Abstract: A cell adsorption material includes fibers or particles of a water-insoluble carrier with at least one bound nitrogen-containing compound. The nitrogen-containing compound is selected from polyamines and aliphatic amines. The fibers or particles have a region A within 1.0 ?m from an outermost surface of a cross-sectional surface of the fibers or the particles, and a region B within 0.5 ?m radius from a center of gravity of the cross-sectional surface of the fibers or the particles, a spectral intensity of 26CN? satisfies formulae (1) and (2) when a spectral intensity of 25C2H? in each of the regions measured by Time of Flight Secondary Ion Mass Spectrometry is set to be 1:0.5?the spectral intensity of 26CN? in the region A?3.0 . . . (1); 3.0? the spectral intensity of 26CN? in the region A/the spectral intensity of 26CN? in the region B?20.0 . . . (2).

Abstract: A nerve regeneration-inducing tube includes a cylindrical body, and a plurality of fibers that are housed in the body and extend in a longitudinal direction of the body. At least a part of the fibers is a modified cross-section fiber that has an axis extending in a longitudinal direction of the fibers, and at least three protrusions that continue in the longitudinal direction of the fibers, protrude from the axis, and have a height of 0.5 ?m or more from the axis.

Abstract: A cell adhesive substrate comprising a substratum, on a surface of which a peptide group is immobilized, wherein the peptide group comprises a peptide containing 40% or more and 75% or less of one or two or more of basic amino acid residues selected from the group consisting of lysine, arginine and histidine and 25% or more of one or two or more of hydrophobic amino acid residues selected from the group consisting of leucine, isoleucine, glycine, alanine, valine, phenylalanine, proline, tryptophan and methionine. There is provided a cell adhesive substrate that is unlikely to cause an immune reaction and can maintain a cell adhesion effect for a long time.

Abstract: A porous adsorption material is used to adsorb and remove an impurity from a solution containing a raw biopharmaceutical compound while suppressing clogging and is high in separation selectivity. The porous adsorption material used to adsorb and remove an impurity from a solution containing a raw biopharmaceutical compound includes a layer containing a nonionic polymer on at least one surface of the porous adsorption material.

Abstract: A filter having a plurality of filter pores penetrating one surface and another surface of the filter, wherein the filter pore has a first opening on the one surface and a second opening on the another surface, a ratio (L1/W1) of a major axis diameter L1 to a minor axis diameter W1 of the first opening is 1.00 or more and 1.20 or less, the minor axis diameter W1 is 7.0 ?m or more and 9.0 ?m or less, a ratio (L2/W2) of a major axis diameter L2 to a minor axis diameter W2 of the second opening is 1.00 or more and 1.20 or less, and a ratio (W2/W1) of the minor axis diameter W2 to the minor axis diameter W1 and a ratio (L2/L1) of the major axis diameter L2 to the major axis diameter L1 are both 1.20 or more and 1.50 or less.

Abstract: A medical diagnostic apparatus includes a receiver circuit that receives three-dimensional volumetric data of a subject’s eye, and a processor configured to separate portions of the three-dimensional volumetric data into separate segments, perform processing differently on each of the separate segments, and combine the separately processed segments to produce an enhanced three-dimensional volumetric data set. The processor is further configured to generate at least one diagnostic metric from the enhanced three-dimensional volumetric data set, and the processor is further configured to evaluate a pathological condition based on the at least one diagnostic metric. Related methods and computer readable media are also disclosed.

Abstract: There is provided a low-cost lighting optical system not requiring the refractive element for each laser chip.

Abstract: A coating agent can be applied to various materials without using radiation, and a medical material using the same. The coating agent containing a copolymer that contains: a monomer unit (unit A) containing a Si—O bond; a vinyl carboxylate monomer unit (unit B); and a monomer unit (unit C) containing a hydrophilic group.

