Patents by Inventor Hirokazu Nagaoka

Hirokazu Nagaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230148041
    Abstract: A small transistor type sensor capable of detecting a specific compound such as oxytocin is provided. The transistor type sensor includes a detection electrode that detects a compound by capturing the compound, and a field effect transistor that has a gate electrode connected to the detection electrode, wherein a surface of the detection electrode is provided with a film of a molecularly imprinted polymer having a space to which the compound is allowed to bond.
    Type: Application
    Filed: October 13, 2022
    Publication date: May 11, 2023
    Applicants: THE UNIVERSITY OF TOKYO, JNC CORPORATION
    Inventors: Tsuyoshi MINAMI, Qi ZHOU, Yusuke YAMANASHI, Katsumasa NAKAHARA, Hirokazu NAGAOKA
  • Patent number: 9714942
    Abstract: It is intended to provide a detection method and a determination method for detection target capable of detecting and determining a detection target promptly and simply with high accuracy at low cost. The detection method includes the steps of: mixing a first conjugate 10 in which a first substance containing a stimulus-responsive polymer 11 and a particulate magnetic substance 19 is conjugated to a first antibody 13 against a detection target 50 with a sample; applying a magnetic force after placing the resulting mixture in a condition capable of aggregating the stimulus-responsive polymer 11; measuring a generated magnetic field; and detecting the detection target 50 based on the degree of increase in the magnetic field after applying the magnetic force.
    Type: Grant
    Filed: December 25, 2008
    Date of Patent: July 25, 2017
    Assignees: JNC CORPORATION, ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA
    Inventors: Toshiya Sawai, Eri Oowada, Hirokazu Nagaoka, Satoru Sugita, Toshiya Ueki
  • Patent number: 9395336
    Abstract: A scanning acoustic tomograph has a water tank which accommodates water, a sample stand which is disposed in the water tank and on which a subject is placed, a first ultrasonic transducer which irradiates ultrasonic waves toward the subject, and a second ultrasonic transducer which receives the ultrasonic waves transmitted through the subject, the first and second ultrasonic transducers are disposed opposed to each other in a vertical direction, and a hydrophilic film is formed on a lower surface side of the sample stand.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: July 19, 2016
    Assignee: Hitachi Power Solutions Co., Ltd.
    Inventors: Takashi Tomita, Hirokazu Nagaoka, Kaoru Kitami, Masafumi Takada
  • Patent number: 9372187
    Abstract: A detection/determination kit with which a substance to be detected or the amount thereof can be rapidly, inexpensively, and easily detected or determined; and a detection/determination method. The kit, which is for detecting a substance to be detected (50) contained in a specimen, comprises: a first compound (10) comprising a first substance including a stimulus-responsive polymer (11) and, bonded to the first substance, a first antibody (13) against the substance (50); and a second compound (20) comprising a second substance (21) which is hydrophilic and, bonded thereto, a second antibody (23) against the substance (50). The first antibody (13) and second antibody (23) can simultaneously combine with the substance (50) at different sites in the substance (50).
    Type: Grant
    Filed: December 25, 2008
    Date of Patent: June 21, 2016
    Assignees: ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA, JNC CORPORATION
    Inventors: Toshiya Sawai, Eri Oowada, Yasunobu Sato, Hirokazu Nagaoka, Satoru Sugita
  • Publication number: 20140318252
    Abstract: A scanning acoustic tomograph has a water tank which accommodates water, a sample stand which is disposed in the water tank and on which a subject is placed, a first ultrasonic transducer which irradiates ultrasonic waves toward the subject, and a second ultrasonic transducer which receives the ultrasonic waves transmitted through the subject, the first and second ultrasonic transducers are disposed opposed to each other in a vertical direction, and a hydrophilic film is formed on a lower surface side of the sample stand.
    Type: Application
    Filed: April 24, 2014
    Publication date: October 30, 2014
    Applicant: Hitachi Power Solutions Co., Ltd.
