Patents by Inventor Hirohide Nakaguma

Hirohide Nakaguma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230220321
    Abstract: The object is achieved by an organic-inorganic composite dispersion liquid comprising organic-inorganic composite particles (X) which are formed of a polymer (P) of a monomer including a (meth)acrylamide-based monomer (a) and one or more inorganic materials (B) selected from a water-swellable clay mineral or silica in a three-dimensional network and are dispersed in an aqueous medium (C), in which an average particle diameter of the organic-inorganic composite particles (X) is 100 nm or more.
    Type: Application
    Filed: March 3, 2023
    Publication date: July 13, 2023
    Applicant: FUJIFILM Corporation
    Inventors: Naoto SAKURAI, Hirohide Nakaguma, Tetsuo Takada
  • Patent number: 11441120
    Abstract: The present invention is to provide a cell culture substrate including a block polymer including a segment having a lower critical solution temperature and a hydrophobic segment, the cell culture substrate further including an adhesive matrix, in which the adhesive matrix is an extracellular matrix and/or an adhesive synthetic matrix. Furthermore, the invention is to provide a cell culture substrate in which the extracellular matrix is at least one selected from laminin, fibronectin, vitronectin, cadherin, and fragments thereof, and/or the adhesive synthetic matrix is poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] or an oligopeptide-carrying polymer.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: September 13, 2022
    Assignee: FUJIFILM Corporation
    Inventors: Hirohide Nakaguma, Tetsuo Takada, Ayako Isshiki
  • Patent number: 11427803
    Abstract: The present invention is to provide a cell culture substrate including a block polymer including a segment having a lower critical solution temperature and a hydrophobic segment, in which the segment having a lower critical solution temperature has a degree of polymerization of 400 to 10,000. Also provided is a cell culture substrate, in which the hydrophobic segment is obtainable by polymerizing a monomer having a particular structure. Also provided is a cell culture substrate being laminated on a supporting medium. Furthermore, a cell culture substrate having an average film thickness of 1,000 nm or less is provided.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: August 30, 2022
    Assignee: Fujifilm Corporation
    Inventors: Hirohide Nakaguma, Ayako Isshiki
  • Patent number: 11306286
    Abstract: The present invention is to provide a cell culture substrate including a block polymer including a segment having a lower critical solution temperature and a hydrophobic segment, the cell culture substrate further including an adhesive matrix, in which the adhesive matrix is an extracellular matrix and/or an adhesive synthetic matrix. Furthermore, the invention is to provide a cell culture substrate in which the extracellular matrix is at least one selected from laminin, fibronectin, vitronectin, cadherin, and fragments thereof, and/or the adhesive synthetic matrix is poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] or an oligopeptide-carrying polymer.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: April 19, 2022
    Assignee: DIC Corporation
    Inventors: Hirohide Nakaguma, Tetsuo Takada, Ayako Isshiki
  • Publication number: 20190367870
    Abstract: The present invention is to provide a cell culture substrate including a block polymer including a segment having a lower critical solution temperature and a hydrophobic segment, in which the segment having a lower critical solution temperature has a degree of polymerization of 400 to 10,000. Also provided is a cell culture substrate, in which the hydrophobic segment is obtainable by polymerizing a monomer having a particular structure. Also provided is a cell culture substrate being laminated on a supporting medium. Furthermore, a cell culture substrate having an average film thickness of 1,000 nm or less is provided.
    Type: Application
    Filed: December 12, 2017
    Publication date: December 5, 2019
    Inventors: Hirohide Nakaguma, Ayako Isshiki
  • Publication number: 20190338243
    Abstract: The present invention is to provide a cell culture substrate including a block polymer including a segment having a lower critical solution temperature and a hydrophobic segment, the cell culture substrate further including an adhesive matrix, in which the adhesive matrix is an extracellular matrix and/or an adhesive synthetic matrix. Furthermore, the invention is to provide a cell culture substrate in which the extracellular matrix is at least one selected from laminin, fibronectin, vitronectin, cadherin, and fragments thereof, and/or the adhesive synthetic matrix is poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] or an oligopeptide-carrying polymer.
    Type: Application
    Filed: December 12, 2017
    Publication date: November 7, 2019
    Inventors: Hirohide Nakaguma, Tetsuo Takada, Ayako Isshiki
  • Publication number: 20150190563
    Abstract: Provided is: a resin compound having an immobilized sugar chain, obtained by reacting a an epoxy-group-containing compound (B) with a hydrophilic resin (A), followed by reacting an amino-group-containing compound (C) therewith, and then reacting a sugar therewith; a virus-removal-polymer substrate obtained by coating the resin compound on a polymer support to immobilize a sugar chain that can adsorb a virus; and a biocompatible material using the resin compound.
    Type: Application
    Filed: July 19, 2013
    Publication date: July 9, 2015
    Inventors: Hirohide Nakaguma, Naoto Sakurai, Naoya Ikushima, Tetsuro Suzuki
  • Patent number: 7649041
    Abstract: An aqueous coating composition comprising a hydrophilic cationic polymer having an amino group (A), nonionic polyalcohol (B), a tri- or more valent silane compound (C), and water (D). According to the aqueous coating composition of the present invention, it is possible to produce an organic and inorganic hybrid coating film having a high degree of hardness and excellent abrasion resistance in relative mild production conditions by a simple method.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: January 19, 2010
    Assignees: DIC Corporation, Kawamura Institute of Chemical Research
    Inventors: Hirohide Nakaguma, Ren-Hua Jin, Seungtaeg Lee
  • Publication number: 20090047436
    Abstract: The object of the present invention is to provide an aqueous coating composition including: an aqueous dispersion of a cationic resin (A); a metal alkoxide or a condensation product thereof (B); and an acid catalyst (C), and an organic-inorganic composite coating film wherein particles of a cationic resin (A) are dispersed in a matrix of a metal oxide (B?).
    Type: Application
    Filed: December 12, 2006
    Publication date: February 19, 2009
    Applicant: DIC CORPORATION
    Inventors: Hirohide Nakaguma, Hiroyuki Buei, Ren-Hua Jin, Kazunori Tanaka, Kenji Nagao
  • Publication number: 20080248281
    Abstract: The organic-inorganic composite coating film of the present invention is a composite coating film wherein a complex having a polyamine segment is combined in a matrix composed of an inorganic oxide, and has a fine pore pattern on the surface. The aqueous coating composition of the present invention includes a copolymer having a polyamine segment, a metal alkoxide, and an aqueous medium.
    Type: Application
    Filed: July 27, 2005
    Publication date: October 9, 2008
    Applicants: DAINIPPON INK & CHEMICALS, INC, KAWAMURA INSTITUTE OF CHEMICAL RESEARCH
    Inventors: Hirohide Nakaguma, Ren-Hua Jin, Seungtaeg Lee