Patents by Inventor Hirohide Yoshikawa

Hirohide Yoshikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE ASSOCIATED WITH LIVER CANCER, AND METHOD FOR DETERMINATION OF THE RISK OF ACQUIRING LIVER CANCER
    Publication number: 20110218121
    Abstract: Provided are a method for detecting early-stage liver cancer and determining a risk of liver cancer by using blood collected from a patient with imposing a less burden on the patient; and a gene marker, a probe, a primer, and a reagent kit that can be used in the detection. A marker for diagnosis of acquiring liver cancer includes a polynucleotide that can detect all of the following methylated genes and a gene region: (1) human SALL3c gene, (2) human ECEL1 gene, and (3) SEQ ID NO: 6 (NT_037622.5, 1393863-1395863).
    Type: Application
    Filed: October 29, 2008
    Publication date: September 8, 2011
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Takeaki Ishizawa, Norihiro Kokudo, Hirohide Yoshikawa, Yuko Shikauchi, Yaeko Murase
  • SOCS-1 GENE METHYLATION IN CANCER
    Publication number: 20100297655
    Abstract: Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
    Type: Application
    Filed: July 6, 2010
    Publication date: November 25, 2010
    Applicant: The Johns Hopkins University
    Inventors: James G. Herman, Hirohide Yoshikawa, Curtis C. Harris
  • SOCS-1 gene methylation in cancer
    Patent number: 7749709
    Abstract: Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
    Type: Grant
    Filed: February 22, 2008
    Date of Patent: July 6, 2010
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: James G. Herman, Hirohide Yoshikawa, Curtis C. Harris
  • SOCS-1 Gene Methylation in Cancer
    Publication number: 20080213782
    Abstract: Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
    Type: Application
    Filed: February 22, 2008
    Publication date: September 4, 2008
    Inventors: James. G. Herman, Hirohide Yoshikawa, Curtis C. Harris
  • SOCS-1 GENE METHYLATION IN CANCER
    Publication number: 20080076117
    Abstract: Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
    Type: Application
    Filed: April 15, 2002
    Publication date: March 27, 2008
    Inventors: James G. Herman, Hirohide Yoshikawa, Curtis C. Harris
  • SOCS-1 gene methylation in cancer
    Patent number: 7348139
    Abstract: Methods are provided for identifying a cell exhibiting unregulated growth associated with methylation-silenced transcription of a suppressor of cytokine signaling (SOCS)/cytokine-inducible SH2 protein (CIS) family member (SOCS/CIS) gene such as the SOCS-1 gene. In addition, methods of treating a cancer patient, wherein cancer cells in the patient exhibit methylation-silenced transcription of SOCS/CIS gene such as a SOCS-1 gene, are provided, as are reagents for practicing such methods.
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: March 25, 2008
    Assignee: The Johns Hopkins University School of Medicine
    Inventors: James G. Herman, Hirohide Yoshikawa, Curtis C. Harris