Patents by Inventor Hiroki Sakoh

Hiroki Sakoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives
    Publication number: 20080103178
    Abstract: The invention provides the compounds represented by the formula (I) in which, R stands for a dihydroxy-substituted C1-C6 alkyl group, and Cy stands for an optionally substituted C6-C10 bi- or tri-cyclic aliphatic carbocyclic group. These compounds act as nociceptin receptor antagonist, and are useful, for example, as relievers against tolerance to narcotic analgesic, dependence on narcotic analgesic or addiction; analgesic enhancers; antiobestic or appetite suppressors; treating or prophylactic agents for cognitive impairment and dementia/amnesia; agents for treating developmental cognitive abnormality; remedy for schizophrenia; agents for treating neurodegenerative diseases; anti-depressant or treating agents for affective disorder; treating or prophylactic agents for diabetes insipidus; treating or prophylactic agents for polyuria; and remedy for hypotension and the like.
    Type: Application
    Filed: October 11, 2007
    Publication date: May 1, 2008
    Inventors: Masaya Hashimoto, Yoshikazu Iwasawa, Hiroshi Kawamoto, Hisashi Ohta, Satoshi Ozaki, Takeshi Sagara, Hiroki Sakoh, Atsushi Satoh
  • N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives
    Patent number: 7300947
    Abstract: The invention provides the compounds represented by the formula (I) in which, R stands for a dihydroxy-substituted C1-C6 alkyl group, and Cy stands for an optionally substituted C6-C10 bi- or tri-cyclic aliphatic carbocyclic group. These compounds act as nociceptin receptor antagonist, and are useful, for example, as relievers against tolerance to narcotic analgesic, dependence on narcotic analgesic or addiction; analgesic enhancers; antiobestic or appetite suppressors; treating or prophylactic agents for cognitive impairment and dementia/amnesia; agents for treating developmental cognitive abnormality; remedy for schizophrenia; agents for treating neurodegenerative diseases; anti-depressant or treating agents for affective disorder; treating or prophylactic agents for diabetes insipidus; treating or prophylactic agents for polyuria; and remedy for hypotension and the like.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: November 27, 2007
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Masaya Hashimoto, Yoshikazu Iwasawa, Hiroshi Kawamoto, Hisashi Ohta, Satoshi Ozaki, Takeshi Sagara, Hiroki Sakoh, Atsushi Satoh
  • N-dihydroxyalkyl-substituted 2-oxo-imidazole derivatives
    Publication number: 20070015792
    Abstract: The invention provides the compounds represented by the formula (I) in which, R stands for a dihydroxy-substituted C1-C6 alkyl group, and Cy stands for an optionally substituted C6-C10 bi- or tri-cyclic aliphatic carbocyclic group. These compounds act as nociceptin receptor antagonist, and are useful, for example, as relievers against tolerance to narcotic analgesic, dependence on narcotic analgesic or addiction; analgesic enhancers; antiobestic or appetite suppressors; treating or prophylactic agents for cognitive impairment and dementia/amnesia; agents for treating developmental cognitive abnormality; remedy for schizophrenia; agents for treating neurodegenerative diseases; anti-depressant or treating agents for affective disorder; treating or prophylactic agents for diabetes insipidus; treating or prophylactic agents for polyuria; and remedy for hypotension and the like.
    Type: Application
    Filed: July 11, 2006
    Publication date: January 18, 2007
    Inventors: Masaya Hashimoto, Yoshikazu Iwasawa, Hiroshi Kawamoto, Hisashi Ohta, Satoshi Ozaki, Takeshi Sagara, Hiroki Sakoh, Atsushi Satoh