Patents by Inventor Hirokazu Kubo
Hirokazu Kubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11900574Abstract: The image processing system includes a scanner, a pixelated photon detector (PPD), and at least one processor. The at least one processor displays a setting screen on a display unit. The setting screen is a screen for setting an identification range that is a range of gradation to be identified. The at least one processor displays a second image obtained by converting a first image on the display unit. The second image is an image obtained by converting the first image based on at least the identification range. The first image is generated based on an intensity signal of light detected by a PPD and a scanning position by the scanner.Type: GrantFiled: July 5, 2022Date of Patent: February 13, 2024Assignee: Evident CorporationInventors: Kanako Isono, Hirokazu Kubo
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Publication number: 20220335582Abstract: The image processing system includes a scanner, a pixelated photon detector (PPD), and at least one processor. The at least one processor displays a setting screen on a display unit. The setting screen is a screen for setting an identification range that is a range of gradation to be identified. The at least one processor displays a second image obtained by converting a first image on the display unit. The second image is an image obtained by converting the first image based on at least the identification range. The first image is generated based on an intensity signal of light detected by a PPD and a scanning position by the scanner.Type: ApplicationFiled: July 5, 2022Publication date: October 20, 2022Applicant: OLYMPUS CORPORATIONInventors: Kanako ISONO, Hirokazu KUBO
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Patent number: 10379328Abstract: A confocal scanner into which light from a light source is introduced via a multimode optical fiber includes: a disk unit that includes a rotary disk; and an optical system that irradiates the rotary disk with light from an emission end face of the optical fiber. The optical system includes an element that changes a size in which the emission end face of the optical fiber is projected onto the rotary disk.Type: GrantFiled: November 16, 2016Date of Patent: August 13, 2019Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Patent number: 10338366Abstract: A confocal scanner into which light from a light source is introduced via a multimode optical fiber includes: a disk unit that includes a rotary disk; and an optical system that irradiates the rotary disk with light from an emission end face of the optical fiber. The optical system includes an element that changes a size in which the emission end face of the optical fiber is projected onto the rotary disk.Type: GrantFiled: November 16, 2016Date of Patent: July 2, 2019Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Patent number: 10209504Abstract: Provided is a light detecting device including: a light path branching unit that branches a single detection light path of fluorescence from a specimen, into a plurality of branched light paths; a plurality of light detectors that are provided to the respective branched light paths branched by the light path branching unit and that include an SSPD or Geiger mode APD to detect the fluorescence; and a signal adder that generates a single image signal in accordance with the detection signals outputted from the plurality of light detectors.Type: GrantFiled: March 27, 2018Date of Patent: February 19, 2019Assignees: OLYMPUS CORPORATION, NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, OSAKA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Hirokazu Kubo, Shigehito Miki, Hirotaka Terai, Taro Yamashita, Tokuko Haraguchi, Yasushi Hiraoka, Masataka Kinjo
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Publication number: 20180284413Abstract: Provided is a light detecting device including: a light path branching unit that branches a single detection light path of fluorescence from a specimen, into a plurality of branched light paths; a plurality of light detectors that are provided to the respective branched light paths branched by the light path branching unit and that include an SSPD or Geiger mode APD to detect the fluorescence; and a signal adder that generates a single image signal in accordance with the detection signals outputted from the plurality of light detectors.Type: ApplicationFiled: March 27, 2018Publication date: October 4, 2018Applicants: OLYMPUS CORPORATION, NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY, OSAKA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYInventors: Hirokazu KUBO, Shigehito MIKI, Hirotaka TERAI, Taro YAMASHITA, Tokuko HARAGUCHI, Yasushi HIRAOKA, Masataka KINJO
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Patent number: 10067329Abstract: A microscope apparatus provided with: a disk unit obtained by integrally forming a pinhole array disk in which pinholes are arranged and a microlens array disk in which microlenses are arranged; a dichroic mirror focusing illumination light that has been transmitted through the microlenses of the disk unit, on the corresponding pinholes and splitting off fluorescence from a specimen that has passed through the pinholes in the reverse direction from the illumination light; an objective lens radiating the illumination light that has passed through the pinholes onto the specimen and focusing the fluorescence from the specimen on the pinholes; an illumination-light-axis adjustment mechanism adjusting the position and the angle of the optical axis of the illumination light; an installation-angle adjustment mechanism adjusting the installation angle of the disk unit; and a unit insertion/removal mechanism removably supporting the disk unit onto the optical axis of the illumination light.Type: GrantFiled: April 24, 2017Date of Patent: September 4, 2018Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Patent number: 10018822Abstract: By using a PPD as a detector, photon count loss is reduced to the utmost, and the incident light-intensity range in which light can be detected is widened. Provided is a laser microscope apparatus including an objective lens that collects return light from a specimen; a collimator lens