Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: A suction method is provided as a method of performing, by using a suction collet, suction of a Fabry-Perot interference filter including a substrate and a laminated structure that is provided on the substrate and that includes a main surface facing the side opposite to the substrate, the method including a first step of arranging the suction collet so as to face the main surface, a second step of bringing the suction collet into contact with the Fabry-Perot interference filter after the first step, and a third step of suctioning the Fabry-Perot interference filter by using the suction collet after the second step.

Abstract: A polyisocyanurate raw material composition containing a polyfunctional isocyanate, a compound (I) represented by general formula (I) shown below, and an epoxy compound. In general formula (I), each of R1 to R5 represents a hydrogen atom, an alkoxy group of 1 to 10 carbon atoms, an alkyl group of 2 to 10 carbon atoms (or an alkyl group of 1 to 10 carbon atoms in the case of R3 to R5), an aryl group of 6 to 12 carbon atoms, an amino group, a monoalkylamino group of 1 to 10 carbon atoms, a dialkylamino group of 2 to 20 carbon atoms, a carboxy group, a cyano group, a fluoroalkyl group of 1 to 10 carbon atoms, or a halogen atom (provide that R1 and R2 are not both hydrogen atoms).

Abstract: A material design apparatus is provided that can derive an optimal solution of a design condition of a polymer that satisfies desired and required physical properties.

Abstract: A polyisocyanurate raw material composition containing a polyfunctional isocyanate, a compound (I) represented by general formula (I) shown below, and an epoxy compound. In general formula (I), each of R1 to R5 represents a hydrogen atom, an alkoxy group of 1 to 10 carbon atoms, an alkyl group of 2 to 10 carbon atoms (or an alkyl group of 1 to 10 carbon atoms in the case of R3 to R5), an aryl group of 6 to 12 carbon atoms, an amino group, a monoalkylamino group of 1 to 10 carbon atoms, a dialkylamino group of 2 to 20 carbon atoms, a carboxy group, a cyano group, a fluoroalkyl group of 1 to 10 carbon atoms, or a halogen atom (provide that R1 and R2 are not both hydrogen atoms).

Abstract: There is provided a polarizing plate excellent in durability. A method of producing a polarizing plate according to an embodiment of the present invention includes: preparing a polarizing film laminate including a polarizer and a protective film arranged on at least one side of the polarizer; and shrinking the polarizing film laminate.

Abstract: A polarizing plate excellent in durability. A polarizing plate 100 according to one embodiment includes a polarizer 10; and a pair of protective films 21, 22 respectively arranged on both main surfaces of the polarizer 10, wherein the polarizing plate 100 has a polarizer void portion 30 formed by positioning of an end surface 10a of the polarizer 10 inward in a plane direction relative to each of end surfaces 21a, 22a of the protective films 21, 22.

Abstract: There is provided a polarizing plate excellent in durability. A polarizing plate 100 according to one embodiment of the present invention includes a polarizer 10; and a pair of protective films 21, 22 respectively arranged on both main surfaces of the polarizer 10, wherein the polarizing plate 100 has a polarizer void portion 30 formed by positioning of an end surface 10a of the polarizer 10 inward in a plane direction relative to each of end surfaces 21a, 22a of the protective films 21, 22.

Abstract: There is provided a polarizing plate excellent in durability. A method of producing a polarizing plate according to an embodiment of the present invention includes: preparing a polarizing film laminate including a polarizer and a protective film arranged on at least one side of the polarizer; and shrinking the polarizing film laminate.

Abstract: There is provided a polarizer excellent in heat resistance. A polarizer according to an embodiment of the present invention includes a resin film containing iodine, wherein an end portion of the resin film has formed therein a high-concentration portion having a concentration of a substance that forms a counter ion of iodine higher than that of another portion.

Abstract: There is provided a polarizing plate excellent in durability. A method of producing a polarizing plate according to an embodiment of the present invention includes: preparing a polarizing film laminate including a polarizer and a protective film arranged on at least one side of the polarizer; and shrinking the polarizing film laminate.

Abstract: There is provided a polarizing plate excellent in durability. A method of producing a polarizing plate according to an embodiment of the present invention includes: preparing a polarizing film laminate including a polarizer and a protective film arranged on at least one side of the polarizer; and shrinking the polarizing film laminate.

Abstract: Provided is an image display mirror that includes a half mirror and an image display apparatus, reduces an influence of a reflected image provided by the half mirror, and is excellent in visibility of an image displayed on the image display apparatus. The image display mirror for a vehicle includes a first polarizing plate, a half mirror, and an image display apparatus in the stated order from a viewer side. In one embodiment, the first polarizing plate includes a polarizer, and the direction of the polarizer of the first polarizing plate is set so that the transmittance of light output from the image display apparatus that is transmitted through the first polarizing plate becomes maximum.

Abstract: There is provided a polarizer excellent in heat resistance. A polarizer according to an embodiment of the present invention includes a resin film containing iodine, wherein an end portion of the resin film has formed therein a high-concentration portion having a concentration of a substance that forms a counter ion of iodine higher than that of another portion.

Abstract: There is provided a polarizer excellent in heat resistance. A polarizer according to an embodiment of the present invention includes a resin film containing iodine, wherein an end portion of the resin film has formed therein a high-concentration portion having a concentration of a substance that forms a counter ion of iodine higher than that of another portion.

Abstract: A vehicle includes: an image display mirror including a first polarizing plate, a half mirror, and an image display apparatus in the stated order from a viewer side; and a second polarizing plate, in which: the image display mirror is arranged so as to b viewable by a driver of the vehicle; the half mirror is configured to be oriented in different directions between when an image is displayed on the image display apparatus and when the image is not displayed thereon; the second polarizing plate is arranged so that light transmitted through the second polarizing plate reaches a first polarizing plate side of the image display mirror when the image is displayed on the image display apparatus; and the vehicle is configured so that the transmitted light of the second polarizing plate reaching the image display mirror is prevented from being transmitted through the first polarizing plate.

Abstract: There is provided a polarizer excellent in durability. A polarizer according to one embodiment of the present invention includes a resin film containing boric acid, wherein the resin film has a low-concentration portion, which contains a lower concentration of the boric acid than that in any other site, formed in an end portion thereof.

Abstract: Provided is an image display mirror that includes a half mirror and an image display apparatus, reduces an influence of a reflected image provided by the half mirror, and is excellent in visibility of an image displayed on the image display apparatus. The image display mirror for a vehicle includes: a circularly polarizing plate arranged attachably and removably; a half mirror; and an image display apparatus in the stated order from a viewer side. In one embodiment, attached and removed states of the circularly polarizing plate are switched when an image is displayed on the image display apparatus and when the image is not displayed thereon, and when the image is displayed, the circularly polarizing plate is arranged between the half mirror and a viewer.

Abstract: There is provided a polarizing plate excellent in durability. A polarizing plate 100 according to one embodiment of the present invention includes a polarizer 10; and a pair of protective films 21, 22 respectively arranged on both main surfaces of the polarizer 10, wherein the polarizing plate 100 has a polarizer void portion 30 formed by positioning of an end surface 10a of the polarizer 10 inward in a plane direction relative to each of end surfaces 21a, 22a of the protective films 21, 22.

Abstract: Provided is a hard coat film, including: a transparent film; and a hard coat layer formed on the transparent film, in which: the surface free energy of the hard coat layer is equal to or more than a certain value; the hard coat film has a mixed region in which a component of the transparent film and a component of the hard coat layer are mixed; the refractive index of the mixed region continuously changes toward the thickness direction of the hard coat film; and a refractive index change gradient falls within a certain range.