Patents by Inventor HIROKI ASAKURA

HIROKI ASAKURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION
    Publication number: 20230348495
    Abstract: The present invention relates to a compound having inhibitory activity against KRAS G12D mutation or a salt thereof, and relates to a pharmaceutical composition comprising the compound as an active ingredient.
    Type: Application
    Filed: November 27, 2020
    Publication date: November 2, 2023
    Inventors: YUICHI KAWAI, KAZUAKI SHIBATA, HIROKI ASAKURA, TAKAO UNO, TAKESHI SAGARA, MASAYUKI NAKAMURA, YU KOBAYAKAWA, RHIAN SARA HOLVEY
  • 4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF
    Publication number: 20230023023
    Abstract: The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.
    Type: Application
    Filed: October 29, 2020
    Publication date: January 26, 2023
    Inventors: KAZUAKI SHIBATA, YUICHI KAWAI, HIROKI ASAKURA, TETSUYA SUGIMOTO, NAOKI EGASHIRA, TOMOHIRO YAMAMOTO, TATSUYA SUZUKI, YUKI KATAOKA, TAKESHI SAGARA, TOSHIHIRO SAKAMOTO, HITOMI KONDO, CHRISTOPHER CHARLES FREDERICK HAMLETT, PATRICK SCHÖPF, DAVID GEOFFREY TWIGG