Patents by Inventor Hiroki Kawaguchi

Hiroki Kawaguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240182483
    Abstract: [Problem] To provide a compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer. [Means for resolution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a quinazoline compound has an excellent degradation-inducing action on a G12D mutant KRAS protein and a G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The quinazoline compound or a salt thereof of the present invention can be used as a therapeutic agent for pancreatic cancer.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 6, 2024
    Inventors: Tomohiro YOSHINARI, Hiroki ISHIOKA, Eiji KAWAMINAMI, Hideyuki WATANABE, Kenichi KAWAGUCHI, Kazuyuki KURAMOTO, Tomoyoshi IMAIZUMI, Takahiro MORIKAWA, Hisao HAMAGUCHI, Sunao IMADA, Mitsuaki OKUMURA, Takeyuki NAGASHIMA, Kohei INAMURA
  • Publication number: 20240170202
    Abstract: To improve a coil component having a structure in which a coil part is embedded in a magnetic member. A coil component includes a coil part embedded in the magnetic members and terminal electrodes each made of a conductive paste. Conductor layers constituting the coil part respectively have coil conductor patterns and electrode patterns exposed from a mounting surface. The terminal electrode has an area provided at a position covering the electrode patterns on the mounting surface and areas provided at positions not covering the electrode patterns on the mounting surface. A part of the area constitutes a protruding part protruding in the x-direction. The terminal electrode thus has the protruding part, thereby making misalignment of mounting position in the z-direction less likely to occur at the time of mounting.
    Type: Application
    Filed: February 22, 2022
    Publication date: May 23, 2024
    Inventors: Yuuichi KAWAGUCHI, Naoaki FUJII, Masanori SUZUKI, Takuya TAKEUCHI, Tomonaga NISHIKAWA, Hiroki SHIBA
  • Publication number: 20240150366
    Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 9, 2024
    Inventors: Kenichi KAWAGUCHI, Kazuyuki KURAMOTO, Tomoyoshi IMAIZUMI, Takahiro MORIKAWA, Mitsuaki OKUMURA, Sunao IMADA, Eiji KAWAMINAMI, Ryo SATO, Yohei SEKI, Hisao HAMAGUCHI, Hiroki ISHIOKA, Hiroki FUKUDOME, Ikumi KURIWAKI, Takeyuki NAGASHIMA
  • Patent number: 11066564
    Abstract: The present invention relates to a water-based pigment dispersion containing a polymer dispersant and a pigment, the polymer dispersant being prepared by crosslinking a carboxy group-containing water-insoluble polymer (A) with a water-insoluble polyfunctional epoxy compound, in which carboxy groups of the water-insoluble polymer (A) are at least partially neutralized by an alkali metal compound, and the water-based pigment dispersion satisfies the following conditions 1 to 3. The water-based pigment dispersion of the present invention can exhibit excellent redispersibility capable of suppressing solidification of the pigment or the polymer in ink ejection nozzles and can ensure good storage stability under high-temperature conditions.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: July 20, 2021
    Assignee: KAO CORPORATION
    Inventors: Yusuke Shimizu, Koji Azuma, Hirokazu Hyakuda, Tetsuya Eguchi, Hiroki Kawaguchi
  • Publication number: 20210062030
    Abstract: The present invention relates to [1] a water-based pigment dispersion formed by dispersing a pigment in a water-based medium with a polymer dispersant, in which the dispersant contains an acid group-containing (meth)acrylic resin (A) and a polyurethane resin (B); the resin (A) is crosslinked with a crosslinking agent (C), and a crosslinking degree of the resin (A) is from 0.12 to 0.65; and a mass ratio of the pigment [pigment/whole solid components of water-based pigment dispersion] is from 0.25 to 0.75, and [2] a process for producing a water-based pigment dispersion, including step 1 of subjecting a pigment mixture containing a pigment, an acid group-containing (meth)acrylic resin (A) and a polyurethane resin (B) to dispersion treatment to obtain a dispersion; and step 2 of subjecting the dispersion obtained in the step 1 to crosslinking treatment with a crosslinking agent (C).
