Patents by Inventor Hirokazu Naora

Hirokazu Naora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystals of piperidine derivatives, intermediates for production of the same, and process for producing the same
    Patent number: 6444821
    Abstract: Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidino) ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: September 3, 2002
    Assignee: Ajinomoto Co., Inc.
    Inventors: Akiko Fujii, Mie Kubo, Tomoya Yamamoto, Jiro Shimada, Ryuichi Mihara, Hirokazu Naora, Koji Asai
  • Process for producing piperidinecarboxylic acid amide derivatives
    Patent number: 6355804
    Abstract: A process for producing piperidinecarboylic acid amide derivatives useful as serotonin antagonists, antithrombocytic agents or intermediates for them, which comprises the step of reacting a 2-oxazoline compound with a piperidine derivative in the presence of an acid is provided. This process is an industrially excellent process for producing piperidinecarboylic acid amide derivatives useful as serotonin antagonists, antithrombocytic agents or intermediates for them.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: March 12, 2002
    Assignee: Ajinomoto Co., Inc.
    Inventors: Isao Arai, Takashi Yamamoto, Hirokazu Naora
  • Crystals of piperidine derivatives, intermediates for production of the same, and process for producing the same
    Publication number: 20010056102
    Abstract: Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidino) ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability.
    Type: Application
    Filed: February 6, 2001
    Publication date: December 27, 2001
    Applicant: AJINOMOTO CO., INC.
    Inventors: Akiko Fujii, Mie Kubo, Tomoya Yamamoto, Jiro Shimada, Ryuichi Mihara, Hirokazu Naora, Koji Asai
  • Crystals of piperidine derivatives, intermediates for production of the same, and process for producing the same
    Patent number: 6232323
    Abstract: Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidino) ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: May 15, 2001
    Assignee: Ajinomoto Co., Inc.
    Inventors: Akiko Fujii, Mie Kubo, Tomoya Yamamoto, Jiro Shimada, Ryuichi Mihara, Hirokazu Naora, Koji Asai
  • Process for producing piperidinecarboxylic acid amide derivatives
    Patent number: 6207834
    Abstract: A process for producing piperidinecarboylic acid amide derivatives useful as serotonin antagonists, antithrombocytic agents or intermediates for them, which comprises the step of reacting a 2-oxazoline compound with a piperidine derivative in the presence of an acid is provided. This process is an industrially excellent process for producing piperidinecarboylic acid amide derivatives useful as serotonin antagonists, antithrombocytic agents or intermediates for them.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: March 27, 2001
    Assignee: Ajinomoto Co., Inc.
    Inventors: Isao Arai, Takashi Yamamoto, Hirokazu Naora
  • Crystals of piperidine derivatives, intermediates for production of the same, and process for producing the same
    Patent number: 6184233
    Abstract: Monohydrate and trihydrate crystals of N-(2-(4-(5H dibenzo [a,d]cyclohepten-5-ylidene)-piperidino)ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: February 6, 2001
    Assignee: Ajinomoto Co., Inc.
    Inventors: Akiko Fujii, Mie Kubo, Tomoya Yamamoto, Jiro Shimada, Ryuichi Mihara, Hirokazu Naora, Koji Asai
  • Production of cyclopentenylheptanoic acid derivatives
    Patent number: 4849535
    Abstract: Cyclopentenylheptanoic acid derivatives having the formula: ##STR1## wherein R is hydrogen or C.sub.1 to C.sub.4 alkyl and --(A)-- is: ##STR2## wherein M is hydrogen or triorganosilyl group, are prepared by reacting a compound having the formula: ##STR3## ps wherein X is halogen, with a compound having the formula: The derivatives belong to the pharmacologically-active class of compounds called "prostaglandins".
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: July 18, 1989
    Assignees: Ajinomoto Co., Inc., Mochida Pharmaceutical Co., Ltd.
    Inventors: Hirokazu Naora, Takashi Onuki, Asao Nakamura
  • Method for manufacture of 7-(2,5-dioxocyclopentyl)heptanoic acid derivative
    Patent number: 4658055
    Abstract: A method for the manufacture of a heptanoic acid derivative represented by the formula ##STR1## wherein R.sup.3 stands for an acyloxy group, a halogen atom, or a hydrogen atom, which comprises reacting a cyclooctene derivative represented by the formula ##STR2## wherein Y stands for --R.sup.1, --COR.sup.1 or --SiR.sup.2.sub.3, wherein R.sup.1 is an alkyl group, an aryl group, or an aralkyl group and R.sup.2 is an alkyl group of 1 to 5 carbon atoms, with a compound represented by the formula ##STR3## wherein R.sup.3 has the same meaning as indicated above and X.sup.1 and X.sup.2 each is a halogen atom, is described along with uses for such compounds.
    Type: Grant
    Filed: January 28, 1985
    Date of Patent: April 14, 1987
    Assignee: Ajinomoto Co., Inc.
    Inventors: Takashi Onuki, Hirokazu Naora, Asao Nakamura