Patents by Inventor Hiromichi Yamashita
Hiromichi Yamashita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11951810Abstract: Provided is a windshield including a glass body with a rectangular shape including a peripheral edge that includes a first side and a second side and a third side that meet the first side; and a heating element disposed at or near the peripheral edge of the glass body, the heating element heating the glass body for deicing. The glass body includes a first region extending along the first side, a second region located along the first side adjacent to the first region, and a third region located along the first side adjacent to the second region on an opposite side to the first region. The heating element is disposed at least in the first region and the second region, heats the first region to higher temperatures than the second region, and heats the second region to higher temperatures than the third region.Type: GrantFiled: June 3, 2019Date of Patent: April 9, 2024Assignee: NIPPON SHEET GLASS COMPANY, LIMITEDInventor: Hiromichi Yamashita
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Publication number: 20230226098Abstract: Provided are an adhesion preventing agent and an adhesion preventing method using the same. Specifically, provided are an adhesion preventing agent, including at least one anionized nanomaterial selected from the group consisting of anionized nanocellulose and anionized nanochitin, and an adhesion preventing method using the adhesion preventing agent.Type: ApplicationFiled: June 1, 2021Publication date: July 20, 2023Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.Inventors: Atsushi OHHATA, Hiromichi YAMASHITA, Shiori FUJIMOTO
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Patent number: 11644448Abstract: A chromatography-mass spectrometry method and apparatus of the present invention includes adding, to a sample, an internal standard material having a retention time similar to that of a target analyte and having a mass-to-charge ratio different from that of the target analyte; measuring the sample with a chromatograph-mass spectrometer and obtaining a chromatogram 101 of the target analyte and a chromatogram 102 of the internal standard material; detecting a peak 113 from the chromatogram of the internal standard material and obtaining a peak start time and a peak end time of the peak; and applying the obtained peak start time and peak end time to a peak start time and a peak end time of the chromatogram of the target analyte.Type: GrantFiled: June 12, 2017Date of Patent: May 9, 2023Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Akira Maekawa, Shinya Ito, Hiromichi Yamashita
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Patent number: 11262337Abstract: Provided is a chromatography mass spectrometry capable of peak detection that can deal with a wide concentration range of a sample component and providing an evaluated value for the result. A plurality of samples having different known concentrations of a component are measured to detect a start point, an apex, and an end point of a peak. Regarding the start point, the apex, and the end point of the detected peak, an evaluated value such as probability is provided as a score to determine a score function. A component having an unknown concentration is measured to detect a start point, an apex, and an end point of a peak. Regarding the start point, the apex, and the end point of the detected peak, the score function is applied to evaluate peak detection results, and a result having a high evaluated value is selected as a peak.Type: GrantFiled: March 5, 2019Date of Patent: March 1, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventor: Hiromichi Yamashita
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Publication number: 20210155082Abstract: Provided is a windshield including a glass body with a rectangular shape including a peripheral edge that includes a first side and a second side and a third side that meet the first side; and a heating element disposed at or near the peripheral edge of the glass body, the heating element heating the glass body for deicing. The glass body includes a first region extending along the first side, a second region located along the first side adjacent to the first region, and a third region located along the first side adjacent to the second region on an opposite side to the first region. The heating element is disposed at least in the first region and the second region, heats the first region to higher temperatures than the second region, and heats the second region to higher temperatures than the third region.Type: ApplicationFiled: June 3, 2019Publication date: May 27, 2021Applicant: NIPPON SHEET GLASS COMPANY, LIMITEDInventor: Hiromichi YAMASHITA
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Publication number: 20210048417Abstract: Provided is a chromatography mass spectrometry capable of peak detection that can deal with a wide concentration range of a sample component and providing an evaluated value for the result. A plurality of samples having different known concentrations of a component are measured to detect a start point, an apex, and an end point of a peak. Regarding the start point, the apex, and the end point of the detected peak, an evaluated value such as probability is provided as a score to determine a score function. A component having an unknown concentration is measured to detect a start point, an apex, and an end point of a peak. Regarding the start point, the apex, and the end point of the detected peak, the score function is applied to evaluate peak detection results, and a result having a high evaluated value is selected as a peak.Type: ApplicationFiled: March 5, 2019Publication date: February 18, 2021Inventor: Hiromichi YAMASHITA
