Abstract: A living tissue bonding system including: a sandwiching section for sandwiching living tissue; a power source for supplying to the living tissue treatment energy for bonding the living tissue sandwiched by the sandwiching section; a temperature measuring section for measuring a temperature of the living tissue sandwiched by the sandwiching section; a calculation section calculating, from the temperature of the living tissue measured by the temperature measuring section and a time period of applying the treatment energy, a time integral value of the temperature of the living tissue; a comparison section comparing the time integral value of the temperature of the living tissue calculated by the calculation section with a predetermined setting value; and an instruction section giving an instruction based on a result of the comparison by the comparison section.

Abstract: An endoscopic device includes a longitudinal member, a pair of jaws installed at a distal end of the longitudinal member and configured to be freely opened and closed, a first grasping member supported by a first jaw of the pair of jaws, a second grasping member supported by a second jaw of the pair of jaws, the second body having a wire shape, flexibility, and being curved in a loop shape, a long operating transmission member having a distal end portion connected to the pair of jaws and installed to advance and retreat along a longitudinal axis of the longitudinal member, and an open-close operating portion installed at a proximal end portion of the operating transmission member and configured to be manipulated to open and close the pair of jaws.

Abstract: An endoscopic device includes a longitudinal member, a pair of jaws installed at a distal end of the longitudinal member and configured to be freely opened and closed, a first grasping member supported by a first jaw of the pair of jaws, a second grasping member supported by a second jaw of the pair of jaws, the second body having a wire shape, flexibility, and being curved in a loop shape, a long operating transmission member having a distal end portion connected to the pair of jaws and installed to advance and retreat along a longitudinal axis of the longitudinal member, and an open-close operating portion installed at a proximal end portion of the operating transmission member and configured to be manipulated to open and close the pair of jaws.

Abstract: A body fluid collection device includes a long shaft member having a lumen formed along a longitudinal axis, an absorption body configured to expand from an initial state in which a body fluid is not absorbed into the absorption body as the body fluid is absorbed, and having a proximal end portion configured to be disposed in the lumen when a predetermined amount of the body fluid is absorbed into the absorption body, and an identification section configured to indicate that the absorption body has absorbed the predetermined amount of the body fluid.

Abstract: A living tissue bonding system including: a sandwiching section for sandwiching living tissue; a power source for supplying to the living tissue treatment energy for bonding the living tissue sandwiched by the sandwiching section; a temperature measuring section for measuring a temperature of the living tissue sandwiched by the sandwiching section; a calculation section calculating, from the temperature of the living tissue measured by the temperature measuring section and a time period of applying the treatment energy, a time integral value of the temperature of the living tissue; a comparison section comparing the time integral value of the temperature of the living tissue calculated by the calculation section with a predetermined setting value; and an instruction section giving an instruction based on a result of the comparison by the comparison section.

Abstract: An endoscopic device includes a longitudinal member, a pair of jaws installed at a distal end of the longitudinal member and configured to be freely opened and closed, a first grasping member supported by a first jaw of the pair of jaws, a second grasping member supported by a second jaw of the pair of jaws, the second body having a wire shape, flexibility, and being curved in a loop shape, a long operating transmission member having a distal end portion connected to the pair of jaws and installed to advance and retreat along a longitudinal axis of the longitudinal member, and an open-close operating portion installed at a proximal end portion of the operating transmission member and configured to be manipulated to open and close the pair of jaws.

Abstract: A map information system is provided which includes an electronic pen which reads a dot pattern in a form where map images are shown, to output handwriting information, and a processing unit including an association module which associates the output handwriting information with one of the map images where the handwriting information is written and stores it in a storage unit, a search module which searches for the associated handwriting information and map image using information to specify the map image as a search key, a pattern assignment module which when acquiring print request information including information to specify the map images to be printed, newly assigns a dot pattern, and an output instruction module which issues an output instruction so as to cause an output unit to visually output data including the retrieved associated handwriting information and map image and the newly assigned dot pattern.

Abstract: An endoscopic therapeutic device includes an elongated insertion section which is inserted into a living body through a therapeutic device channel of an endoscope, a tubular puncture needle which is disposed at a distal end portion of the insertion section and is made to pierce a living body tissue, a syringe for sampling the living body tissue in a state in which the puncture needle pierces the living body tissue, and a freezing device for subjecting the living body tissue, which is collected by the syringe, to a process for analysis.

Abstract: A display method of measurement information of a biologically relevant material according to the invention displays measurement information on a computer screen when measuring the amount of a biologically relevant material of a test sample or the amount ratio of a biologically relevant material among a plurality of test samples with a microarray.

