Abstract: A guide pipe provided along a movement path of a wire electrode between a direction change pulley and a winding device and guiding the wire electrode has antistatic properties. A gas-liquid mixed fluid is supplied into the guide pipe. A suction nozzle passes between a pair of rollers of the winding device and is directly or indirectly connected to an outlet side of the guide pipe. The suction nozzle suctions the gas-liquid mixed fluid in the guide pipe and a tip of the wire electrode by a suction device and captures the wire electrode. The captured wire electrode is wound by the winding device.

Abstract: The present invention is a semiconductor nanoparticle composed of a semiconductor crystal of a compound containing Ag, Au and S as essential constitutional elements. A AgAuS-based compound constituting the semiconductor nanoparticle has a total content of Ag, Au and S of 95 mass % or more. In addition, the compound is preferably a AgAuS ternary compound represented by the general formula Ag(nx)Au(ny)S(nz). In the formula, n is any positive integer. x, y and z represent proportions of the number of atoms of the respective atoms of Ag, Au and S in the compound and are real numbers satisfying 0<x, y, z?1, and x/y is 1/7 or more and 7 or less.

Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: A storage device of a noise inspection apparatus is configured to store a neural network machine-learned to receive, as inputs, an original sound characteristic value indicating a characteristic of sound generated by a transmission and an evaluation sound characteristic value indicating a characteristic of sound that reaches a vehicle cabin, and output a route part characteristic value that is a value indicating a characteristic of a vibration transfer of a vehicle part positioned on a vibration transfer route from the transmission to the vehicle cabin. An execution device of the noise inspection apparatus is configured to calculate, as an estimated value of the route part characteristic value, an output of the neural network that has received, as inputs, measured values of the original sound characteristic value and the evaluation sound characteristic value.

Abstract: A decorative molded component includes: a substrate having a shell extending along a mating surface and a through hole adjacent to the shell and defined along the mating surface; and a molded body coated to the mating surface, the molded body covering the through hole to be continuous from a skin bonded to the shell. The decorative molded component improves appearance while keeping the functions of the two members.

Abstract: The present disclosure provides an inorganic/organic hybrid complementary semiconductor device that can be manufactured at a lower cost, has excellent long-term stability, has a well-balanced operation between the p-type transistor and the n-type transistor, and operates at a high speed.

Abstract: Provided are a substrate processing device, a polishing device, and a substrate processing method. The substrate processing device includes a processing module for processing the substrate with a liquid, and a gas-liquid separation tank connected to the exhaust outlet of the processing module, which separates the liquid from the exhaust received from the processing module and releases the exhaust into an exhaust duct. The gas-liquid separation tank includes a tank body, a heat exchanger arranged inside the tank body and cools the exhaust, and an air nozzle arranged inside the tank body and supplies air to cool the exhaust.

Abstract: An embodiment of the present invention provides an optical film (10) including a light-transmitting base material (11), a hard coat layer (12), and an inorganic layer (13) in this order, wherein the hard coat layer (12) is in contact with the inorganic layer (13), the hard coat layer (12) contains a binder resin (12A) and inorganic particles (12B), the hard coat layer (12) has a film thickness of 1 ?m or more, and the hard coat layer (12) has an indentation hardness of 200 MPa or more.

Abstract: The various examples presented herein are directed to compounds of the formula A-L1-Het1-L2-Cy1 or a pharmaceutical acceptable salt, polymorph, prodrug, solvate or clathrate thereof, wherein: A is cycloalkyl, aryl, arylalkyl or heterocyclyl; Het1 is heterocyclyl containing at least two heteroatoms; Cy1 is a heterocyclyl; L1 is a bond, alkyl, alkenyl or alkynyl linker; L2 is an acyl or alkyl linker; and A and Cy1 are different. The compounds are useful in the treatment of fibrotic diseases, abnormal vascular leak and pathological angiogenesis.

Abstract: The present invention relates to a metal wiring, to be formed on a flexible substrate, including a sintered body of silver particles. The sintered body constituting the metal wiring has a volume resistivity of 20 ??·cm or less, hardness of 0.38 GPa or less, and a Young's modulus of 7.0 GPa or less. A conductive sheet provided with the metal wiring can be produced by applying/calcinating, on a substrate, a metal paste containing, as a solid content, silver particles having prescribed particle size and particle size distribution, and further containing, as a conditioner, an ethyl cellulose having a number average molecular weight of 10,000 or more and 90,000 or less. The metal wiring of the present invention is excellent in bending resistance with change in electrical characteristics suppressed even through repetitive bending deformation.