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Publication number: 20200103380Abstract: A chromatography-mass spectrometry method and apparatus of the present invention includes adding, to a sample, an internal standard material having a retention time similar to that of a target analyte and having a mass-to-charge ratio different from that of the target analyte; measuring the sample with a chromatograph-mass spectrometer and obtaining a chromatogram 101 of the target analyte and a chromatogram 102 of the internal standard material; detecting a peak 113 from the chromatogram of the internal standard material and obtaining a peak start time and a peak end time of the peak; and applying the obtained peak start time and peak end time to a peak start time and a peak end time of the chromatogram of the target analyte.Type: ApplicationFiled: June 12, 2017Publication date: April 2, 2020Inventors: Akira MAEKAWA, Shinya ITO, Hiromichi YAMASHITA
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Patent number: 9823228Abstract: A technician is forced to determine the measurement time to be used in a selected ion monitoring (SIM) measurement while observing mass spectral data. Thus, mass spectral data and one or a plurality of mass chromatogram data items is generated on the basis of the detection results of an ion detection unit, and, for each corresponding ion component, the measurement time to be used in SIM is determined on the basis of the elution time range represented by each peak waveform of the one or plurality of mass chromatogram data items that have been generated.Type: GrantFiled: July 29, 2015Date of Patent: November 21, 2017Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Shinji Yoshioka, Hiromichi Yamashita, Akira Maekawa
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Publication number: 20170097328Abstract: A technician is forced to determine the measurement time to be used in a selected ion monitoring (SIM) measurement while observing mass spectral data. Thus, mass spectral data and one or a plurality of mass chromatogram data items is generated on the basis of the detection results of an ion detection unit, and, for each corresponding ion component, the measurement time to be used in SIM is determined on the basis of the elution time range represented by each peak waveform of the one or plurality of mass chromatogram data items that have been generated.Type: ApplicationFiled: July 29, 2015Publication date: April 6, 2017Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Shinji Yoshioka, Hiromichi Yamashita, Akira Maekawa
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Publication number: 20120306883Abstract: The present invention provides a liquid chromatography/mass spectrometry device which enables similarity between an authentic sample and a sample to be compared to be easily recognized on mass spectrum data obtained from each of the authentic sample and the sample to be compared, and also enables each analysis result to be accurately recognized by making unnecessary peaks not to be displayed. For this purpose, the device displays the ionic peak strengths of the mass spectrum data obtained from each of the authentic sample and the sample to be compared, on a map which has a retention time and a mass-to-charge ratio as axes, with the use of light and dark. Furthermore, the device displays only a peak having a designated strength thereon while distinguishing the peak from other peaks, and also provides a map which displays only the peak thereon.Type: ApplicationFiled: October 28, 2010Publication date: December 6, 2012Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Shinji Yoshioka, Hiromichi Yamashita
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Patent number: 7742879Abstract: The results of mass spectrometry are compared; correspondences are established between individual components contained in different samples; the results of establishment of correspondences are checked; and varying components are extracted. At least two samples are compared with respect to the ion intensity corresponding to retention times and mass-to-charge ratios obtained by chromatography-mass spectrometry on the samples having a plurality of components. In ion groups observed as mass spectra, a correspondence between the retention times at which the same component is supposed to be observed is established by determining coincidence between the mass-to-charge ratios and determining that the ion intensity fall within a designated variation.Type: GrantFiled: March 28, 2008Date of Patent: June 22, 2010Assignee: Hitachi High-Technologies CorporationInventor: Hiromichi Yamashita
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Patent number: 7691643Abstract: The invention provides a mass analysis method and apparatus capable of identifying proteins or peptides at greater speed and with improved accuracy. Specifically, a mass analysis method whereby a sample is ionized and a protein is analyzed using a mass analysis apparatus is provided, said method comprising: selecting predetermined information from a database in which information about proteins and peptides is stored, estimating the mass of the selected component, and calculating frequency information for each mass; analyzing a sample using a mass analysis apparatus so as to acquire a mass spectrum, selecting, based on the acquired mass spectrum and said frequency information, a mass to be used for identification, performing mass analysis using the mass spectrum of the selected mass as a precursor ion, and performing an identification process using a resultant mass spectrum.Type: GrantFiled: June 23, 2003Date of Patent: April 6, 2010Assignee: Hitachi High-Technologies CorporationInventors: Hiromichi Yamashita, Yoshiaki Kato
