Patents by Inventor Hirohiko Komatsu

Hirohiko Komatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-platelet aggregating agent
    Patent number: 5227395
    Abstract: The use of 1-phenoxycarbonyl-2-pyrrolidinone derivatives as an anti-platelet aggregating agent. The derivatives are of the formula ##STR1## wherein R is a C.sub.1 -C.sub.6 alkyl group, a C.sub.1 -C.sub.6 alkoxy group, a nitro group or a halogen atom and n is 0, 1 or 2.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: July 13, 1993
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Hirohiko Komatsu, Einosuke Sakurai, Fumiko Hamaguchi, Tatsuo Nagasaka
  • Rhodanine derivatives and pharmaceutical compositions
    Patent number: 4897406
    Abstract: Disclosed are a compound of the formula ##STR1## wherein R.sup.1 is C.sub.1 -C.sub.6 alkyl or a group --(CH.sub.2).sub.n COOR.sup.3 in which n is an integer of 1 to 4 and R.sup.3 is hydrogen or C.sub.1 -C.sub.6 alkyl, and R.sup.2 is a group --CH.dbd.CH--R.sup.4 or --CH.sub.2 --CH.sub.2 --R.sup.4 in which R.sup.4 is substituted or unsubstituted phenyl or a substituted or unsubstituted 5-membered heterocyclic group, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient. The compounds have an excellent chemical mediator inhibitory activity.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: January 30, 1990
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Hitoshi Inoue, Hiroyasu Koyama, Reiko Kubota, Hirohiko Komatsu