Patents by Inventor Hiroki Hayase

Hiroki Hayase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10292976
    Abstract: The present invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: May 21, 2019
    Assignee: RIKEN
    Inventors: Akira Wada, Hiroki Hayase, Nobumoto Watanabe, Hiroyuki Osada, Takeshi Shimizu, Konstanty Wierzba
  • Publication number: 20190054074
    Abstract: The present invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Application
    Filed: October 23, 2018
    Publication date: February 21, 2019
    Applicant: RIKEN
    Inventors: Akira WADA, Hiroki HAYASE, Nobumoto WATANABE, Hiroyuki OSADA, Takeshi SHIMIZU, Konstanty WIERZBA
  • Patent number: 10137119
    Abstract: The invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: November 27, 2018
    Assignee: RIKEN
    Inventors: Akira Wada, Hiroki Hayase, Nobumoto Watanabe, Hiroyuki Osada, Takeshi Shimizu, Konstanty Wierzba
  • Publication number: 20180104226
    Abstract: The invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Application
    Filed: December 19, 2017
    Publication date: April 19, 2018
    Applicant: RIKEN
    Inventors: Akira WADA, Hiroki HAYASE, Nobumoto WATANABE, Hiroyuki OSADA, Takeshi SHIMIZU, Konstanty WIERZBA
  • Patent number: 9861626
    Abstract: The present invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: January 9, 2018
    Assignee: RIKEN
    Inventors: Akira Wada, Hiroki Hayase, Nobumoto Watanabe, Hiroyuki Osada, Takeshi Shimizu, Konstanty Wierzba
  • Publication number: 20170143722
    Abstract: The main purpose of the invention is to provide a novel aromatic heterocyclic derivative or a pharmaceutically acceptable salt thereof. Examples of the invention include aromatic heterocyclic derivatives represented by general formula [1] and pharmaceutically acceptable salts thereof. In formula [1]: R1 represents phenyl optionally substituted with one or two groups selected from the group consisting of halogens, as well as alkyls and alkoxys optionally substituted by halogens; R2 represents hydrogen, an alkyl, cycloalkyl, or alkoxy optionally substituted by a halogen, or a heteroaryl optionally substituted by an alkyl; X represents CR3, and Y represents N or CR4, or X represents N, and Y represents CR4; and Z represents CR5 or N.
    Type: Application
    Filed: January 10, 2017
    Publication date: May 25, 2017
    Applicant: NIPPON SHINYAKU CO., LTD.
    Inventors: Katsutoshi HORI, Hiroki HAYASE, Tomohiro TERADA
  • Patent number: 9580413
    Abstract: The main purpose of the invention is to provide a novel aromatic heterocyclic derivative or a pharmaceutically acceptable salt thereof. Examples of the invention include aromatic heterocyclic derivatives represented by general formula [1] and pharmaceutically acceptable salts thereof. In formula [1]: R1 represents phenyl optionally substituted with one or two groups selected from the group consisting of halogens, as well as alkyls and alkoxys optionally substituted by halogens; R2 represents hydrogen, an alkyl, cycloalkyl, or alkoxy optionally substituted by a halogen, or a heteroaryl optionally substituted by an alkyl; X represents CR3, and Y represents N or CR4, or X represents N, and Y represents CR4; and Z represents CR5 or N.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: February 28, 2017
    Assignee: NIPPON SHINYAKU CO., LTD.
    Inventors: Katsutoshi Hori, Hiroki Hayase, Tomohiro Terada
  • Publication number: 20160324847
    Abstract: The present invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the following formula (I), (III), (IV), (V), (VI), or (VII), such as tris(2-pyridylmethyl)amine.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 10, 2016
    Inventors: Akira WADA, Hiroki HAYASE, Nobumoto WATANABE, Hiroyuki OSADA, Takeshi SHIMIZU, Konstanty WIERZBA
  • Publication number: 20150152095
    Abstract: The main purpose of the invention is to provide a novel aromatic heterocyclic derivative or a pharmaceutically acceptable salt thereof. Examples of the invention include aromatic heterocyclic derivatives represented by general formula [1] and pharmaceutically acceptable salts thereof. In formula [1]: R1 represents phenyl optionally substituted with one or two groups selected from the group consisting of halogens, as well as alkyls and alkoxys optionally substituted by halogens; R2 represents hydrogen, an alkyl, cycloalkyl, or alkoxy optionally substituted by a halogen, or a heteroaryl optionally substituted by an alkyl; X represents CR3, and Y represents N or CR4, or X represents N, and Y represents CR4; and Z represents CR5 or N.
    Type: Application
    Filed: May 29, 2013
    Publication date: June 4, 2015
    Applicant: NIPPON SHINYAKU CO., LTD.
    Inventors: Katsutoshi Hori, Hiroki Hayase, Tomohiro Terada