Abstract: An elastic wave device includes a piezoelectric substrate, an IDT electrode on the piezoelectric substrate, and a silicon oxide film arranged on the piezoelectric substrate to cover the IDT electrode. The IDT electrode includes first and second electrode layers laminated on each other, the first electrode layer is made of metal or an alloy with a density higher than a density of metal of the second electrode layer and a density of silicon oxide of the silicon oxide film, the piezoelectric substrate is made of LiNbO3 and ? is in a range of equal to or greater than about 8° and equal to or less than about 32° with Euler Angles (0°±5°, ?, 0°±10°) of the piezoelectric substrate, and the silicon oxide film contains hydrogen atoms, hydroxyl groups, or silanol groups.

Abstract: The present invention aims to provide a porous separation membrane that does not suffer a significant decrease in the protein permeability even after long term use. The porous separation membrane has an asymmetric structure with a dense layer forming one surface layer and with a coarse layer forming the other surface layer, supports a biocompatible polymer, and meet the requirements (1) and (2) given below in surface analysis of a cross section containing the dense layer and the coarse layer performed by TOF-SIMS: (1) the minimum value of normalized intensity of the ion signal attributed to the biocompatible polymer in the coarse layer is 0.15 times or more of the maximum value, and (2) the normalized average intensity of the ion signal attributed to the biocompatible polymer in the dense layer is 2.0 times or more of the normalized average intensity of the ion signal attributed to carboxylic acid in the coarse layer.

Abstract: An object of the present invention is to provide a purification column which is a small purification column in which a volume of a liquid to be treated is reduced in order to reduce the amount of blood to be taken out and which realizes a low pressure loss and has high adsorption performance. The present invention provides a fiber bundle including a plurality of porous fibers that satisfies the following requirements (A) to (E): (A) the porous fiber has a non-hollow shape, (B) an arithmetic average roughness (dry Ra value) of a surface of the porous fiber in a dry state is 11 nm or more and 30 nm or less, (C) an arithmetic average roughness (wet Ra value) of a surface of the porous fiber in a wet state is 12 nm or more and 40 nm or less, (D) a value represented by wet Ra/dry Ra is 1.05 or more, and (E) a linear rate of the fiber bundle represented by (length of fiber bundle)/(length of one porous fiber) is 0.97 or more and 1.00 or less.

Abstract: A fiber structure includes a biodegradable polymer fiber, the fiber structure having two or more peaks in a molecular weight distribution obtained by GPC measurement of the biodegradable polymer, and the fiber structure having one or more peaks in each of a region of 100,000 or less of molecular weight and a region of more than 100,000 of molecular weight in the molecular weight distribution obtained by GPC measurement of the biodegradable polymer.

Abstract: A polymer composition contains polylactic acid and a dilactide/?-caprolactone copolymer, in which a content of the polylactic acid relative to a total of 100 mass % of the polylactic acid and the dilactide/?-caprolactone copolymer is 20 to 40 mass %, and in which the dilactide/?-caprolactone copolymer satisfies (1) an R value represented by a following formula is 0.45 or more and 0.99 or less: R = [ AB ] ? / ? ( 2 ? [ A ] ? [ B ] ) × 100 where [A] is a molar fraction (%) of a dilactide residue in the dilactide/?-caprolactone copolymer, [B] is a molar fraction (%) of an ?-caprolactone residue in the dilactide/?-caprolactone copolymer, and [AB] is a molar fraction (%) of a structure in which a dilactide residue and an ?-caprolactone residue are adjacent to each other (A-B and B-A) in the dilactide/?-caprolactone copolymer, and (2) at least one of the dilactide residue and the ?-caprolactone residue has a degree of crystallization of less than 14%.

Abstract: A nerve regeneration-inducing tube includes a cylindrical body, and a plurality of fibers that are housed in the body and extend in a longitudinal direction of the body. At least a part of the fibers is a modified cross-section fiber that has an axis extending in a longitudinal direction of the fibers, and at least three protrusions that continue in the longitudinal direction of the fibers, protrude from the axis, and have a height of 0.5 ?m or more from the axis.

