Patents by Inventor Hiroko Miki
Hiroko Miki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240110229Abstract: According to one embodiment, a chemical sensor including a nucleic acid probe for capturing a target substance, a sensor element that has a surface on which the nucleic acid probe is immobilized, and a liquid film that covers the sensor element is provided.Type: ApplicationFiled: March 15, 2023Publication date: April 4, 2024Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Yoshiaki SUGIZAKI, Hiroko MIKI
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Publication number: 20240027350Abstract: A method for inspecting probe molecule includes evaluating the formation of the probe molecule at the surface of the graphene by comparing an intensity ratio a1/b1, and an intensity ratio a2/b2. The intensity al is of a peak of the first Raman spectrum having a peak top positioned in a first band of not less than 1200 cm?1 and not more than 1500 cm?1. The intensity b1 is of a peak of the first Raman spectrum having a peak top positioned in a second band of not less than 1510 cm?1 and not more than 1800 cm?1. The intensity a2 is of a peak of the second Raman spectrum having a peak top positioned in the first band. The intensity b2 is of a peak of the second Raman spectrum having a peak top positioned in the second band.Type: ApplicationFiled: February 21, 2023Publication date: January 25, 2024Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroko MIKI, Yoshiaki SUGIZAKI, Hideyuki TOMIZAWA
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Publication number: 20230304964Abstract: According to one embodiment, an FET sensor includes a sensitive film including a carbon allotrope, a liquid film disposed so as to cover the sensitive film, a source electrode and a drain electrode electrically connected to the sensitive film, and a gate electrode configured to apply an electric field to the sensitive film, wherein the liquid film comprises an antioxidant.Type: ApplicationFiled: September 7, 2022Publication date: September 28, 2023Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Yoshiaki SUGIZAKI, Hiroko MIKI
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Publication number: 20230296576Abstract: Embodiments provide a chemical sensor device that is a chemical sensor using a nucleic acid compound and a specific blocking agent and can detect a target substance with high sensitivity, and a method for detecting a target substance. A chemical sensor device of an embodiment includes a sensitive film, a nucleic add compound that is immobilized on the sensitive film, and a phosphoric acid derivative that is immobilized on a surface of the sensitive film on which the nucleic add compound is immobilized.Type: ApplicationFiled: September 7, 2022Publication date: September 21, 2023Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Yoshiaki SUGIZAKI, Hiroko MIKI
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Publication number: 20230194516Abstract: According to one embodiment, a method for immobilizing a nucleic acid compound on a surface of a sensor element including graphene, graphene oxide, a carbon nanotube, or graphite, the method includes preparing an aqueous solution containing a nucleic acid compound and sodium chloride, wherein the nucleic acid compound includes a polycyclic aromatic moiety including a polycyclic aromatic skeleton and a linker structure bonded to the polycyclic aromatic skeleton, and a nucleic acid moiety bonded to the linker structure, and dropping the aqueous solution onto the surface of the sensor element.Type: ApplicationFiled: September 7, 2022Publication date: June 22, 2023Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroko MIKI, Yoshiaki SUGIZAKI, Hideyuki TOMIZAWA
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Patent number: 11635428Abstract: According to one embodiment, a molecule detecting device includes a capturing section, a releasing section, and a detecting section. The capturing section is configured to, by combining a target molecule and a solubilizing agent with each other and thereby creating a composite body, capture the target molecule in a carrier liquid. The releasing section is configured to make the composite body release the target molecule therefrom in the carrier liquid. The detecting section is configured to carry out detection of the target molecule in the carrier liquid.Type: GrantFiled: September 10, 2020Date of Patent: April 25, 2023Assignee: Kabushiki Kaisha ToshibaInventors: Hiroko Miki, Atsunobu Isobayashi, Yoshiaki Sugizaki
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Publication number: 20220308012Abstract: A chemical sensor module includes first to n-th (n is a natural number of 2 or greater) graphene sensors; and an exposure mechanism exposing the first to n-th graphene sensors to first to n-th aqueous solutions containing a sample substance and having different concentrations of phosphate ion, magnesium ion, or sulfate ion. The chemical sensor module identifies the sample substance from the difference in electrical characteristics of the first to n-th graphene sensors.Type: ApplicationFiled: August 20, 2021Publication date: September 29, 2022Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Yoshiaki SUGIZAKI, Hiroko MIKI
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Publication number: 20220298550Abstract: A chemical sensor device includes a sensor element; an oligopeptide mounted on a surface of the sensor element, the oligopeptide containing a first peptide sequence forming a ?-sheet structure and a cysteine residue at a position different from the first peptide sequence; and a probe that is bonded to the cysteine residue and binds to or reacts with a specific substance.Type: ApplicationFiled: August 19, 2021Publication date: September 22, 2022Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroko MIKI, Yoshiaki SUGIZAKI, Atsunobu ISOBAYASHI