Abstract: The present invention relates to a gene examining apparatus utilizing a computer, the apparatus comprising (1) DNA microarrays in each of which a large number of fine liquid accommodating sections are two-dimensionally arranged so that openings of the fine liquid accommodating sections are located on the same plane, in which each of the liquid accommodating sections can three-dimensionally accommodate a liquid, and in which hybridization reaction occurs in the liquid accommodating section between a target nucleic acid already labeled with an optical marker substance and the nucleic acid probe, and (2) a microscope comprising a stage supporting the DNA microarrays set forth in (1), a temperature regulating section that regulates the temperature of each DNA microarray, and imaging means for picking up an image of an optical signal from the DNA microarray.

Abstract: A map information system is provided which includes an electronic pen which reads a dot pattern in a form where map images are shown, to output handwriting information, and a processing unit including an association module which associates the output handwriting information with one of the map images where the handwriting information is written and stores it in a storage unit, a search module which searches for the associated handwriting information and map image using information to specify the map image as a search key, a pattern assignment module which when acquiring print request information including information to specify the map images to be printed, newly assigns a dot pattern, and an output instruction module which issues an output instruction so as to cause an output unit to visually output data including the retrieved associated handwriting information and map image and the newly assigned dot pattern.

Abstract: An object of the invention is to provide a quick, easy, and highly-sensitive method of detecting a substance to be analyzed, and to provide a method of supporting the analysis results by quantitativeness even if the amount of samples to be handled is a very small amount. The invention is a method of detecting a substance to be analyzed, including: measuring a intensity of a signal derived from a labeled substance to be analyzed, in a time series during an increase in the signal intensity; and representing the signal intensity by a function of time, and using the quantitative value of the signal intensity for when the slope of an approximated line of the measured signal intensity is within a range between 0.5 and 1.5 times the slope of the approximated line of the previously measured signal intensity.

Abstract: That invention provides a nucleic acid information detection method which, in a method wherein a target nucleic acid, and probes having a complementary sequence with at least a portion of the target nucleic acid sequence, are contacted with each other in order to form hybrids between the target nucleic acid and the probes, and the amount of signal generated depending on the amount of hybrids is measured in order to detect the information on the target nucleic acid, includes kinetically obtaining data of the signal.

Abstract: The present invention relates to a gene examining apparatus utilizing a computer, the apparatus comprising (1) DNA microarrays in each of which a large number of fine liquid accommodating sections are two-dimensionally arranged so that openings of the fine liquid accommodating sections are located on the same plane, in which each of the liquid accommodating sections can three-dimensionally accommodate a liquid, and in which hybridization reaction occurs in the liquid accommodating section between a target nucleic acid already labeled with an optical marker substance and the nucleic acid probe, and (2) a microscope comprising a stage supporting the DNA microarrays set forth in (1), a temperature regulating section that regulates the temperature of each DNA microarray, and imaging means for picking up an image of an optical signal from the DNA microarray.

Abstract: A fluorescence analysis apparatus for analyzing behaviors of fluorescent molecules includes a laser light source, a sample stage that supports a substrate on which a sample including fluorescent molecules is placed, an optical system that converges a light beam from the laser light source on the sample, thus forming a confocal region, a scanning mechanism that moves the confocal region by scanning over the sample, an optical system that converges fluorescence from the sample, a photodetector that detects the converged fluorescence, and fluorescence intensity recording means for recording a change in fluorescence intensity of the fluorescence detected by the photodetector.

Abstract: A method of detecting presence/absence of binding capacity of a test substance, with respect to a protein, comprising, (1) having a protein, which has been labeled with a fluorescence material, exist in a solution, and (2) while successively measuring fluorescence intensity from the fluorescent material, reacting the test substance with the fluorescence-labeled protein described in (1) above and determining presence/absence of binding capacity of the test substance, with respect to the protein, on the basis of the successive change in fluorescence intensity.

Abstract: A method for testing a substance interacting with a hormone receptor, which comprises (a) maintaining a hormone receptor protein labeled with a marker capable of emitting an optical signal and a test substance, under predetermined conditions where a natural ligand can be bound to the receptor protein and where the receptor protein bound the natural ligand causes a change in its state, thereby inducing a change in a detectable characteristic of the optical signal emitted from the marker, (b) detecting the optical signal emitted form the marker under the predetermined conditions, and (c) comparing the characteristic of the optical signal detected in the step (b) with that of the optical signal detected from the marker in the absence of the test substance, thereby determining whether or not the test substance is a substance interacting with the hormone receptor protein on the basis of the difference in both characteristics detected.