Patents by Inventor Hiroki Sakamoto

Hiroki Sakamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8377604
    Abstract: A fuel cell stack structure is basically provided with a stack entity and at least one tie rod. The stack entity includes a plurality of solid electrolyte fuel cell units stacked together in a stacking direction. The tie rod extends through the stack entity to fasten the solid electrolyte fuel cell units so that the solid electrolyte fuel cell units are pressed against each other in the stacking direction. The tie rod has an outer cylinder, an inner shaft fitting into the outer cylinder, and a joining material disposed between the outer cylinder and the inner shaft. The joining material fastens the outer cylinder and the inner shaft together in an axial direction of the tie rod and is configured and arranged to maintain a cured state at an operating temperature.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: February 19, 2013
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Yasushi Nakajima, Tatsuya Yaguchi, Hiroki Sakamoto, Yu Owada, Hiroshi Sakurai, Yoshiteru Yasuda
  • Patent number: 8372647
    Abstract: The present invention provides novel markers for diagnosing pancreatic cancer, and methods for determining if a subject has pancreatic cancer utilizing the markers, etc. The methods involve comparing mass-spectrometric peaks of certain sugar chains, obtained from patients' blood and determining if there is a significant decrease in peak intensity, compared with corresponding peaks from patients without pancreatic cancer.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: February 12, 2013
    Assignee: Sumitomo Bakelite Company Limited
    Inventors: Tokuzo Arao, Kazuko Matsumoto, Kazuto Nishio, Hiroki Sakamoto, Masayuki Kitano, Masatoshi Kudo
  • Publication number: 20120326827
    Abstract: In a built-in-coil substrate, when viewed in perspective in a stacking direction in which insulating layers of a substrate body are stacked, mutually superposed second coil elements are located further inward than inner peripheries of mutually superposed first coil elements. A cavity is continuous between at least one of the second coil elements and one insulating layer that is in contact with the second coil element(s), and another insulating layer that opposes the second coil element(s) such that the second coil element(s) are exposed, and, when viewed in perspective in the stacking direction, the cavities have annular shapes and extend further inward than the outer peripheries of the mutually superposed first coil elements, there being an interval provided between the cavities and these outer peripheries, and further outward than the inner peripheries of the mutually superposed second coil elements.
    Type: Application
    Filed: September 4, 2012
    Publication date: December 27, 2012
    Applicant: MURATA MANUFACTURING CO., LTD.
    Inventors: Jyunichi NANJYO, Hiroki SAKAMOTO
  • Publication number: 20120282538
    Abstract: A fuel cell stack structure is basically provided with a stack entity and at least one tie rod. The stack entity includes a plurality of solid electrolyte fuel cell units stacked together in a stacking direction. The tie rod extends through the stack entity to fasten the solid electrolyte fuel cell units so that the solid electrolyte fuel cell units are pressed against each other in the stacking direction. The tie rod has an outer cylinder, an inner shaft fitting into the outer cylinder, and a joining material disposed between the outer cylinder and the inner shaft. The joining material fastens the outer cylinder and the inner shaft together in an axial direction of the tie rod and is configured and arranged to maintain a cured state at an operating temperature.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 8, 2012
    Applicant: NISSAN MOTOR CO., LTD.
    Inventors: Yasushi NAKAJIMA, Tatsuya YAGUCHI, Hiroki SAKAMOTO, Yu OWADA, Hiroshi SAKURAI, Yoshiteru YASUDA
  • Patent number: 8241561
    Abstract: Inventors of the present invention have found that, by manufacturing a stress-buffering material with a Ca-containing aluminum alloy including 0.1 to 12 at % of Ca, the stress-buffering material at low cost, capable of expanding its use in various fields, and having low Young's modulus that is beyond a conventional level, can be obtain.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: August 14, 2012
    Assignees: Nissan Motor Co., Ltd., National University Corporation Kitami Institute of Technology
    Inventors: Fumihiko Gejima, Hiroki Sakamoto, Mamoru Sayashi
  • Patent number: 8163863
    Abstract: A polysilane having excellent functionalities (e.g., solubility in a solvent and reactivity) is obtained by introducing a structural unit of the following formula (1) to a polysilane through a reaction of a dihalosilane having a Si—H bond and adding a hydrosilylatable compound (e.g., a compound having a carbon-carbon unsaturated bond) to the Si—H bond, wherein R1 represents a hydrogen atom, an organic group, or a silyl group; and “n” denotes an integer of not less than 1.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: April 24, 2012
    Assignee: Osaka Gas Co., Ltd.
