Abstract: A diffractive optical device includes at least one diffractive optical element. The diffractive optical element generates light having a first order and light having a second order from a laser beam input to the diffractive optical element. The diffractive optical element includes a first phase pattern and a second phase pattern. The first phase pattern converts the laser beam into a line beam. The second phase pattern diffracts the laser beam in a short axis direction of the line beam to generate the light having the first order and the light having the second order. A first focal plane of the light having the first order is located at a position different from a second focal plane of the light having the second order on an optical axis of the laser beam.

Abstract: A diffractive optical device includes at least one diffractive optical element. The diffractive optical element generates light having a first order and light having a second order from a laser beam input to the diffractive optical element. The diffractive optical element includes a first phase pattern and a second phase pattern. The first phase pattern converts the laser beam into a line beam. The second phase pattern diffracts the laser beam in a short axis direction of the line beam to generate the light having the first order and the light having the second order. A first focal plane of the light having the first order is located at a position different from a second focal plane of the light having the second order on an optical axis of the laser beam.

Abstract: Embodiments of the present invention provide a topical agent that is a preparation containing hydrolyzed silk. The topical agent is applied to a wound site for use in wound healing, an thus, an object thereof being to have an effect of promoting wound healing and to satisfy practical application conditions with regard to an irritative property, stability, handling ease, and the like. The topical agent contains hydrolyzed fibroin, an oil-based component, and a water-based component. The topical agent according to the embodiments of the present invention is preferably an ointment or a cream. The topical agent contains hydrolyzed fibroin as an active ingredient in an amount of 1 to 40 wt %, and preferably does not contain a surfactant.