    Type: Application
    Filed: December 28, 2018
    Publication date: March 4, 2021
    Applicant: KAO CORPORATION
    Inventor: Hiroki KAWAGUCHI
  • Publication number: 20200332135
    Abstract: The present invention relates to [1] a water-based pigment dispersion formed by dispersing a pigment in a water-based medium with a polymer dispersant, in which the polymer dispersant contains a (meth)acrylic resin (A) and a resin (B); and the resin (B) is at least one resin selected from the group consisting of a polyester resin (B1), an acid-modified polyolefin resin (B2) and a vinyl chloride-based resin (B3), and [2] a process for producing a water-based pigment dispersion, including the following steps 1 and 2: Step 1: subjecting a pigment mixture containing a pigment, an acid group-containing (meth)acrylic resin (A), and a resin (B) which is at least one resin selected from the group consisting of a polyester resin (B1), an acid-modified polyolefin resin (B2) and a vinyl chloride-based resin (B3) to dispersion treatment to obtain a dispersion; and Step 2: subjecting the dispersion obtained in the step 1 to crosslinking treatment with a crosslinking agent (C).
    Type: Application
    Filed: December 28, 2018
    Publication date: October 22, 2020
    Applicant: KAO CORPORATION
    Inventor: Hiroki KAWAGUCHI
  • Patent number: 10738207
    Abstract: The present invention relates to a water-based pigment dispersion having not only excellent storage stability capable of suppressing solidification of a pigment or the like in ink ejection nozzles, but also excellent ejection properties and fixing properties, while maintaining good water resistance of the pigment dispersion as an advantage attained by using the pigment therein.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: August 11, 2020
    Assignee: KAO CORPORATION
    Inventors: Koji Azuma, Hirokazu Hyakuda, Yusuke Shimizu, Tetsuya Eguchi, Hiroki Kawaguchi
  • Publication number: 20190315983
    Abstract: The present invention relates to a water-based pigment dispersion containing a polymer dispersant and a pigment, the polymer dispersant being prepared by crosslinking a carboxy group-containing water-insoluble polymer (A) with a water-insoluble polyfunctional epoxy compound, in which carboxy groups of the water-insoluble polymer (A) are at least partially neutralized by an alkali metal compound, and the water-based pigment dispersion satisfies the following conditions 1 to 3. The water-based pigment dispersion of the present invention can exhibit excellent redispersibility capable of suppressing solidification of the pigment or the polymer in ink ejection nozzles and can ensure good storage stability under high-temperature conditions.
    Type: Application
    Filed: October 13, 2017
    Publication date: October 17, 2019
    Applicant: KAO CORPORATION
    Inventors: Yusuke SHIMIZU, Koji AZUMA, Hirokazu HYAKUDA, Tetsuya EGUCHI, Hiroki KAWAGUCHI
  • Publication number: 20190284410
    Abstract: The present invention relates to a water-based pigment dispersion having not only excellent storage stability capable of suppressing solidification of a pigment or the like in ink ejection nozzles, but also excellent ejection properties and fixing properties, while maintaining good water resistance of the pigment dispersion as an advantage attained by using the pigment therein.
    Type: Application
    Filed: December 8, 2016
    Publication date: September 19, 2019
    Applicant: KAO CORPORATION
    Inventors: Koji AZUMA, Hirokazu HYAKUDA, Yusuke SHIMIZU, Tetsuya EGUCHI, Hiroki KAWAGUCHI
  • Publication number: 20070235746
    Abstract: In a light emitting diode package or a light emitting diode, a cover body having an opening with a reflecting surface is attached on an upper portion of a base body on which a light emitting diode element is mounted. The base body is formed of alumina ceramics having a pore diameter of 0.10 to 1.25 ?m or a porosity of 10% or more, and a thermal via is formed in the base body. Accordingly, it is possible to improve luminance and heat radiating characteristics of the light emitting diode package and the light emitting diode which uses alumina ceramics.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 11, 2007
    Inventors: Kazuma Mitsuyama, Itsuki Yamamoto, Kouji Kudo, Nario Fukumoto, Hiroyuki Fukae, Kengo Nishiyama, Takumi Narita, Hiroki Kawaguchi