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Publication number: 20210293802Abstract: According to one embodiment, a molecule detecting device includes a capturing section, a releasing section, and a detecting section. The capturing section is configured to, by combining a target molecule and a solubilizing agent with each other and thereby creating a composite body, capture the target molecule in a carrier liquid. The releasing section is configured to make the composite body release the target molecule therefrom in the carrier liquid. The detecting section is configured to carry out detection of the target molecule in the carrier liquid.Type: ApplicationFiled: September 10, 2020Publication date: September 23, 2021Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hiroko Miki, Atsunobu Isobayashi, Yoshiaki Sugizaki
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Publication number: 20210129083Abstract: An object of the present invention is to provide a filtration apparatus capable of achieving space-saving of the entire apparatus. A filtration apparatus according to the present invention includes a plurality of filtration modules that each include a plurality of hollow fiber membranes that are arranged adjacent to each other so as to extend in an up-down direction, a washing module configured to supply air bubbles from below the plurality of filtration modules, and a frame that supports the plurality of filtration modules. The washing module includes a plurality of aeration tubes each having a plurality of aeration holes. At least a portion of the frame is a hollow tube through which a gas is supplied to the plurality of aeration tubes.Type: ApplicationFiled: January 13, 2017Publication date: May 6, 2021Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiroko MIKI, Keiichi IKEDA, Toru MORITA
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Publication number: 20200094191Abstract: A filtration apparatus according to an aspect of the present invention includes a plurality of filtration modules each including a plurality of hollow fiber membranes aligned so as to extend in an up-and-down direction, a bar-like upper holding member configured to secure upper ends of the hollow fiber membranes, and a bar-like lower holding member configured to secure lower ends of the hollow fiber membranes; a cleaning module configured to supply bubbles from below the filtration modules; a frame including a plurality of vertical frame members disposed to extend in the up-and-down direction and a plurality of lateral frame members disposed to extend in lateral directions, the frame being configured to hold the filtration modules and the cleaning module; and a plurality of lower guide rails configured to engage with the lower holding members and disposed between opposite faces of the lateral frame members, wherein at least part of the cleaning module is suspended from the frame.Type: ApplicationFiled: June 19, 2017Publication date: March 26, 2020Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiroko MIKI, Keiichi IKEDA, Toru MORITA
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Patent number: 10533934Abstract: According to one embodiment, a particle inspection system includes a voltage driving circuit which applies a driving voltage for a particle inspection to a particle inspection chip, a current-voltage conversion circuit which converts, into a voltage signal, a current signal output from the particle inspection chip when the driving voltage is applied to the particle inspection chip, a detection circuit which detects, based on the voltage signal, whether the sample liquid is introduced into a detection region of the particle inspection chip, and an analysis circuit which analyzes the fine particle, in the sample liquid based on the voltage signal. The voltage driving circuit varies the driving voltage based on the detection result of the detection circuit.Type: GrantFiled: January 18, 2017Date of Patent: January 14, 2020Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Michihiko Nishigaki, Hiroshi Hamasaki, Naofumi Nakamura, Kentaro Kobayashi, Hiroko Miki
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Patent number: 10377650Abstract: A membrane separation type activated sludge treatment method according to an aspect of the present invention includes a step of performing biological treatment on waste water and a step of performing membrane separation on water having been treated in the biological treatment step. The membrane separation step employs a plurality of filtration modules including a plurality of hollow fiber membranes arranged adjacent to one another and oriented in one direction and a pair of holding members fixing both ends of the plurality of hollow fiber membranes, and a plurality of cleaning modules supplying air bubbles from beneath the filtration modules. An amount of treated water sucked by the filtration modules and an amount of air bubbles supplied by the cleaning modules are varied in response to variations in an inflow rate of the waste water in the biological treatment step.Type: GrantFiled: September 28, 2016Date of Patent: August 13, 2019Assignee: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiromu Tanaka, Hiroko Miki, Tomoyuki Yoneda, Toru Morita
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Patent number: 10279348Abstract: One of embodiments is a semiconductor micro-analysis chip for detecting particles in a sample liquid. The chip comprises a semiconductor substrate, a first flow channel provided on the semiconductor substrate to allow the sample liquid to flow therein, a second flow channel provided at a different position from the first flow channel of the semiconductor substrate to allow the sample liquid or an electrolyte solution to flow therein, a contact portion where a portion of the first flow channel and a portion of the second flow channel abut each other or intersect one another with a partition being arranged between the flow channels, and a fine hole provided on the partition of the contact portion to allow the particles to pass therethrough.Type: GrantFiled: March 5, 2014Date of Patent: May 7, 2019Assignee: KABUSHIKI KAISHA TOSHIBAInventors: Hiroko Miki, Hideto Furuyama, Kentaro Kobayashi, Akihiro Kojima