    Inventors: Hiroki Sakamoto, Hiroaki Murase, Tsuyoshi Fujiki, Shingo Osawa, Yoshiyuki Morita, Tetsuya Hosomi, Nobuaki Aoki
  • Patent number: 8125088
    Abstract: Embodiments of the invention provide a semiconductor device having high reliability as they ease the thermal stress or a heat distortion or strain occurring during the manufacturing process or during operation, and the embodiments function with stability for a long time. A semiconductor device has a semiconductor substrate, an insulating ceramic plate on which the semiconductor substrate is mounted and stress buffer 40 that eases a thermal stress. The stress buffer is provided between the semiconductor substrate and the insulating ceramic plate and can be provided on a surface of the insulating ceramic plate that is opposite to a surface on which the semiconductor substrate is mounted. The stress buffer is formed from a structure including at least Al and a second phase. The second phase is Al4X where X is at least one element of alkaline earth metal elements.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: February 28, 2012
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Fumihiko Gejima, Hiroki Sakamoto
  • Publication number: 20110309512
    Abstract: Embodiments of the invention provide a semiconductor device having high reliability as they ease the thermal stress or a heat distortion or strain occurring during the manufacturing process or during operation, and the embodiments function with stability for a long time. A semiconductor device has a semiconductor substrate, an insulating ceramic plate on which the semiconductor substrate is mounted and stress buffer 40 that eases a thermal stress. The stress buffer is provided between the semiconductor substrate and the insulating ceramic plate and can be provided on a surface of the insulating ceramic plate that is opposite to a surface on which the semiconductor substrate is mounted. The stress buffer is formed from a structure including at least Al and a second phase. The second phase is Al4X where X is at least one element of alkaline earth metal elements.
    Type: Application
    Filed: September 8, 2008
    Publication date: December 22, 2011
    Applicant: NISSAN MOTOR CO., LTD.
    Inventors: Fumihiko Gejima, Hiroki Sakamoto
  • Patent number: 7998968
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. For example, the compound may be substituted pyrimidines and pharmaceutical compositions of the formula (I) where X=—CR3; X1=—CR2 or —NR2; and X2=—CR5 or —NR5. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: August 16, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa, Koji Fuji
  • Publication number: 20110112120
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
    Type: Application
    Filed: November 25, 2009
    Publication date: May 12, 2011
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa, Koji Fuji
  • Publication number: 20110083737
    Abstract: With a view to realizing a titanium oxide composite that has a large surface area and that enables efficient transfer of electrons by covering a surface of rod-like or fibrous carbon with a covering layer comprising titanium oxide particles connected to one another, an object of the invention is to develop a material useful as an active material for dye-sensitized solar cells, and a process for producing the material; a porous titanium oxide-covered carbon material composition, and a process for producing the composition; and a photoelectric conversion element comprising the titanium oxide-covered carbon material or porous titanium oxide-covered carbon material composition.
    Type: Application
    Filed: June 19, 2009
    Publication date: April 14, 2011
    Applicant: OSAKA GAS CO., LTD.
    Inventors: Hitoshi Nishino, Ryoichi Nishida, Hiroaki Matsuyoshi, Hiroki Sakamoto, Haruo Tomita, Hidekazu Hayama, Minoru Tabuchi, Nobuko Ichimura, Tomoe Deguchi
  • Publication number: 20110079276
    Abstract: With a view to realizing a titanium oxide structure that has a large surface area and enables efficient transfer of ions and electrons by virtue of titanium oxide particles connected to one another, an object of the invention is to develop a material useful as an active material for dye-sensitized solar cells, and a process for producing the material; a porous titanium oxide composition and a process for producing the composition; and a photoelectric conversion element comprising the titanium oxide structure or porous titanium oxide composition.
