Patents by Inventor Hiromi MORISHITA

Hiromi MORISHITA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNITY-INDUCING AGENT AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20240075132
    Abstract: Disclosed is an immunity-inducing agent having excellent ease of production and high immunostimulatory activity, the immunity-inducing agent comprising, as an active component, a polynucleotide/peptide conjugate in which an antigenic peptide is covalently bound to a single-stranded polynucleotide or polynucleotide derivative. Also disclosed is a pharmaceutical composition comprising said immunity-inducing agent.
    Type: Application
    Filed: September 8, 2023
    Publication date: March 7, 2024
    Applicant: The University of Kitakyushu
    Inventors: Shinichi Mochizuki, Kazuo Sakurai, Hiromi Morishita
  • Immunity-inducing agent and pharmaceutical composition containing same
    Patent number: 11793874
    Abstract: Disclosed is an immunity-inducing agent having excellent ease of production and high immunostimulatory activity, the immunity-inducing agent comprising, as an active component, a polynucleotide/peptide conjugate in which an antigenic peptide is covalently bound to a single-stranded polynucleotide or polynucleotide derivative. Also disclosed is a pharmaceutical composition comprising said immunity-inducing agent.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: October 24, 2023
    Assignee: The University of Kitakyushu
    Inventors: Shinichi Mochizuki, Kazuo Sakurai, Hiromi Morishita
  • IMMUNITY-INDUCING AGENT AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20210106678
    Abstract: Disclosed is an immunity-inducing agent having excellent ease of production and high immunostimulatory activity, the immunity-inducing agent comprising, as an active component, a polynucleotide/peptide conjugate in which an antigenic peptide is covalently bound to a single-stranded polynucleotide or polynucleotide derivative. Also disclosed is a pharmaceutical composition comprising said immunity-inducing agent.
    Type: Application
    Filed: March 20, 2018
    Publication date: April 15, 2021
    Applicant: The University of Kitakyushu
    Inventors: Shinichi Mochizuki, Kazuo Sakurai, Hiromi Morishita
  • Peptide/?-1,3-glucan complex and production method thereof and pharmaceutical composition containing peptide/?-1,3-glucan complex
    Patent number: 10195270
    Abstract: This peptide/?-1,3-glucan complex includes ?-1,3-glucan and a peptide/polynucleotide conjugate in which an antigenic peptide is bonded covalently to a polynucleotide or a derivative thereof. The polynucleotide or derivative thereof of the peptide/polynucleotide conjugate bonds via a hydrogen bond with ?-1,3-glucan, forming a complex having a triple helix structure including a single molecular chain of the polynucleotide or derivative thereof and two molecular chains of the ?-1,3-glucan. Alternatively, the side chain of the ?-1,3-glucan and the antigenic peptide are bonded covalently formed by either a cycloaddition reaction between an alkyne and an azide derivative, or a reaction between a maleimide group or a vinyl sulfone group and a thiol group.
    Type: Grant
    Filed: December 25, 2014
    Date of Patent: February 5, 2019
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Kazuo Sakurai, Shin-ichi Mochizuki, Hiromi Morishita
  • PEPTIDE/Beta-1,3-GLUCAN COMPLEX AND PRODUCTION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING PEPTIDE/Beta-1,3-GLUCAN COMPLEX
    Publication number: 20170007695
    Abstract: This peptide/?-1,3-glucan complex includes ?-1,3-glucan and a peptide/polynucleotide conjugate in which an antigenic peptide is bonded covalently to a polynucleotide or a derivative thereof. The polynucleotide or derivative thereof of the peptide/polynucleotide conjugate bonds via a hydrogen bond with ?-1,3-glucan, forming a complex having a triple helix structure including a single molecular chain of the polynucleotide or derivative thereof and two molecular chains of the ?-1,3-glucan. Alternatively, the side chain of the ?-1,3-glucan and the antigenic peptide are bonded covalently formed by either a cycloaddition reaction between an alkyne and an azide derivative, or a reaction between a maleimide group or a vinyl sulfone group and a thiol group.
    Type: Application
    Filed: December 25, 2014
    Publication date: January 12, 2017
    Applicant: Japan Science and Technology Agency
    Inventors: Kazuo SAKURAI, Shin-ichi MOCHIZUKI, Hiromi MORISHITA