Abstract: An information processing device includes: a satellite image acquisition section that is configured to acquire a satellite image captured by an artificial satellite; a weather information acquisition section that is configured to acquire weather information for a region corresponding to the satellite image; and an information output section that is configured to output information relating to a road surface condition for the region, which is estimated based on the satellite image and the weather information.

Abstract: An in-vehicle device as an information processing device includes an acquisition unit that acquires the latest satellite image of a region including a traveling road of a vehicle at predetermined time intervals, a detection unit that detects at least one of a change in the shape of the traveling road and an obstacle on the traveling road based on the satellite image acquired by the acquisition unit, and an output unit that outputs a detection result by the detection unit.

Abstract: Provided is a novel nanoparticle, a contrast agent for magnetic resonance imaging containing the same, and a zwitterionic ligand compound used in production of the nanoparticle. The contrast agent for MRI of the present invention can be suitably used as a contrast agent for MRI in a medical field. The nanoparticle and the zwitterionic ligand compound of the present invention are applicable to various pharmaceutical compositions and the like, including a contrast agent for MRI, and can be used widely in the fields of pharmaceuticals, biotechnology, and the like, including various diagnosis methods and examination reagents.

Abstract: Provided is a conjugate comprising a ligand, a spacer, and a peptide linker useful for an in-vivo diagnostic drug and internal radiation therapy, using an anti-human MUC1 antibody Fab fragment whose binding activity is not attenuated even by labeling with a metal, a fluorescent dye, or the like. A conjugate comprising 3arm DOTA, a specific spacer, a specific peptide linker, and a biomolecule including an anti-human MUC1 antibody Fab fragment, wherein the binding activity thereof is not attenuated even by labeling with a metal, a fluorescent dye, or the like, can be used as a diagnostic composition and/or a pharmaceutical composition.

Abstract: Provided is a conjugate comprising a ligand, a spacer, and a peptide linker useful for an in-vivo diagnostic drug and internal radiation therapy, using an anti-human CEACAM5 antibody Fab fragment whose binding activity is not attenuated even by labeling with a metal, a fluorescent dye, or the like. A conjugate comprising an anti-human CEACAM5 antibody Fab fragment and a ligand, the fragment comprising a heavy chain fragment including a heavy chain variable region consisting of a specific amino acid sequence and a light chain including a light chain variable region consisting of a specific amino acid sequence, or a conjugate comprising a ligand, a spacer, and a peptide linker, wherein the binding activity thereof is not attenuated even by labeling with a metal, a fluorescent dye, or the like, can be used as a diagnostic composition and/or a pharmaceutical composition.

Abstract: [Problem] A novel method for producing a nanoparticle having a metal particle which contains iron oxide to which one or more hydrophilic ligands are coordination bonded is provided, where the nanoparticle is useful as a contrast agent for magnetic resonance imaging. [Means for Solution] As the novel method for producing a nanoparticle having a metal particle which contains iron oxide to which one or more hydrophilic ligands are coordination bonded, by performing ligand exchange to a hydrophilic ligand from an iron oxide nanoparticle having a surface to which a hydrophobic ligand is coordination bonded in one step using a phase transfer catalyst, it is possible to expect shortening of production processes and reduction of hydrophilic ligands used. Furthermore, by producing an iron oxide nanoparticle having a surface to which a hydrophobic ligand is coordination bonded using a dropwise addition method, it is possible to avoid a rapid temperature rise and a reaction at a high temperature of 200° C.

Abstract: A method of winding a belt-shaped member is used in winding a tire member around a forming drum. A position of a leading end of a tire member is detected to obtain a shifted distance of the leading end relative to the forming drum. The leading end is then transferred to the forming drum, while the leading end is being moved in a width direction to make zero the shifted distance. The leading end is pressed against the forming drum, while the leading end is brought into coincidence with a reference position of the forming drum. The forming drum is then rotated during which the tire member is supplied onto the forming drum. A position of a trailing end of the tire member is detected to obtain a shifted distance of the trailing end relative to the reference position of the forming drum. The trailing end is the supplied onto the rotating forming drum, while the trailing end is moved in a width direction to make zero the shifted distance of the trailing end.

Abstract: A cutting apparatus for sheet-like materials comprises a traveling mechanism having a traveling support member movable above a sheet-like material, a cutting device hanged from the traveling support member of the traveling mechanism and movable in directions perpendicular to traveling directions of the traveling support member, a first detecting device for detecting positions of the cutting device in the traveling directions of the traveling support member, a second detecting device for detecting positions of the cutting device in directions perpendicular to the traveling directions of the traveling support member, and an arithmetic unit for arithmetically operating positions of the cutting device on co-ordinates with the aid of signals from the first and second detecting devices.