Abstract: Provided is a cosmetic product which can generate a carbon dioxide gas to cause foaming by a simple method and having excellent usability. Provided is a cosmetic product comprising a first composition and a second composition different from the first composition as constituent elements of the cosmetic product and which foams by mixing the first composition and the second composition, wherein the first composition is a liquid or creamy composition containing a bicarbonate and/or a carbonate, and the second composition is a liquid or creamy composition containing an ?-hydroxy acid and/or a saturated dibasic acid in which the content of water is 1.0-fold or less in terms of weight ratio with respect to the ?-hydroxy acid and/or the saturated dibasic acid.

Abstract: The present invention concerns a kit of parts comprising a cooking bag for storing food to be cooked in a microwave oven, the cooking bag having a cooking bag opening, and a pressure release closure device, configured for restricting the cooking bag opening when attaching the pressure release closure device at the exterior of the cooking bag thereby contracting the cooking bag opening so as to establish a steam conduit whereby gas pressure in the cooking bag may be released from the cooking bag during cooking in a microwave oven. Further the present invention relates to a pressure release closure device and a method of preparing food using a pressure release closure device.

Abstract: The present invention relates to a polypeptide having 25-hydroxyvitamin D3-1&agr;-hydroxylase activity, being useful for the prevention, diagnosis and therapeutic treatment of adult diseases such as osteoporosis induced by the decrease of active type vitamin D3 and catalyzing the final stage of vitamin D3 activation; and the gene encoding the polypeptide.

Abstract: The present invention relates to a polypeptide having 25-hydroxyvitamin D3-1&agr;-hydroxylase activity, being useful for the prevention, diagnosis and therapeutic treatment of adult diseases such as osteoporosis induced by the decrease of active type vitamin D3 and catalyzing the final stage of vitamin D3 activation; and the gene encoding the polypeptide. In accordance with the present invention, the following can be provided; a polypeptide having 25-hydroxyvitamin D3-1&agr;-hydroxylase activity, DNA encoding the polypeptide, a recombinant DNA prepared by inserting the DNA in a vector, a transformant carrying the recombinant DNA, a method for preparing 25-hydroxyvitamin D3-1&agr;-hydroxylase by using the transformant, a method for preparing 1&agr;, 25-dihydroxyvitamin D3 comprising using the polypeptide having 25-hydroxyvitamin D3-1&agr;-hydroxylase activity, and an antibody recognizing the polypeptide.