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Publication number: 20190062818Abstract: According to one embodiment, a sensor includes an ionic liquid, a probe molecule, and a sensor element. The probe molecule selectively associates with a designated substance in the ionic liquid. The sensor element detects an association of the probe molecule with the designated substance.Type: ApplicationFiled: March 5, 2018Publication date: February 28, 2019Applicant: Kabushiki Kaisha ToshibaInventors: Hiroko Miki, Yoshiaki Sugizaki, Tatsuro Saito, Atsunobu Isobayashi
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Publication number: 20190064157Abstract: According to one embodiment, a detection device is disclosed. The detection device includes a first region, a first electrode on the first region, a second region, a second electrode on the second region, a partition partitioning the first region and the second region and including a through hole, thereby communicating the first region with the second region. The device further includes a probe which binds specifically to the detection target, and is detachably connected to the first electrode, a detacher to detach the probe from the first electrode, a determination unit to determine whether the first liquid contains a detection target based on a change of electrical condition between the first electrode and the second electrode in a state where the first region and the second region are supplied with the first liquid and the second liquid, respectively.Type: ApplicationFiled: February 28, 2018Publication date: February 28, 2019Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Takuya MIYAGAWA, Sadato HONGO, Hiroko MIKI, Hiroshi HAMASAKI, Kentaro KOBAYASHI, Ping WANG, Naofumi NAKAMURA
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Publication number: 20190039025Abstract: An object of the present invention is to provide a filter unit in which hollow fiber membranes can be effectively cleaned. A filter unit of the present invention includes a plurality of filtration modules and one or more air bubble generation modules that supply bubbles to the filtration modules from below. Each filtration modules includes a plurality of hollow fiber membranes extending in an up-down direction and arranged side by side in a curtain shape and which are arranged at intervals. The one or more air bubble generation modules supply coarse bubbles to the filtration modules.Type: ApplicationFiled: October 5, 2016Publication date: February 7, 2019Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiromu TANAKA, Tomoyuki YONEDA, Hiroko MIKI, Toru MORITA
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Publication number: 20180369723Abstract: A method for operating a filtration apparatus according to an aspect of the present invention is a method for operating a filtration apparatus including three or more filtration modules, the method including a filtration step in which a filtration treatment is performed using the filtration modules and a cleaning step in which some of the filtration modules are stopped from performing the filtration treatment and the filtration modules stopped from performing the filtration treatment are cleaned simultaneously. A filtration apparatus according to another aspect of the present invention is a filtration apparatus including three or more filtration modules, a collection system that collects a filtrate from the filtration modules, and a cleaning system that cleans some of the filtration modules simultaneously.Type: ApplicationFiled: January 9, 2017Publication date: December 27, 2018Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiroko MIKI, Hiromu TANAKA, Takayuki NISHIURA, Kenichi USHIKOSHI, Kiyoshi IDA, Toru MORITA
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Publication number: 20180282188Abstract: A membrane separation type activated sludge treatment method according to an aspect of the present invention includes a step of performing biological treatment on waste water and a step of performing membrane separation on water having been treated in the biological treatment step. The membrane separation step employs a plurality of filtration modules including a plurality of hollow fiber membranes arranged adjacent to one another and oriented in one direction and a pair of holding members fixing both ends of the plurality of hollow fiber membranes, and a plurality of cleaning modules supplying air bubbles from beneath the filtration modules. An amount of treated water sucked by the filtration modules and an amount of air bubbles supplied by the cleaning modules are varied in response to variations in an inflow rate of the waste water in the biological treatment step.Type: ApplicationFiled: September 28, 2016Publication date: October 4, 2018Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiromu TANAKA, Hiroko MIKI, Tomoyuki YONEDA, Toru MORITA
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Publication number: 20180243698Abstract: A filter unit according to the present invention includes a plurality of filtration modules and a plurality of air bubble generation modules. Each filtration module includes a plurality of hollow fiber membranes extending in an up-down direction and arranged side by side in a curtain shape and a pair of holding members to which top and bottom ends of the hollow fiber membranes are fixed. The air bubble generation modules discharge bubbles toward the hollow fiber membranes. The filtration modules are arranged in parallel at intervals. each air bubble generation module has a discharge port that is disposed between lower holding members of a pair of adjacent filtration modules and above bottom ends of the lower holding members.Type: ApplicationFiled: June 13, 2016Publication date: August 30, 2018Applicant: SUMITOMO ELECTRIC INDUSTRIES, LTD.Inventors: Hiromu TANAKA, Tomoyuki YONEDA, Hiroko MIKI, Toru MORITA