Patents by Inventor Hiroki Shigematsu

Hiroki Shigematsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Temperature responsive adsorbent having a strong cation exchange group and method for producing the same
    Patent number: 9643173
    Abstract: Provided is a temperature responsive adsorbent prepared by immobilizing a copolymer containing at least N-isopropylacrylamide to a base material surface. The copolymer has at least a strong cation exchange group. In addition, the copolymer contains the strong cation exchange group in an amount of 0.01 to 5 mol % relative to N-isopropylacrylamide in terms of monomer.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: May 9, 2017
    Assignee: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Ichiro Koguma, Hiroki Shigematsu, Kazuo Okuyama, Teruo Okano, Yoshikatsu Akiyama, Kenichi Nagase
  • Temperature responsive adsorbent having a strong cation exchange group and method for producing the same
    Patent number: 9643174
    Abstract: Provided is a temperature responsive adsorbent prepared by immobilizing a copolymer containing at least N-isopropylacrylamide to a base material surface. The copolymer has at least a strong cation exchange group. In addition, the copolymer contains the strong cation exchange group in an amount of 0.01 to 5 mol % relative to N-isopropylacrylamide in terms of monomer.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: May 9, 2017
    Assignee: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Ichiro Koguma, Hiroki Shigematsu, Kazuo Okuyama, Teruo Okano, Yoshikatsu Akiyama, Kenichi Nagase
  • HIGHLY-PURIFIED SOLUBLE THROMBOMODULIN AND METHOD FOR PRODUCING SAME
    Publication number: 20150322133
    Abstract: Highly-purified soluble thrombomodulin which has a content of host cell-originated proteins being in a ratio of less than 10 ng of the proteins per 10,000 U of the soluble thrombomodulin, wherein the soluble thrombomodulin is produced by a transformant cell obtained by transfecting a host cell with a DNA containing a nucleotide sequence encoding the soluble thrombomodulin.
    Type: Application
    Filed: July 28, 2015
    Publication date: November 12, 2015
    Applicant: ASAHI KASEI PHARMA CORPORATION
    Inventors: Yuji UENO, Hiroki SHIGEMATSU
  • Highly-purified soluble thrombomodulin and method for producing same
    Patent number: 9127089
    Abstract: Highly-purified soluble thrombomodulin which has a content of host cell-originated proteins being in a ratio of less than 10 ng of the proteins per 10,000 U of the soluble thrombomodulin, wherein the soluble thrombomodulin is produced by a transformant cell obtained by transfecting a host cell with a DNA containing a nucleotide sequence encoding the soluble thrombomodulin.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: September 8, 2015
    Assignee: ASAHI KASEI PHARMA CORPORATION
    Inventors: Yuji Ueno, Hiroki Shigematsu
  • TEMPERATURE RESPONSIVE ADSORBENT HAVING A STRONG CATION EXCHANGE GROUP AND METHOD FOR PRODUCING THE SAME
    Publication number: 20150080484
    Abstract: Provided is a temperature responsive adsorbent prepared by immobilizing a copolymer containing at least N-isopropylacrylamide to a base material surface. The copolymer has at least a strong cation exchange group. In addition, the copolymer contains the strong cation exchange group in an amount of 0.01 to 5 mol % relative to N-isopropylacrylamide in terms of monomer.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 19, 2015
    Applicant: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Ichiro KOGUMA, Hiroki SHIGEMATSU, Kazuo OKUYAMA, Teruo OKANO, Yoshikatsu AKIYAMA, Kenichi NAGASE
  • METHOD FOR IMMOBILIZING TEMPERATURE RESPONSIVE PROTEIN A
    Publication number: 20130317172
    Abstract: A method for manufacturing a carrier having temperature responsive protein A, which is protein A mutated such that a binding property to an antibody changes depending upon temperature, immobilized thereto, wherein the temperature responsive protein A has the binding property to the antibody in a first temperature region and no binding property to the antibody in a second temperature region; and the method comprises a step of immobilizing the temperature responsive protein A to a carrier surface at a temperature within the first temperature region in which the temperature responsive protein A has the binding property to the antibody.
    Type: Application
    Filed: December 26, 2011
    Publication date: November 28, 2013
    Applicants: NOMADIC BIOSCIENCE CO., LTD., ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Ichiro Koguma, Hiroki Shigematsu, Kazuo Okuyama, Satoshi Sato
  • TEMPERATURE RESPONSIVE ADSORBENT HAVING A STRONG CATION EXCHANGE GROUP AND METHOD FOR PRODUCING THE SAME
    Publication number: 20130317129
    Abstract: Provided is a temperature responsive adsorbent prepared by immobilizing a copolymer containing at least N-isopropylacrylamide to a base material surface. The copolymer has at least a strong cation exchange group. In addition, the copolymer contains the strong cation exchange group in an amount of 0.01 to 5 mol % relative to N-isopropylacrylamide in terms of monomer.
    Type: Application
    Filed: December 19, 2011
    Publication date: November 28, 2013
    Applicant: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Ichiro Koguma, Hiroki Shigematsu, Kazuo Okuyama, Teruo Okano, Yoshikatsu Akiyama, Kenichi Nagase
  • HIGHLY-PURIFIED SOLUBLE THROMBOMODULIN AND METHOD FOR PRODUCING SAME
    Publication number: 20130143790
    Abstract: Highly-purified soluble thrombomodulin which has a content of host cell-originated proteins being in a ratio of less than 10 ng of the proteins per 10,000 U of the soluble thrombomodulin, wherein the soluble thrombomodulin is produced by a transformant cell obtained by transfecting a host cell with a DNA containing a nucleotide sequence encoding the soluble thrombomodulin.
    Type: Application
    Filed: April 28, 2011
    Publication date: June 6, 2013
    Applicant: ASAHI KASEI PHARMA CORPORATION
    Inventors: Yuji Ueno, Hiroki Shigematsu