Patents by Inventor Hiroko Ogawa

Hiroko Ogawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210017176
    Abstract: The present invention provides the compound, 3-[(1S,2S)-1-[5-[(4S)-2,2-Dimethyloxan-4-yl]-2-(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a pharmaceutically acceptable salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound.
    Type: Application
    Filed: October 7, 2020
    Publication date: January 21, 2021
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hitoshi YOSHINO, Satoshi TSUCHIYA, Atsushi MATSUO, Tsutomu SATO, Masahiro NISHIMOTO, Kyoko OGURI, Hiroko OGAWA, Yoshikazu NISHIMURA, Yoshiyuki FURUTA, Hirotaka KASHIWAGI, Nobuyuki HORI, Takuma KAMON, Takuya SHIRAISHI, Shoshin YOSHIDA, Takahiro KAWAI, Satoshi TANIDA, Masahide AOKI
  • Patent number: 10858356
    Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: December 8, 2020
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hitoshi Yoshino, Satoshi Tsuchiya, Atsushi Matsuo, Tsutomu Sato, Masahiro Nishimoto, Kyoko Oguri, Hiroko Ogawa, Yoshikazu Nishimura, Yoshiyuki Furuta, Hirotaka Kashiwagi, Nobuyuki Hori, Takuma Kamon, Takuya Shiraishi, Shoshin Yoshida, Takahiro Kawai, Satoshi Tanida, Masahide Aoki
  • Publication number: 20190225604
    Abstract: The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.
    Type: Application
    Filed: September 26, 2017
    Publication date: July 25, 2019
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hitoshi YOSHINO, Satoshi TSUCHIYA, Atsushi MATSUO, Tsutomu SATO, Masahiro NISHIMOTO, Kyoko OGURI, Hiroko OGAWA, Yoshikazu NISHIMURA, Yoshiyuki FURUTA, Hirotaka KASHIWAGI, Nobuyuki HORI, Takuma KAMON, Takuya SHIRAISHI, Shoshin YOSHIDA, Takahiro KAWAI, Satoshi TANIDA, Masahide AOKI
  • Patent number: 7557113
    Abstract: A compound having GSK-3 inhibitory activity. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when A6 is CR?CR or C?C, wherein R is H or an lower aliphatic hydrocarbon group.
    Type: Grant
    Filed: August 26, 2004
    Date of Patent: July 7, 2009
    Assignee: Teijin Pharma Limited
    Inventors: Takaharu Tsutsumi, Satoshi Sugiura, Masahiro Koga, Yoshiyuki Matsumoto, Toshihiro Ishii, Akira Nakano, Gen Unoki, Yuri Sakai, Reiko Takarada, Hiroko Ogawa
  • Publication number: 20060160831
    Abstract: A compound having GSK-3 inhibitory activity. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when A6 is CR?CR or C?C, wherein R is H or an lower aliphatic hydrocarbon group.
    Type: Application
    Filed: August 26, 2004
    Publication date: July 20, 2006
    Applicant: TEIJIN PHARMA LIMITED
    Inventors: Takaharu Tsutsumi, Satoshi Sugiura, Masahiro Koga, Yoshiyuki Matsumoto, Toshihiro Ishii, Akira Nakano, Gen Unoki, Yuri Sakai, Reiko Takarada, Hiroko Ogawa
  • Publication number: 20050153992
    Abstract: A compound having GSK-3 inhibiting function. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is a hydrogen atom, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and when A6 is CR?CR or C?C; R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl or cyano group; and R is H or an aliphatic hydrocarbon group.
    Type: Application
    Filed: August 26, 2004
    Publication date: July 14, 2005
    Applicant: TEIJIN PHARMA LIMITED
    Inventors: Takaharu Tsutsumi, Satoshi Sugiura, Masahiro Koga, Yoshiyuki Matsumoto, Toshihiro Ishii, Akira Nakano, Gen Unoki, Yuri Sakai, Reiko Takarada, Hiroko Ogawa
  • Publication number: 20030073148
    Abstract: Problems of the present invention are to provide methods for diagnosing the morbid state based on the assay of a human airway trypsin-like protease in a biosample and to provide a therapeutic agent for diseases associated with the human airway trypsin-like protease.
    Type: Application
    Filed: August 2, 2001
    Publication date: April 17, 2003
    Inventors: Hiroshi Eguchi, Kazuyoshi Yamaoka, Hiroko Ogawa, Susumu Yasuoka
  • Patent number: 5804410
    Abstract: This invention provides a nucleic acid sequence encoding a trypsin-like enzyme which can be present at the trachea of human lungs, and can selectively digest a synthetic substrate for trypsin and a synthetic substrate for thrombin, and fibrinogen; and a process for producing the trypsin-like enzyme by genetic engineering utilizing the nucleic acid sequence.
    Type: Grant
    Filed: July 28, 1995
    Date of Patent: September 8, 1998
    Assignee: Teijin Limited
    Inventors: Kazuyoshi Yamaoka, Hiroko Ogawa, Yoshinori Sugimoto, Kenichi Masuda, Tetsuya Suga, Kenichiro Takagi, Susumu Yasuoka
  • Patent number: 4601756
    Abstract: A recording liquid comprises a liquid composition containing water-soluble dyes as coloring component, characterized in that C.I. Food Black 2 and one or more dyes in different color or colors are used in combination as said coloring component.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: July 22, 1986
    Assignee: Canon Kabushiki Kaisha
    Inventors: Masahiro Chiba, Kazuo Iwata, Tadayuki Nakousai, Hiroko Ogawa, Takashi Ohba
  • Patent number: 4244862
    Abstract: Block copolymers of a vinyl-substituted aromatic hydrocarbon and a conjugated diene, having alkali metal atoms linked to at least one terminal of the polymer chain are obtained by polymerizing vinyl-substituted aromatic hydrocarbon and conjugated diene monomers with use of an alkali metal or organo alkali metal initiator. The block copolymer thus obtained is treated with a polar reactant to introduce polar groups into the polymer chain terminal.Compositions for paints and printing inks are prepared by incorporating inorganic pigments into the block copolymer having the terminal polar group.
    Type: Grant
    Filed: November 1, 1977
    Date of Patent: January 13, 1981
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Minoru Handa, Takuzi Nishizawa, Hiroko Ogawa, Shinichiro Asai