Abstract: A separation membrane module includes a case and a separation membrane built in the case, wherein the separation membrane module satisfies the following requirements (1) to (3): (1) the separation membrane contains a hydrophobic polymer, a hydrophilic polymer, and a biocompatible copolymer, the hydrophilic polymer containing a hydrophilic polymer having mobility, (2) the separation membrane contains the hydrophilic polymer having mobility in a range of 1.0 to 1.7% by mass, and (3) a water content per self-weight of the separation membrane is in a range of 0 to 10% by mass. The separation membrane module is provided in which fouling of a membrane is suppressed and the amount of eluted substance is small.

Abstract: The present invention provides a medical molded article including a bioabsorbable polyester and having excellent followability to a living body, and the present invention is a medical molded article including a bioabsorbable polyester, the medical molded article having an amount-of-work-holding rate of 55% or more, the amount-of-work-holding rate defined as a rate of an amount of work generated finally by an operation that is repeated 10 times to an amount of work generated first by the operation, the operation in which a tensile stress is applied to the medical molded article in a direction of a maximum length of the medical molded article to generate a tensile strain of 100% with respect to an initial length.

Abstract: The present invention provides a hollow fiber membrane module which makes it possible to concentrate incubated platelets by efficiently removing water from an incubated platelet suspension liquid containing incubated platelets while suppressing deterioration of the function of the incubated platelets. The present invention provides an incubated platelet concentration module in which a plurality of hollow fiber membranes each having pores with an average pore diameter of 2 ?m or less on a surface of the hollow fiber membrane are packed in a casing having at least one inlet for supplying an incubated platelet suspension liquid before concentration into the hollow fiber membranes, wherein a value (X/Y1) obtained by dividing a total cross-sectional area (X) of the plurality of hollow fiber membranes by a total cross-sectional area (Y1) of the least one inlet is 4.0 or less.

Abstract: A polyester copolymer has two types of ester bond-forming monomer residues as main structural units when the two types of ester bond-forming monomers are defined as “monomer A” and “monomer B”, respectively, the polyester copolymer satisfies (1) and (2): (1) an R value represented by equation: R value=[AB]/(2[A][B])×100 [A]: mole fraction of monomer A residues in the polyester copolymer [% by mol], [B]: mole fraction of monomer B residues in the polyester copolymer [% by mol], and [AB]: mole fraction of a structure in which the monomer A residues and the monomer B residues are adjacent to each other (A-B and B-A) in the polyester copolymer [% by mol], is 0.45 or more and 0.99 or less; and (2) a crystallization rate of at least one of the monomer A residues and the monomer B residues is less than 14%.

Abstract: A cell adhesive substrate comprising a substratum, on a surface of which a peptide group is immobilized, wherein the peptide group comprises a peptide containing 40% or more and 75% or less of one or two or more of basic amino acid residues selected from the group consisting of lysine, arginine and histidine and 25% or more of one or two or more of hydrophobic amino acid residues selected from the group consisting of leucine, isoleucine, glycine, alanine, valine, phenylalanine, proline, tryptophan and methionine. There is provided a cell adhesive substrate that is unlikely to cause an immune reaction and can maintain a cell adhesion effect for a long time.

Abstract: A polyester copolymer has two types of ester bond-forming monomer residues as main structural units when the two types of ester bond-forming monomers are defined as “monomer A” and “monomer B”, respectively, the polyester copolymer satisfies (1) and (2): (1) an R value represented by equation: R value=[AB]/(2[A][B])×100 [A]: mole fraction of monomer A residues in the polyester copolymer [% by mol], [B]: mole fraction of monomer B residues in the polyester copolymer [% by mol], and [AB]: mole fraction of a structure in which the monomer A residues and the monomer B residues are adjacent to each other (A-B and B-A) in the polyester copolymer [% by mol], is 0.45 or more and 0.99 or less; and (2) a crystallization rate of at least one of the monomer A residues and the monomer B residues is less than 14%.