Patents by Inventor Hiroko Tsukui

Hiroko Tsukui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8058064
    Abstract: An object of the present invention is to provide a sac-like structure enclosing hematopoietic progenitor cells and a method for preparing the sac-like structure as well as a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the sac-like structure. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, the sac-like structure being obtained by plating ES cells onto feeder cells and culturing the ES cells under suitable conditions for inducing hematopoietic progenitor cell differentiation. Moreover, the present invention provides a method for producing various blood cells, the method comprising further culturing hematopoietic progenitor cells enclosed in the sac-like structure under suitable conditions for inducing blood cell differentiation.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: November 15, 2011
    Assignee: The University of Tokyo
    Inventors: Hiromitsu Nakauchi, Koji Eto, Naoya Takayama, Hidekazu Nishiki-i, Hiroko Tsukui
  • Publication number: 20100197016
    Abstract: An object of the present invention is to provide a sac-like structure enclosing hematopoietic progenitor cells and a method for preparing the sac-like structure as well as a method for efficiently preparing blood cells such as mature megakaryocytes and platelets from the sac-like structure. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, the sac-like structure being obtained by plating ES cells onto feeder cells and culturing the ES cells under suitable conditions for inducing hematopoietic progenitor cell differentiation. Moreover, the present invention provides a method for producing various blood cells, the method comprising further culturing hematopoietic progenitor cells enclosed in the sac-like structure under suitable conditions for inducing blood cell differentiation.
    Type: Application
    Filed: October 4, 2007
    Publication date: August 5, 2010
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Hiromitsu Nakauchi, Koji Eto, Naoya Takayama, Hidekazu Nishiki-i, Hiroko Tsukui