Patents by Inventor Hiroko Usami

Hiroko Usami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor necrosis factor inducing substance derived from acid-fast bacteria
    Patent number: 4900724
    Abstract: The present invention provides a novel amphipathic substance having tumor necrosis factor (TNF) inducing activity. This substance is an amphipathic substance obtained by extraction from several kinds of acid-fast bacteria, and has excellent TNF inducing activity. The toxicity of the substance is much lower than that of the conventional amphipathic substances having TNF inducing activity.
    Type: Grant
    Filed: November 3, 1986
    Date of Patent: February 13, 1990
    Assignees: Sawai Pharmaceutical Co., Ltd, Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yoshiko Kato, Hiroko Usami
  • Antitumor agent
    Patent number: 4678773
    Abstract: An antitumor agent of the present invention comprises, as an effective ingredient, lipoteichoic acid which is extracted from gram-positive bacterial cells.
    Type: Grant
    Filed: August 16, 1984
    Date of Patent: July 7, 1987
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroko Usami, Akihiro Yamamoto, Yutaka Sugawara, Shozo Kotani, Keijiro Kato
  • Anti-tumor substance and process for preparing the same
    Patent number: 4242326
    Abstract: An anti-tumor substance which is not only heatstable but also has low inflaming and pain-inducing properties and low pyrogenic activity is disclosed. The substance is prepared by disrupting cells of bacteria belonging to hemolytic streptococci, extracting from the disrupted material a water-insoluble substance and treating the substance with one or more proteases and, optionally, with one or more nucleases.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: December 30, 1980
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Yutaka Sugawara, Akihiro Yamamoto, Mitsuaki Handa, Hiroko Usami, Haruki Ogawa