that converts the return light collected by the objective lens into a substantially collimated beam, a PPD including a plurality of pixels that detect the return light converted to a substantially collimated beam by the collimator lens; and a controller that makes the beam diameter of the return light incident on the PPD substantially equal to an effective detection area of the PPD, formed by the plurality of pixels.Type: GrantFiled: May 27, 2015Date of Patent: July 10, 2018Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Publication number: 20180188518Abstract: A laser microscope apparatus including a light source that generates a laser light serving as excitation light; a mirror scanner that scans the laser light onto a specimen; an objective lens that radiates the laser light onto the specimen and that collects light from the specimen; a uniform-illumination element that causes the light from the specimen collected by the objective lens to have a substantially uniform intensity distribution; and a photodetector that detects the light uniformized by the uniform-illumination element in a Geiger mode and that has a detector including a plurality of detection elements, the detector outputting a sum of outputs from the plurality of detection elements as an intensity signal.Type: ApplicationFiled: February 27, 2018Publication date: July 5, 2018Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Patent number: 10001632Abstract: A laser microscope apparatus including: a scanning unit that scans laser light on a sample; an objective lens that collects observation light from the sample; a photo-detection unit that has a light-receiving surface formed of an array of a plurality of detecting elements capable of detecting a single photon, that receives the observation light incident on the light-receiving surface, and that outputs intensity signals having intensities corresponding to the amounts of the received observation light; an image generating unit that generates an image on the basis of the intensities of the intensity signals and scanning positions of the laser light; a processor for notifying a user when the intensity signals used to generate the image include intensity signals having intensities equal to or larger than a predetermined threshold that is set according to the beam diameter of the observation light incident on the light-receiving surface.Type: GrantFiled: January 27, 2016Date of Patent: June 19, 2018Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Publication number: 20180113291Abstract: Provided is a laser microscope that includes a beam-scanning unit that scans a sample with a laser beam emitted from a laser light source; two or more photodetectors each formed of a superconducting nanowire single photon detector that detects a beam returning from the sample as a result of the scanning of the laser beam by the beam-scanning unit; and one cryocooler that cools the photodetectors. The photodetectors respectively detect beams that have passed through different channels.Type: ApplicationFiled: October 10, 2017Publication date: April 26, 2018Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Publication number: 20180012701Abstract: A method for producing an RFeB system sintered magnet according to the present invention includes: a process (S1) of preparing a lump of HDDR-treated raw material alloy that contains a polycrystalline substance including crystal grains having an average grain size of 1 ?m or less in terms of an equivalent circle diameter calculated from an electron micrograph image, by an HDDR treatment including steps of heating a lump of RFeB system alloy containing 26.5 to 29.5% by weight of the rare-earth element R, in a hydrogen atmosphere at a temperature between 700 and 1,000° C., and changing the atmosphere to vacuum while maintaining the temperature within a range from 750 to 900° C.; a process (S2) of preparing a lump of raw material alloy having a high rare-earth content by heating the lump of HDDR-treated raw material alloy at a temperature between 700 and 950° C.Type: ApplicationFiled: January 8, 2016Publication date: January 11, 2018Applicant: INTERMETALLICS CO., LTD.Inventors: Masato SAGAWA, Yasuhiro UNE, Hirokazu KUBO, Satoshi SUGIMOTO, Masashi MATSUURA, Michihide NAKAMURA
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Publication number: 20170336611Abstract: A microscope apparatus provided with: a disk unit obtained by integrally forming a pinhole array disk in which pinholes are arranged and a microlens array disk in which microlenses are arranged; a dichroic mirror focusing illumination light that has been transmitted through the microlenses of the disk unit, on the corresponding pinholes and splitting off fluorescence from a specimen that has passed through the pinholes in the reverse direction from the illumination light; an objective lens radiating the illumination light that has passed through the pinholes onto the specimen and focusing the fluorescence from the specimen on the pinholes; an illumination-light-axis adjustment mechanism adjusting the position and the angle of the optical axis of the illumination light; an installation-angle adjustment mechanism adjusting the installation angle of the disk unit; and a unit insertion/removal mechanism removably supporting the disk unit onto the optical axis of the illumination light.Type: ApplicationFiled: April 24, 2017Publication date: November 23, 2017Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Publication number: 20170278604Abstract: An RFeB system sintered magnet which does not contain a heavy rare-earth element RH (Dy, Tb and Ho) in a practically effective amount and yet is suited for applications in which the magnet undergoes a temperature increase during its use. The RFeB system sintered magnet contains at least one element selected from the group consisting of Nd and Pr as a rare-earth element R in addition to Fe and B while containing none of Dy, Tb and Ho, the magnet having a temperature characteristic value t(100-23) which satisfies ?0.58<t(100-23)<0, where t(100-23) is defined by the following equation: t ( 100 - 23 ) = H cj ? ( 100 ) - H cj ? ( 23 ) ( 100 - 23 ) × H cj ? ( 23 ) × 100 using Hcj(23) which is the value of the coercivity at a temperature of 23° C. and Hcj(100) which is the value of the coercivity at a temperature of 100° C.Type: ApplicationFiled: August 18, 2015Publication date: September 28, 2017Applicant: INTERMETALLICS CO., LTD.Inventors: Yasuhiro UNE, Hirokazu KUBO, Masato SAGAWA, Satoshi SUGIMOTO, Masashi MATSUURA, Michihide NAKAMURA
