Patents by Inventor Hiroki Satake

Hiroki Satake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CLDN4/anti-CD137 bispecific antibody
    Patent number: 12227586
    Abstract: An object of the present invention is to provide an anti-CLDN4/anti-CD137 bispecific antibody usable in treatment of cancer. An anti-CLDN4/anti-CD137 bispecific antibody produced using an anti-CLDN4 antibody binding to CLDN4 and an anti-CD137 antibody binding to CD137 had agonistic activity for CD137, promoted production of interferon ? by a T cell, and exhibited cytotoxic activity against a cancer cell expressing CLDN4 on a cell surface thereof. Besides, it was shown that the anti-CLDN4/anti-CD137 bispecific antibody can be safely administered to monkeys. Therefore, the anti-CLDN4/anti-CD137 bispecific antibody is usable in treatment of human cancer.
    Type: Grant
    Filed: April 21, 2022
    Date of Patent: February 18, 2025
    Assignees: Astellas Pharma Inc., National Cancer Center
    Inventors: Yoshiyuki Tenda, Masatoshi Yuri, Shigenori Yagi, Yoshiki Satake, Kazunori Hirayama, Hiroki Shirai, Hiroki Sasaki, Fumiko Chiwaki, Masayuki Komatsu
  • Method for analyzing tendency of operation of moving object, operation control system and its constituent apparatus, and recorded medium
    Patent number: 7079927
    Abstract: An operation management system includes a sensor section for detecting behavior of a vehicle, a recorder section for recording the behavior detected by the sensor section on a memory card, and a behavior analyzer for setting a condition pattern for determining the behavior of vehicle as dangerous behavior. The recorder section compares a condition pattern for recognizing the behavior of a vehicle as dangerous behavior with the behavior actually detected by the sensor section, and records only information relating to behavior compatible with the condition pattern on the memory card by dangerous behavior, and statistically analyzes it using the behavior analyzer.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: July 18, 2006
    Assignee: Data Tec Co., Ltd.
    Inventors: Michiyasu Tano, Tsutomu Miyasaka, Kohei Tojo, Hiroki Satake, Reiko Umeda