Abstract: This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3? end.

Abstract: The present invention provides a pancreatic islet isolation method comprising the steps of (1) injecting a protection solution containing a protease inhibitor into the pancreatic duct of an procured pancreas; (3) digesting the pancreas into which the protection solution has been injected; and (4) purifying the digested pancreatic tissue using a purification solution containing a density gradient reagent. The present invention also provides a protection solution for injection into the pancreatic duct, a pancreas preservation solution for the two-layer method, and an islet purification solution.

Abstract: This invention provides a novel RNAi molecule that can significantly potentiate antitumor effects of a 5-FU antitumor agent. The RNAi molecule comprises the nucleotide sequence shown in SEQ ID NO: 2. The invention also provides an antitumor agent comprising such RNAi molecule and a 5-FU antitumor agent.

Abstract: The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.

Abstract: The present invention provides a pancreatic islet isolation method comprising the steps of (1) injecting a protection solution containing a protease inhibitor into the pancreatic duct of an procured pancreas; (3) digesting the pancreas into which the protection solution has been injected; and (4) purifying the digested pancreatic tissue using a purification solution containing a density gradient reagent. The present invention also provides a protection solution for injection into the pancreatic duct, a pancreas preservation solution for the two-layer method, and an islet purification solution.

Abstract: A partner node and a method of communication control with a mobile node that is a communication partner with the partner mode is provided. The mobile node can provide a migration destination address, via a migration post massage transmitted from the mobile node, that can be acquired by an address acquiring unit at the partner node. A packet convert unit can, before the address acquire unit acquires a new migration destination address, generate a packet destined for a pre-migration address of the mobile node. After the address acquire unit acquires a migration destination address, the packet convert unit can generate a final packet configuration destined for the obtained migration destination address. Accordingly, a continuous communication between the corresponding partner node and the mobile node is maintained as the mobile node migrates across networks.

Abstract: A terminal-side communications control unit makes a request to a server for retrieving an instruction file that describes an instruction for transmitting transmission data. The server transmits the instruction file in response to the request for retrieving the instruction file. On receiving the instruction file, the terminal-side communications control unit causes an application executing unit to execute an application, and also forwards the instruction file to a transmission data generating unit. On receiving the instruction file, the transmission data generating part refers to the instruction file to generate, from generated data stored in a generated data storage unit, transmission data to be transmitted to the server.

Abstract: In a content retrieval device, a browser section generates a retrieval request for sub-content data to be retrieved presently. A protocol control section determines which communication path between a first communication path or a second communication path should be used prior to the reception of the sub-content data which is specified by the browser section. If the protocol control section determines that the first communication path is to be used, a first communication control section receives the sub-content data which is specified by the browser section from a content server. If the protocol control section determines that the second communication path is to be used, a second communication control section receives the sub-content data from the content server. In this way, the content retrieval device can select a suitable connection method prior to the reception of data.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: The present invention provides an improved method for treating lung cancer, preferably non-small cell lung cancer, by orally administering UFT to postoperative lung cancer patients.

Abstract: A partner node migration control unit that permits a communication control device, for example of the type carried by a user, to efficiently move across a network, whereby a mobile node can obtain an address assigned to each network and a partner node, which is a communication partner of the mobile node. The migration communication control device, including an address post message receiving unit receiving an address post message indicating the update address of the mobile node from a packet transfer migration control unit. In turn, the packet transfer migration control unit can transmit an updated address of the mobile node to the partner node. A packet conversion unit converts a destination address of the packet to be transmitted to the mobile node into an update address, indicated by the address post message.

Abstract: A cardioplegic solution which contains a trehalose and one or more metal ions. The trehalose is preferably contained in an amount of not more than 3.5% (W/V), or 1.5 to 3.5% (W/V). The metal ions are preferably Na+, K+, Mg++ and Ca++. The cardioplegic solution is useful for cardiac standstill and cardiac muscle protection.

Abstract: A mobile node is provided having an address-obtaining unit that can obtain a temporary address that is assigned to the mobile node for each network to which the mobile node migrates. The temporary address is held an address hold unit and corresponds with a home address that has been set in advance. Additionally, an address post processing unit can post an address post message including the temporary address to a home migration host position control unit that manages addresses of the mobile node.

Abstract: Disclosed is a migration communication control device constructed to control a continuous communication between a mobile node and a node unaffected the mobile node's migration. The migration communication control device comprises a first migration control unit, a second migration control unit on the mobile node, and a third migration control unit on the partner node. The first migration control unit comprises a packet transfer unit and an address post unit. The packet transfer unit receives a packet which was destined for an outdated address of the mobile node, generates a conversion packet which holds an updated address instead of the outdated address, and then transmits the conversion packet, while an address post unit transmits an address post message which indicates the updated address to the third migration control unit. The second migration control unit comprises a migration post unit and a packet resumption unit.

Abstract: A home migration host position control device includes an address post processing unit that is capable of receiving an address post message from the mobile node when it migrates to a different network and is assigned a new temporary address. A home migration host list hold unit can store address information that correlates the temporary address with a home address that is contained in the address post message. A packet transfer unit that can, upon receiving a packet that is destined for the home address of the mobile node, transfer a capsulated packet that is generated by attaching to the received packet a header that indicates a destination address by a temporary address that is correlated with a home address according to address information that is stored in the home migration host list hold unit.