Patents by Inventor Hiroko Matsunaga
Hiroko Matsunaga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12163809Abstract: A resolver body including a rotor having Nx (Nx is a natural number) salient poles, a stator facing the rotor and having Ns (Ns is an integer equal to or larger than 3) teeth arranged in a circumferential direction, and an excitation winding and two phases of output windings wound on each tooth; and an excitation circuit configured to apply voltage to the excitation winding. The excitation winding and the two phases of output windings wound on each of Nsm (Nsm is an integer equal to or larger than 2) teeth among the Ns teeth are set to be of a main system. The excitation winding and the two phases of output windings wound on each of Ns-Nsm teeth are set to be of a sub-system. The number Nsm of the teeth corresponding to the main system is larger than the number Ns-Nsm of the teeth corresponding to the sub-system.Type: GrantFiled: April 9, 2020Date of Patent: December 10, 2024Assignee: Mitsubishi Electric CorporationInventors: Hiroko Ikeda, Shohei Fujikura, Tatsuya Mori, Kenji Ikeda, Kenta Kubo, Toshihiro Matsunaga
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Patent number: 12152914Abstract: To solve a problem that the accuracy of angle detection deteriorates owing to noise voltage generated by eccentricity or variation in shape among rotors according to the number of magnetic poles of a rotor core of a multiple-system rotation sensor, the number S of magnetic poles of a stator core is, with the number R of the magnetic poles of the rotor core and the number N (N is a natural number equal to or larger than 2) of systems for stator windings, in a relationship of S=nRN (n is a natural number), system windings of each system are wound so as to be divided for every R magnetic poles among the S magnetic poles of the stator core, and a winding arrangement of the system windings of each system is made so as to achieve R-times rotational symmetry about a rotor rotation axis.Type: GrantFiled: April 9, 2020Date of Patent: November 26, 2024Assignee: Mitsubishi Electric CorporationInventors: Shohei Fujikura, Hiroko Ikeda, Tatsuya Mori, Kenji Ikeda, Kenta Kubo, Toshihiro Matsunaga
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Patent number: 12085418Abstract: To provide an abnormality detection apparatus for resolver which can determine the abnormality of at least the first system, even if the period of the excitation AC voltage of the first system and the period of the excitation AC voltage of the second system are different periods, and the magnetic interference between systems occurs. An abnormality detection apparatus for resolver applies an AC voltage of a first period to a first system excitation winding; applies an AC voltage of a second period different from the first period to a second system excitation winding; calculates DC values of first system two output signals by performing a DC extraction processing; and determines abnormality of first system based on whether or not the DC values of first system two output signals are within a normal range.Type: GrantFiled: February 26, 2020Date of Patent: September 10, 2024Assignee: Mitsubishi Electric CorporationInventors: Tatsuya Mori, Hiroko Ikeda, Toshihiro Matsunaga, Kenji Ikeda, Kenta Kubo
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Patent number: 12068702Abstract: In an electric motor control device which controls rotation of an AC electric motor having two sets of three-phase windings and provided with a resolver having two systems by calculating voltage command values on dq axes, dq conversion of currents of first three-phase windings is performed using a first angle calculated from output of the first system of the resolver, and dq conversion of currents of second three-phase windings is performed using a second angle calculated from output of the second system of the resolver. With both d-axis current command values set at the same value, respective voltage command values on dq axes are calculated and respectively converted into voltage command values for voltage application to the first three-phase windings, using the first angle, and converted into voltage command values for voltage application to the second three-phase windings, using the second angle.Type: GrantFiled: May 19, 2020Date of Patent: August 20, 2024Assignee: Mitsubishi Electric CorporationInventors: Masahiko Orii, Tatsuya Mori, Hiroko Ikeda, Toshihiro Matsunaga, Kenji Ikeda, Kenta Kubo
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Publication number: 20180073023Abstract: An object of the present invention is to provide a circular single-stranded nucleic acid, and a method for preparing the same and a method for using the same. A circular single-stranded nucleic acid according to one embodiment of the present invention is a circular single-stranded nucleic acid for determining a target base on a genomic DNA, and includes a first single-stranded nucleic acid which has the target base or a complementary base thereto and is a part of one of the strands of the genomic DNA, and a second single-stranded nucleic acid which has an index sequence to serve as an index of a cell, from which the genomic DNA is derived, or a complementary sequence thereto.Type: ApplicationFiled: August 30, 2017Publication date: March 15, 2018Inventors: Hiroko MATSUNAGA, Maiko TANABE
