Patents by Inventor Hiroko Yamakawa

Hiroko Yamakawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medicament
    Patent number: 11033550
    Abstract: An object of the present invention is to provide a medicament for preventing or treating pulmonary hypertension. The present invention provides a medicament for preventing or treating pulmonary hypertension, comprising a compound selected from the group consisting of (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, (5R)-N-[1-ethyl-1-(4-methoxyphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-5-(2-fluorophenyl)-2,7,7-trimethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, and the salt thereof.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: June 15, 2021
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Juran Kato, Hiroko Yamakawa, You Muraki, Gattu Mahanandeeshwar, Oruganty Satyalakshmi
  • MEDICAMENT
    Publication number: 20200306249
    Abstract: An object of the present invention is to provide a medicament for preventing or treating pulmonary hypertension. The present invention provides a medicament for preventing or treating pulmonary hypertension, comprising a compound selected from the group consisting of (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, (5R)-N-[1-ethyl-1-(4-methoxyphenyl)propyl]-2,7,7-trimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, (5R)-N-[1-ethyl-1-(4-ethylphenyl)propyl]-5-(2-fluorophenyl)-2,7,7-trimethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, and the salt thereof.
    Type: Application
    Filed: March 27, 2017
    Publication date: October 1, 2020
    Inventors: Juran KATO, Hiroko YAMAKAWA, You MURAKI, Gattu MAHANANDEESHWAR, Oruganty SATYALAKSHMI
  • Novel Method of Treating Hyperlipidemia
    Publication number: 20090209510
    Abstract: A pharmaceutical composition useful for a prevention and/or treatment of hyperlipidemia, which comprises combining an effective amount of squalene synthase inhibitor and HMG-CoA reductase inhibitor is provided.
    Type: Application
    Filed: May 31, 2006
    Publication date: August 20, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Tomoyuki Nishimoto, Ryuichi Tozawa, Takeo Wada, Eiichiro Ishikawa, Toshiya Nishi, Hiroko Yamakawa