Patents by Inventor Hiroko Kon

Hiroko Kon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Piperazinyl 1,2,4-benzothiadiazine 1,1-dioxide derivatives their compositions and method of use
    Patent number: 4029780
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 represents a hydrogen atom or a lower alkyl group, and R.sub.2 represents a hydrogen or halogen atom or a trifluoromethyl group,And its pharmaceutically acceptable salt. The compound is prepared by reacting the corresponding 1,2,4-benzothiadiazine 1,1-dioxide with a piperazine compound or alkylating 1,2,4-benzothiadiazine 1,1-dioxide whose corresponding 3-position is substituted by a piperazinyl group. The above compound has superior antihypertensive activity separated from diuretic, antidiuretic and hyperglycemic activities, and is free from side-effects.
    Type: Grant
    Filed: October 28, 1975
    Date of Patent: June 14, 1977
    Assignee: Dainippon Pharmaceutical Co., Ltd.
    Inventors: Haruki Nishimura, Masanao Shimizu, Naonobu Hatano, Katsuyoshi Nakatsuzi, Hiroaki Kinugasa, Hiroko Kon