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Publication number: 20170153433Abstract: A confocal scanner into which light from a light source is introduced via a multimode optical fiber includes: a disk unit that includes a rotary disk; and an optical system that irradiates the rotary disk with light from an emission end face of the optical fiber. The optical system includes an element that changes a size in which the emission end face of the optical fiber is projected onto the rotary disk.Type: ApplicationFiled: November 16, 2016Publication date: June 1, 2017Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Publication number: 20160231547Abstract: A laser microscope apparatus including: a scanning unit that scans laser light on a sample; an objective lens that collects observation light from the sample; a photo-detection unit that has a light-receiving surface formed of an array of a plurality of detecting elements capable of detecting a single photon, that receives the observation light incident on the light-receiving surface, and that outputs intensity signals having intensities corresponding to the amounts of the received observation light; an image generating unit that generates an image on the basis of the intensities of the intensity signals and scanning positions of the laser light; a processor for notifying a user when the intensity signals used to generate the image include intensity signals having intensities equal to or larger than a predetermined threshold that is set according to the beam diameter of the observation light incident on the light-receiving surface.Type: ApplicationFiled: January 27, 2016Publication date: August 11, 2016Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Patent number: 9356413Abstract: Provided is a laser source apparatus including a single laser source that emits an ultrashort-pulse laser beam; a wavelength conversion mechanism that generates a plurality of pulsed laser beams having different wavelengths by converting at least a part of wavelength of the ultrashort-pulse laser beam; a dispersion adjusting section that adjusts the amount of frequency dispersion for each of the pulsed laser beams; and an introducing optics that emits the plurality of pulsed laser beams whose frequency dispersion amounts are adjusted by the dispersion adjusting section. The dispersion adjusting section adjusts the amount of frequency dispersion for each of the pulsed laser beams so that each of the pulsed laser beams introduced to the irradiation optics of the optical apparatus from the introducing optics to excite a specimen is close to a substantially Fourier-transform-limited pulse.Type: GrantFiled: September 24, 2012Date of Patent: May 31, 2016Assignee: OLYMPUS CORPORATIONInventor: Hirokazu Kubo
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Publication number: 20160027564Abstract: A method for producing an RFeB system sintered magnet with the main phase grains having a grain size of 1 ?m or less with a considerably equal grain size, including: preparing a shaped body oriented by a magnetic field and sintering the shaped body, wherein the shaped body is prepared using an alloy powder of an RFeB material having a particle size distribution with an average value of 1 ?m or less in terms of a circle-equivalent diameter determined from a microscope image, the alloy powder obtained by pulverizing coarse particles having fine crystal grain, each coarse particle having grains of the RFeB material formed inside, the crystal grains having a crystal grain size distribution with an average value of 1 ?m or less in terms of the circle-equivalent diameter determined from a microscope image, and 90% by area or more of the crystal grains being separated from each other.Type: ApplicationFiled: March 12, 2014Publication date: January 28, 2016Applicant: INTERMETALLICS CO., LTD.Inventors: Yasuhiro UNE, Hirokazu KUBO, Masato SAGAWA, Satoshi SUGIMOTO, Masashi MATSUURA, Michihide NAKAMURA
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Publication number: 20150362715Abstract: By using a PPD as a detector, photon count loss is reduced to the utmost, and the incident light-intensity range in which light can be detected is widened. Provided is a laser microscope apparatus including an objective lens that collects return light from a specimen; a collimator lens that converts the return light collected by the objective lens into a substantially collimated beam, a PPD including a plurality of pixels that detect the return light converted to a substantially collimated beam by the collimator lens; and a controller that makes the beam diameter of the return light incident on the PPD substantially equal to an effective detection area of the PPD, formed by the plurality of pixels.Type: ApplicationFiled: May 27, 2015Publication date: December 17, 2015Applicant: OLYMPUS CORPORATIONInventor: Hirokazu KUBO
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Patent number: 8294985Abstract: Observation is performed using bright, clear multiphoton fluorescence images produced by efficiently generating a multiphoton excitation effect, without the need for a complex interference film structure. The invention employs a laser microscope apparatus including a first dichroic mirror that reflects visible laser light guided via a first light path and that transmits IR pulsed laser light guided via a second light path to combine the first light path and the second light path; an XY galvanometer mirror that scans the laser light from the first dichroic mirror on a specimen; an objective lens that irradiates the specimen with the scanned laser light and that collects fluorescence produced in the specimen; a second dichroic mirror that reflects the visible laser light and transmits the fluorescence from the specimen; and a detection unit that detects the fluorescence transmitted through the second dichroic mirror.Type: GrantFiled: September 29, 2009Date of Patent: October 23, 2012Assignee: Olympus CorporationInventors: Hiroshi Sasaki, Hirokazu Kubo