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Publication number: 20160333397Abstract: A reaction liquid after a nucleic acid amplification reaction is made suitable for various processes. A step of measuring the amount of a target product and the amount of a byproduct after performing a nucleic acid amplification reaction, and a step of determining that a process for removing the byproduct is needed when the abundance ratio of the target product to the byproduct is lower than a prescribed value, and determining the dilution ratio of a reaction liquid after the nucleic acid amplification reaction when the abundance ratio is higher than the prescribed value are included.Type: ApplicationFiled: January 27, 2014Publication date: November 17, 2016Applicant: HITACHI, LTD.Inventors: Hiroko Matsunaga, Tomoharu Kajiyama, Mari Ohta, Hideki Kambara
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Publication number: 20140065704Abstract: The present invention provides a simple and highly reliable cell collection system with high throughput and improved in cell collection efficiency. In the present invention, one or more pores are formed in a cell collection plate. One surface of the plate can be directly introduced in e.g., a petri dish, so as to be in contact with a solution containing cells. In this case, means for obtaining an optical image of collected cells from its rear surface is provided to improve reliability and convenience during a cell collection process. Alternatively, the vicinities of the pores in the cell collection plate are only hydrophilized and the other region is made water repellent to improve the efficiency of cell collection.Type: ApplicationFiled: April 10, 2012Publication date: March 6, 2014Inventors: Masataka Shirai, Hiroyuki Tsunoda, Hiroko Matsunaga, Kenko Uchida
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Publication number: 20080318244Abstract: It is intended to provide a technique for amplifying, individually and in parallel, nucleic acids contained in a mixture of plural kinds of nucleic acid samples. The present invention provides a nucleic acid analysis method comprising amplification means, whereby amplification reaction is performed in a reaction solution comprising a homogeneous solvent and comprising at least plural template nucleic acids and solid phase carriers comprising one or more kinds of amplification probes immobilized on the surface, to prevent amplified products attributed to two or more template nucleic acids from being replicated in one solid phase carrier. According to the present invention, plural kinds of analyte nucleic acid samples in a mixed state can be amplified individually and in parallel. This method achieves one solid phase carrier-one nucleic acid. Therefore, a higher density of solid phase carriers with obtained amplified products is easily achieved, leading to improved throughput of amplified product analysis.Type: ApplicationFiled: June 19, 2008Publication date: December 25, 2008Inventors: Hiroko Matsunaga, Hideki Kambara, Tomoharu Kajiyama
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Patent number: 7214781Abstract: A method for the diagnosis and identification of new or residual lung cancer is disclosed which uses newly identified markers for lung cancer including syndecan 1, collagen 1 alpha 2, and two novel proteins, 7013 and 7018. The method involves identification of the lung cancer markers is blood from a patient. It is envisioned that at least one marker may be used or any mixture of the four. The method may also include the identification of cytokeratin-19.Type: GrantFiled: June 21, 2001Date of Patent: May 8, 2007Assignees: Hitachi Chemical Research Center, Inc., Hitachi Chemical Co., Ltd.Inventors: Masato Mitsuhashi, Hiroko Matsunaga, Hideki Kambara, Masafumi Kawamura
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Publication number: 20060275783Abstract: A method for the diagnosis and identification of new or residual lung cancer is disclosed which uses newly identified markers for lung cancer including syndecan 1, collagen 1 alpha 2, and two novel proteins, 7013 and 7018. The method involves identification of the lung cancer markers is blood from a patient. It is envisioned that at least one marker may be used or any mixture of the four. The method may also include the identification of cytokeratin-19.Type: ApplicationFiled: October 19, 2005Publication date: December 7, 2006Inventors: Masato Mitsuhashi, Hiroko Matsunaga, Hideki Kambara, Masafumi Kawamura
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Publication number: 20060223087Abstract: A simple and highly accurate method for detecting the presence or absence of gene mutation and methylated cytosine in CpG dinucleotide that are contained in a target sequence derived from an analysis sample is provided. Features of the method for nucleic acid analysis include cleaving one or more noncomplementary sites in a double-stranded nucleic acid sample by a single strand-specific endonuclease, hybridizing at least one of the nucleic acid fragments obtained to a probe containing a nucleotide sequence that is partially or totally identical to either one strand of the double-stranded nucleic acid sample, allowing an extension reaction to proceed from the nucleic acid fragment hybridized to the probe, and optically detecting pyrophosphate generated by the extension reaction, thereby judging the presence or absence of at least a noncomplementary site in the double-stranded nucleic acid sample.Type: ApplicationFiled: January 31, 2006Publication date: October 5, 2006Inventors: Kiyomi Taniguchi, Keiichi Nagai, Hiroko Matsunaga
