atom; and X represents a halogen atom, or a salt thereof.
    Type: Application
    Filed: May 8, 2018
    Publication date: September 13, 2018
    Applicant: UBE INDUSTRIES, LTD.
    Inventors: Noriaki IWASE, Hiroshi NISHIDA, Makoto OKUDO, Masaaki ITO, Shigeyuki KONO, Masaaki MATOYAMA, Shigeru USHIYAMA, Eiji OKANARI, Hirofumi MATSUNAGA, Kenji NISHIKAWA, Tomio KIMURA
  • Patent number: 10023554
    Abstract: The invention provides a novel ?-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a medicament. The salt is represented by the general formula (I): (wherein R is a hydrogen atom or a methoxy group; X is a halogen atom; A is selected from the group consisting of: M is an alkali metal or an alkaline earth metal; and n is 1 when M is an alkali metal and is 2 when M is an alkaline earth metal).
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: July 17, 2018
    Assignee: UBE INDUSTRIES, LTD.
    Inventors: Noriaki Iwase, Hiroshi Nishida, Makoto Okudo, Masaaki Ito, Shigeyuki Kono, Masaaki Matoyama, Shigeru Ushiyama, Eiji Okanari, Hirofumi Matsunaga, Kenji Nishikawa, Tomio Kimura
  • Patent number: 10000463
    Abstract: A novel ?-halogen-substituted thiophene compound or a pharmacologically acceptable salt thereof, which has a potent LPA receptor-antagonist activity and is useful as a medicament is provided.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: June 19, 2018
    Assignee: UBE INDUSTRIES, LTD.
    Inventors: Noriaki Iwase, Hiroshi Nishida, Makoto Okudo, Masaaki Ito, Shigeyuki Kono, Masaaki Matoyama, Shigeru Ushiyama, Eiji Okanari, Hirofumi Matsunaga, Kenji Nishikawa, Tomio Kimura
  • Publication number: 20170158663
    Abstract: The invention provides a novel ?-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a medicament. The salt is represented by the general formula (I): (wherein R is a hydrogen atom or a methoxy group; X is a halogen atom; A is selected from the group consisting of: ;M is an alkali metal or an alkaline earth metal; and n is 1 when M is an alkali metal and is 2 when M is an alkaline earth metal).
    Type: Application
    Filed: June 26, 2015
    Publication date: June 8, 2017
    Applicant: UBE INDUSTRIES, LTD.
    Inventors: Noriaki IWASE, Hiroshi NISHIDA, Makoto OKUDO, Masaaki ITO, Shigeyuki KONO, Masaaki MATOYAMA, Shigeru USHIYAMA, Eiji OKANARI, Hirofumi MATSUNAGA, Kenji NISHIKAWA, Tomio KIMURA
  • Publication number: 20150376160
    Abstract: A novel ?-halogen-substituted thiophene compound or a pharmacologically acceptable salt thereof, which has a potent LPA receptor-antagonist activity and is useful as a medicament is provided. A compound represented by the general formula (I) wherein A represents, a phenyl ring, a thiophene ring, or an isothiazole ring; R1 is the same or different, and represents a halogen atom, or a C1-C3 alkyl group; R2 represents a hydrogen atom, or a C1-C6 alkyl group; p represents an integer of 0 to 5; V represents CR3 wherein R3 represents a hydrogen atom, an amino group, a nitro group, or a C1-C3 alkoxy group, or V represents a nitrogen atom; and X represents a halogen atom, or a salt thereof.
    Type: Application
    Filed: June 26, 2015
    Publication date: December 31, 2015
    Applicant: UBE INDUSTRIES, LTD.
    Inventors: Noriaki IWASE, Hiroshi NISHIDA, Makoto OKUDO, Masaaki ITO, Shigeyuki KONO, Masaaki MATOYAMA, Shigeru USHIYAMA, Eiji OKANARI, Hirofumi MATSUNAGA, Kenji NISHIKAWA, Tomio KIMURA