    Inventors: Takashi TOMITA, Hirokazu NAGAOKA, Kaoru KITAMI, Masafumi TAKADA
  • Patent number: 8815518
    Abstract: Disclosed are a detection/quantification kit and a detection/quantification method for detecting/quantifying an analyte rapidly at a low cost and in a simple manner. Specifically, disclosed is a kit for detecting an analyte in a sample, comprising a first conjugate and a second conjugate, wherein the first conjugate comprises a first substance comprising a stimuli-responsive polymer and a first affinity substance having affinity for the analyte and bound to the first substance, and the second conjugate comprises a second substance carrying an electrical charge and a second affinity substance having affinity for the analyte and bound to the second substance. The first and second affinity substances can bind to different sites on the analyte simultaneously.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: August 26, 2014
    Assignee: JNC Corporation
    Inventors: Hirokazu Nagaoka, Noriyuki Ohnishi, Kageaki Matsui, Satoru Sugita
  • Publication number: 20110014713
    Abstract: A detection/determination kit with which a substance to be detected or the amount thereof can be rapidly, inexpensively, and easily detected or determined; and a detection/determination method. The kit, which is for detecting a substance to be detected (50) contained in a specimen, comprises: a first compound (10) comprising a first substance including a stimulus-responsive polymer (11) and, bonded to the first substance, a first antibody (13) against the substance (50); and a second compound (20) comprising a second substance (21) which is hydrophilic and, bonded thereto, a second antibody (23) against the substance (50). The first antibody (13) and second antibody (23) can simultaneously combine with the substance (50) at different sites in the substance (50).
    Type: Application
    Filed: December 25, 2008
    Publication date: January 20, 2011
    Applicants: ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA, CHISSO CORPORATION
    Inventors: Toshiya Sawai, Eri Oowada, Yasunobu Sato, Hirokazu Nagaoka, Satoru Sugita
  • Publication number: 20100330688
    Abstract: It is intended to provide a detection method and a determination method for detection target capable of detecting and determining a detection target promptly and simply with high accuracy at low cost. The detection method includes the steps of: mixing a first conjugate 10 in which a first substance containing a stimulus-responsive polymer 11 and a particulate magnetic substance 19 is conjugated to a first antibody 13 against a detection target 50 with a sample; applying a magnetic force after placing the resulting mixture in a condition capable of aggregating the stimulus-responsive polymer 11; measuring a generated magnetic field; and detecting the detection target 50 based on the degree of increase in the magnetic field after applying the magnetic force.
    Type: Application
    Filed: December 25, 2008
    Publication date: December 30, 2010
    Applicants: ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA, CHISSO CORPORATION
    Inventors: Toshiya Sawai, Eri Oowada, Hirokazu Nagaoka, Satoru Sugita, Toshiya Ueki
  • Patent number: 7847047
    Abstract: A material which expresses its critical solution temperature even in an aqueous solution containing a buffer or salt, and at the same time, shows small variation width of the critical solution temperature even when concentration of salt or the like contained in water, a buffer liquid or the like is different, interacts with a substance such as a component in the living body and can therefore be used efficiently in the isolation of substances, is provided. A monomer represented by a formula (1) and a thermoresponsive polymer which contains said monomer as a polymerization component.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: December 7, 2010
    Assignee: Chisso Corporation
    Inventors: Hirokazu Nagaoka, Noriyuki Ohnishi, Masaru Eguchi
  • Publication number: 20100062433
    Abstract: Disclosed are a detection/quantification kit and a detection/quantification method for detecting/quantifying an analyte rapidly at a low cost and in a simple manner. Specifically, disclosed is a kit for detecting an analyte in a sample, comprising a first conjugate and a second conjugate, wherein the first conjugate comprises a first substance comprising a stimuli-responsive polymer and a first affinity substance having affinity for the analyte and bound to the first substance, and the second conjugate comprises a second substance carrying an electrical charge and a second affinity substance having affinity for the analyte and bound to the second substance. The first and second affinity substances can bind to different sites on the analyte simultaneously.
    Type: Application
    Filed: June 28, 2007
    Publication date: March 11, 2010
    Applicants: CHISSO CORPORATION, ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA
    Inventors: Hirokazu Nagaoka, Noriyuki Ohnishi, Kageaki Matsui, Satoru Sugita
  • Patent number: 7306640
    Abstract: A vacuum cleaner includes a first dirt separation unit and a second dirt separation unit. The first dirt separation unit has a first inlet port through which a suction air stream including dirt particles is introduced thereinto, and the second dirt separation unit has a second inlet port through which the air stream introduced into the first dirt separation unit is introduced into the second dirt separation. The first and the second inlet port are disposed such that they are not registered with each other. Accordingly, the dirt particles suctioned are separated in two stages, thereby decreasing the possibility of occlusion of a filter and rapid deterioration of a suction force.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: December 11, 2007
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Yoshiki Kuroki, Seiji Yamaguchi, Tomonori Kato, Masashi Okushima, Yuichi Shimizu, Tomomi Mitani, Hiroshi Mori, Toru Odachi, Yoshiaki Onishi, Hidenori Kitamura, Toshifumi Miyahara, Takaaki Ogawa, Hirokazu Nagaoka
  • Publication number: 20070203313
    Abstract: A material which expresses its critical solution temperature even in an aqueous solution containing a buffer or salt, and at the same time, shows small variation width of the critical solution temperature even when concentration of salt or the like contained in water, a buffer liquid or the like is different, interacts with a substance such as a component in the living body and can therefore be used efficiently in the isolation of substances, is provided. A monomer represented by a formula (1) and a thermoresponsive polymer which contains said monomer as a polymerization component.
