Patents by Inventor Hiroko Segawa

Hiroko Segawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel type II Na/Pi cotransporters and type II Na/Pi cotransporter expression regulatory factors
    Publication number: 20070072236
    Abstract: The present invention provides novel type IIc Na/Pi cotransporters. These cotransporters are important Pi transporters that are highly expressed during the growth period from the weaning stage to the adult stage. Furthermore, the present invention provides FGF23 and mutants thereof as factors that regulate the expression of type II Na/Pi cotransporters. FGF23 suppresses Pi reabsorption through suppression of type II Na/Pi cotransporter expression in kidneys. Therefore, FGF23 can be used as a target substance for regulating Pi reabsorption in kidneys. The present invention provides important factors for the development of preventive and therapeutic agents for hyperphosphatemia or hypophosphatemia.
    Type: Application
    Filed: August 22, 2006
    Publication date: March 29, 2007
    Inventors: Keni-Ichi Miyamoto, Hiroko Segawa
  • Novel type II Na/Pi cotransporters and type II Na/Pi cotransporter expression regulatory factors
    Publication number: 20050004348
    Abstract: The present invention provides novel type IIc Na/Pi cotransporters. These cotransporters are important Pi transporters that are highly expressed during the growth period from the weaning stage to the adult stage. Furthermore, the present invention provides FGF23 and mutants thereof as factors that regulate the expression of type II Na/Pi cotransporters. FGF23 suppresses Pi reabsorption through suppression of type II Na/Pi cotransporter expression in kidneys. Therefore, FGF23 can be used as a target substance for regulating Pi reabsorption in kidneys. The present invention provides important factors for the development of preventive and therapeutic agents for hyperphosphatemia or hypophosphatemia.
    Type: Application
    Filed: December 23, 2003
    Publication date: January 6, 2005
    Inventors: Ken-ichi Miyamoto, Hiroko Segawa