Abstract: Provided is a separation and recovery apparatus for continuously separating and recovering, from a resin mixture containing a resin containing a hydrolyzable polymer and a resin containing a nonhydrolyzable polymer, a hydrolytic component a of the hydrolyzable polymer A and the nonhydrolyzable polymer B, the apparatus including: a crushing unit that crushes the resin mixture a melting/discharging unit that melts a crushed product obtained by the crushing unit to form a fluid and discharges the fluid at a high pressure; and a hydrothermal reaction treatment unit that continuously subjects the fluid discharged from the melting/discharging unit to a hydrothermal reaction treatment, wherein, in the melting/discharging unit, the hydrolyzable polymer A is hydrolyzed, and the hydrolytic component a thereof is dissolved and transferred into water permeating a sintered alloy diaphragm, thereby separating the nonhydrolyzable polymer B.

Abstract: An auxiliary power supply unit includes an auxiliary power supply device and a downstream power supply line group connecting the auxiliary power supply device to motor units. The auxiliary power supply device includes: an auxiliary power supply provided on a power supply path; and a switching circuit configured to switch the connection state of the auxiliary power supply to the power supply path. The connection state of the auxiliary power supply includes a boost state in which the auxiliary power supply is connected in series with the external power supply. The downstream power supply line group includes branch first downstream drive lines and branch second downstream drive lines. Each of the upstream ends of the branch first downstream drive lines and the branch second downstream drive lines is connected to the power supply path at a position downstream of the auxiliary power supply.

Abstract: There is provided a component replacement method comprising: a) connecting a component replacement device to a chamber of a processing device configured to process a substrate; b) inserting an end effector disposed at a tip end of a transfer arm in the component replacement device into the chamber, and measuring a first distance from a predetermined position in the chamber to the end effector using a distance sensor provided on the end effector; c) moving the end effector until a difference between the first distance and a predetermined second distance becomes less than a predetermined third distance; d) capturing a feature disposed at a predetermined position in the chamber by a camera provided on the end effector; e) moving the end effector so that the feature is captured in a predetermined position in an image captured by the camera; and f) replacing a component in the chamber using the end effector with reference to a position of the end effector in a state where the feature is captured in the predetermin

Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: The present disclosure provides a sealing material suitable for a compound having a non-stoichiometric composi263tion. The present disclosure is related to a sealing material for a compound having a non-stoichiometric composition, the sealing material including a polymer layer and an inorganic oxide insulator layer, wherein the polymer layer includes a first polymer layer containing an organic solvent soluble polymer.

Abstract: A tire can include a pair of beads, a carcass, an inner liner, and an insulation located between the carcass and the inner liner. The carcass can include one carcass ply. The carcass ply can include a plurality of carcass cords and a topping rubber. Each carcass cord can have a total fineness of not less than 6000 dtex and not greater than 9000 dtex. The insulation can be located between first and second beads. A ratio (ta/td) of a thickness to of the topping rubber located between the insulation and the carcass cords to a thickness td of the insulation can be not less than 0.2 and not greater than 0.6.

Abstract: A sensor interface circuit includes: an RF switch having a control node; a bias circuit electrically connected to the control node and applying, to the control node, a voltage at a first level or a second level corresponding to a linear region of a reflection characteristic; a first variable oscillation circuit electrically connectable to a first sensor; a second variable oscillation circuit electrically connectable to a second sensor; and a difference circuit electrically connected between the first variable oscillation circuit and the bias circuit, and between the second variable oscillation circuit and the bias circuit.

Abstract: A power conversion device includes a power converter to output AC power by converting input DC power, an electric leakage detector to detect electric leakage in a power supply line through which the AC power output by the power converter flows when the AC power is being output by the power converter, and a power conversion controller configured to control power conversion of the power converter. The power conversion controller is configured to stop power conversion operation of the power converter based on a detection result of the electric leakage detector.

Abstract: A fabrication method of a thermoelectric conversion element includes forming a first metal layer containing Cu on a first surface of a thermoelectric conversion layer, and forming a first electrode and a first intermediate layer from the first metal layer. The thermoelectric conversion layer is composed of a thermoelectric conversion material containing Mg and at least one kind of element selected from the group consisting of Sb and Bi, the first intermediate layer is provided between the thermoelectric conversion layer and the first electrode, the first intermediate layer is in contact with the thermoelectric conversion layer, the first electrode is in contact with the first intermediate layer, and a composition of the first intermediate layer is different from both a composition of the first electrode and a composition of the thermoelectric conversion layer.

Abstract: A vehicle front recognition apparatus includes an imager that captures an image of an environment ahead of a vehicle on the road, an image analyzer that analyzes the image of the environment with artificial intelligence to segment the image areas of the image by classes to which objects captured in the image belong, and a road information acquirer that acquires high-precision map information ahead of the vehicle. The vehicle front recognition apparatus acquires dynamic information that is not included in the high-precision map information from the classes. The image analyzer includes a feeling-of-strangeness area extractor extracting a feeling-of-strangeness area using the classes from the image areas. The vehicle front recognition apparatus further includes a feeling-of-strangeness area verifier that verifies whether the vehicle can pass through the feeling-of-strangeness area and a notifier that notifies a driver when the vehicle cannot pass through the feeling-of-strangeness area.