    Type: Application
    Filed: February 27, 2007
    Publication date: August 30, 2007
    Applicant: CHISSO CORPORATION
    Inventors: Hirokazu NAGAOKA, Noriyuki OHNISHI, Masaru EGUCHI
  • Patent number: 7047593
    Abstract: A vacuum cleaner includes a main body having an electric blower for generating a suction air flow, a dirt collecting case for centrifugally separating and collecting dirt, and a compression assembly for compressing dirt collected in the dirt collecting case to reduce a volume thereof. The dirt collecting case has a separation chamber for centrifugally separating dirt from the dirt containing air and a dirt collecting chamber in communication with the separation chamber for accumulating the dirt separated by the separation chamber. The compression assembly has a first air intake member provided in the separation chamber and communicating with the electric blower, a second air intake member provided in the dirt collecting chamber and communicating with the electric blower, a shielding plate for selectively opening the first and the second air intake member and an actuator for driving the shielding plate.
    Type: Grant
    Filed: August 8, 2002
    Date of Patent: May 23, 2006
    Assignee: Matsushita Electrical Industrial Co., Ltd.
    Inventors: Hidenori Kitamura, Saburo Kajikawa, Masakazu Onda, Seiji Ishikawa, Yasunori Tsuzaki, Masashi Okushima, Tetsuharu Nomachi, Koji Yamamura, Hirokazu Nagaoka
  • Publication number: 20040128791
    Abstract: A vacuum cleaner includes a first dirt separation unit and a second dirt separation unit. The first dirt separation unit has a first inlet port through which a suction air stream including dirt particles is introduced thereinto, and the second dirt separation unit has a second inlet port through which the air stream introduced into the first dirt separation unit is introduced into the second dirt separation. The first and the second inlet port are disposed such that they are not registered with each other. Accordingly, the dirt particles suctioned are separated in two stages, thereby decreasing the possibility of occlusion of a filter and rapid deterioration of a suction force.
    Type: Application
    Filed: October 23, 2003
    Publication date: July 8, 2004
    Applicant: Matsushita Electric Industrial Co., Ltd.
    Inventors: Yoshiki Kuroki, Seiji Yamaguchi, Tomonori Kato, Masashi Okushima, Yuichi Shimizu, Tomomi Mitani, Hiroshi Mori, Toru Odachi, Yoshiaki Onishi, Hidenori Kitamura, Toshifumi Miyahara, Takaaki Ogawa, Hirokazu Nagaoka
  • Publication number: 20030028994
    Abstract: A vacuum cleaner includes a main body having an electric blower for generating a suction air flow, a dirt collecting case for centrifugally separating and collecting dirt, and a compression assembly for compressing dirt collected in the dirt collecting case to reduce a volume thereof. The dirt collecting case has a separation chamber for centrifugally separating dirt from the dirt containing air and a dirt collecting chamber in communication with the separation chamber for accumulating the dirt separated by the separation chamber. The compression assembly has a first air intake member provided in the separation chamber and communicating with the electric blower, a second air intake member provided in the dirt collecting chamber and communicating with the electric blower, a shielding plate for selectively opening the first and the second air intake member and an actuator for driving the shielding plate.
    Type: Application
    Filed: August 8, 2002
    Publication date: February 13, 2003
    Applicant: Matsushita Electric Industrial Co., Ltd.
    Inventors: Hidenori Kitamura, Saburo Kajikawa, Masakazu Onda, Seiji Ishikawa, Yasunori Tsuzaki, Masashi Okushima, Tetsuharu Nomachi, Koji Yamamura, Hirokazu Nagaoka
  • Patent number: D924307
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: July 6, 2021
    Assignee: SONY CORPORATION
    Inventors: Hirokazu Nagaoka, Takuma Araki