    Type: Application
    Filed: June 19, 2009
    Publication date: April 7, 2011
    Applicant: OSAKA GAS CO., LTD.
    Inventors: Hitoshi Nishino, Ryoichi Nishida, Hiroaki Matsuyoshi, Hiroki Sakamoto, Haruo Tomita, Hidekazu Hayama, Minoru Tabuchi, Nobuko Ichimura, Tomoe Deguchi
  • Publication number: 20110065141
    Abstract: The present invention is to provide a novel marker for diagnosing pancreatic cancer, a method for determining if a subject has pancreatic cancer utilizing the marker, etc. The present inventors collected blood from patients of 78 cases in total including patients of 24 cases with pancreaticobiliary-duct benign disorder (16 gallstone cases and 8 pancreatitis cases) and patients of 54 cases with pancreatic cancer, and mass spectrometry was performed on N-linked sugar chains in plasma. From the 74 mass-spectrometric peaks detected, 65 sugar chains were extracted based on the results of PAM analysis. These extracted sugar chains were then used to predict pancreatic cancer or pancreaticobiliary-duct benign disorder, to correctly diagnose 74% cases.
    Type: Application
    Filed: May 8, 2009
    Publication date: March 17, 2011
    Applicant: SUMITOMO BAKELITE COMPANY LIMITED
    Inventors: Tokuzo Arao, Kazuko Matsumoto, Kazuto Nishio, Hiroki Sakamoto, Masayuki Kitano, Masatoshi Kudo
  • Patent number: 7875637
    Abstract: The present invention relates to a compound represented by the formula (I) wherein R1 is a group represented by the formula wherein R2, R3, R4, R5, R6, R7 and R8 are each independently a hydrogen atom or a C1-6 alkyl, or a salt thereof. The compound of the present invention is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and metabolic diseases such as diabetes and the like.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: January 25, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Mami Ojima
  • Patent number: 7803940
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
    Type: Grant
    Filed: May 2, 2008
    Date of Patent: September 28, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa, Koji Fuji
  • Publication number: 20100172792
    Abstract: Inventors of the present invention have found that, by manufacturing a stress-buffering material with a Ca-containing aluminum alloy including 0.1 to 12 at % of Ca, the stress-buffering material at low cost, capable of expanding its use in various fields, and having low Young's modulus that is beyond a conventional level, can be obtain.
    Type: Application
    Filed: September 11, 2008
    Publication date: July 8, 2010
    Applicant: NISSAN MOTOR CO., LTD
    Inventors: Fumihiko Gejima, Hiroki Sakamoto, Mamoru Sayashi
  • Publication number: 20100137281
    Abstract: The present invention aims to provide a compound having superior pharmacological action, physicochemical properties and the like, which is useful for the prophylaxis or treatment s of circulatory diseases such as hypertension, cardiac diseases, arteriosclerosis, renal diseases, cerebral apoplexy and the like and/or metabolic diseases such as hyperlipidemia, obesity, diabetes and the like, central nervous disorders such as cerebral infarction and the like, mental diseases such as dementia, depression and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
    Type: Application
    Filed: May 20, 2008
    Publication date: June 3, 2010
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Takanobu Kuroita, Hideyuki Igawa, Hiroki Sakamoto, Kouhei Asano, Minoru Sasaki
  • Publication number: 20100113780
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
    Type: Application
    Filed: November 25, 2009
    Publication date: May 6, 2010
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa, Koji Fuji
  • Publication number: 20100105709
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8?, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases.
    Type: Application
    Filed: November 25, 2009
    Publication date: April 29, 2010
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa, Koji Fuji
  • Publication number: 20100056526
    Abstract: A compound represented by the formula (I): wherein R1 is an oxo group, ?N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of circulatory diseases, metabolic diseases and/or central nervous system diseases.
    Type: Application
    Filed: November 21, 2007
    Publication date: March 4, 2010
    Inventors: Takanobu Kuroita, Hiroki Sakamoto, Hideyuki Igawa, Minoru Sasaki, Kouhei Asano, Tsuyoshi Maekawa