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Publication number: 20050287549Abstract: This invention provides a method of genetic testing that enables testing of a plurality of variation sites (SNPs) in a cost-effective and simple manner, allowing realization of genetic diagnosis in clinical settings. The SNP type of the nucleic acid sample is evaluated by: allowing a nucleic acid sample having an anchor sequence at its 5? end to hybridize to a support having, immobilized on its surface, a probe containing a sequence that is complementary to the target sequence (the SNP region); extending a complementary strand from the probe utilizing the nucleic acid sample as a template; dissociating and removing the nucleic acid sample from the extended probe; extending a complementary strand using the extended probe as a template and a primer having a sequence identical to the anchor sequence; and detecting pyrophosphoric acid generated via the primer extension, based on bioluminescence.Type: ApplicationFiled: January 25, 2005Publication date: December 29, 2005Inventors: Keiichi Nagai, Kazunori Okano, Hideyuki Noda, Hiroko Matsunaga, Kiyomi Taniguchi, Yoshiaki Yazawa, Tomoharu Kajiyama
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Publication number: 20030215828Abstract: A method for the diagnosis and identification of new or residual lung cancer is disclosed which uses newly identified markers for lung cancer including syndecan 1, collagen 1 alpha 2, and two novel proteins, 7013 and 7018. The method involves identification of the lung cancer markers is blood from a patient. It is envisioned that at least one marker may be used or any mixture of the four. The method may also include the identification of cytokeratin-19.Type: ApplicationFiled: April 4, 2003Publication date: November 20, 2003Inventors: Masato Mitsuhashi, Hiroko Matsunaga, Hideki Kambara, Masafumi Kawamura
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Patent number: 6514702Abstract: There are beforehand prepared a monomer having a reaction residue and a polynucleotide probe set comprising plural kinds of polynucleotide probes having a residue bonded to the reaction residue. The monomer is mixed with each kind of polynucleotide probes comprising any plural probes selected from the polynucleotide probe set. Each kind of the resultant mixtures is added to each of different small holes to make the mixture into gel matrix. Thus, a polynucleotide probe chip is produced. Sample DNA is forcibly migrated in the gels by electrophoresis. Laser light is projected onto the side face of the chip. The fluorescence emitted from the whole surface of the chip is collectively detected with a high-sensitive two-dimensional detector. Thus, the polynucleotide probe chip, holding various kinds of DNA probes, for detecting DNA can be provided. This chip has high hybridization-efficiency and makes high-sensitivity and high-speed DNA detection possible.Type: GrantFiled: September 28, 2000Date of Patent: February 4, 2003Assignee: Hitachi, Ltd.Inventors: Kazunori Okano, Hideki Kambara, Chihiro Uematsu, Hiroko Matsunaga, Takashi Irie, Tomoharu Kajiyama, Kenji Yasuda
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Patent number: 6183970Abstract: There are beforehand prepared a monomer having a reaction residue and a polynucleotide probe set comprising plural kinds of polynucleotide probes having a residue bonded to the reaction residue. The monomer is mixed with each kind of polynucleotide probes comprising any plural probes selected from the polynucleotide probe set. Each kind of the resultant mixtures is added to each of different small holes to make the mixture into gel matrix. Thus, a polynucleotide probe chip is produced. Sample DNA is forcibly migrated in the gels by electrophoresis. Laser light is projected onto the side face of the chip. The fluorescence emitted from the whole surface of the chip is collectively detected with a high-sensitive two-dimensional detector. Thus, the polynucleotide probe chip, holding various kinds of DNA probes, for detecting DNA can be provided. This chip has high hybridization-efficiency and makes high-sensitivity and high-speed DNA detection possible.Type: GrantFiled: August 26, 1999Date of Patent: February 6, 2001Assignee: Hitachi, Ltd.Inventors: Kazunori Okano, Hideki Kambara, Chihiro Uematsu, Hiroko Matsunaga, Takashi Irie, Tomoharu Kajiyama, Kenji Yasuda
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Patent number: 5968743Abstract: The present invention provides a DNA sequencing method comprising: (1) a step of fragmentation of a sample DNA and amplifying each fragment to obtain a first DNA fragment; (2) a step of obtaining from the first DNA fragment a second DNA fragment substantially complementary to the sample DNA at least at the 3' terminus thereof; and (3) a step of performing an extension reaction of complementary strand, using the sample DNA as a template to produce a third DNA fragment containing a base sequence complementary to the second DNA fragment and having a size longer than that of the second DNA fragment, and using the third DNA fragment as a template for sequencing of the sample DNA. DNA sequencing can be proceeded efficiently with extremely low redundancy.Type: GrantFiled: October 9, 1997Date of Patent: October 19, 1999Assignee: Hitachi, Ltd.Inventors: Hiroko Matsunaga, Kazunori Okano, Hideki Kambara