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Patent number: 7485852Abstract: The present invention achieves a mass analysis method that can identify protein or peptide with high speed and high sensitivity. A mass spectrum is obtained from a standard sample of healthy person, an ion is selected from the mass spectrum as a precursor ion, and a mass spectrum of the precursor ion is obtained [(a) to (d)]. A mass spectrum is obtained from a sample of interest to be measured of patient, an ion other than the precursor ion of the standard sample is selected from the mass spectrum as a precursor ion, and a mass spectrum of the precursor ion is obtained [(g) to (k)]. Identifications on peptide/protein specific to the standard sample and the sample to be measured, and common to both are conducted [(r) to (q)], and based on the results, comparative analysis on peptide/protein of the sample to be measured (t).Type: GrantFiled: May 30, 2006Date of Patent: February 3, 2009Assignee: Hitachi High-Technologies CorporationInventors: Hiromichi Yamashita, Akihiro Takeda, Tomoyuki Kurosawa, Kinya Kobayashi
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Publication number: 20080237457Abstract: The results of mass spectrometry are compared; correspondences are established between individual components contained in different samples; the results of establishment of correspondences are checked; and varying components are extracted. At least two samples are compared with respect to the ion intensity corresponding to retention times and mass-to-charge ratios obtained by chromatography-mass spectrometry on the samples having a plurality of components. In ion groups observed as mass spectra, a correspondence between the retention times at which the same component is supposed to be observed is established by determining coincidence between the mass-to-charge ratios and determining that the ion intensity fall within a designated variation.Type: ApplicationFiled: March 28, 2008Publication date: October 2, 2008Inventor: Hiromichi Yamashita
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Patent number: 7211768Abstract: A heating line pattern structure of a defogger comprising a meander shape heating line portion is provided, in which the local temperature rise of a glass panel may be suppressed and which has a good outward appearance. Two lateral heating lines each having a thick width are provided under the meander shape heating line portion. Tow lateral heating lines are connected to each lateral heating line under the meander shape heating line portion through a vertical heating line.Type: GrantFiled: October 19, 2005Date of Patent: May 1, 2007Assignee: Nippon Sheet Glass Company, LimitedInventors: Hiromichi Yamashita, Kazuhisa Ono
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Publication number: 20070059842Abstract: The invention provides a mass analysis method and apparatus capable of identifying proteins or peptides at greater speed and with improved accuracy. Specifically, a mass analysis method whereby a sample is ionized and a protein is analyzed using a mass analysis apparatus is provided, said method comprising: selecting predetermined information from a database in which information about proteins and peptides is stored, estimating the mass of the selected component, and calculating frequency information for each mass; analyzing a sample using a mass analysis apparatus so as to acquire a mass spectrum, selecting, based on the acquired mass spectrum and said frequency information, a mass to be used for identification, performing mass analysis using the mass spectrum of the selected mass as a precursor ion, and performing an identification process using a resultant mass spectrum.Type: ApplicationFiled: June 23, 2003Publication date: March 15, 2007Inventors: Hiromichi Yamashita, Yoshiaki Kato
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Publication number: 20060289736Abstract: The present invention achieves a mass analysis method that can identify protein or peptide with high speed and high sensitivity. A mass spectrum is obtained from a standard sample of healthy person, an ion is selected from the mass spectrum as a precursor ion, and a mass spectrum of the precursor ion is obtained [(a) to (d)]. A mass spectrum is obtained from a sample of interest to be measured of patient, an ion other than the precursor ion of the standard sample is selected from the mass spectrum as a precursor ion, and a mass spectrum of the precursor ion is obtained [(g) to (k)]. Identifications on peptide/protein specific to the standard sample and the sample to be measured, and common to both are conducted [(r) to (q)], and based on the results, comparative analysis on peptide/protein of the sample to be measured (t).Type: ApplicationFiled: May 30, 2006Publication date: December 28, 2006Inventors: Hiromichi Yamashita, Akihiro Takeda, Tomoyuki Kurosawa, Kinya Kobayashi
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Publication number: 20060222720Abstract: An anorectic agent contains an aqueous solvent extract of Vernonia cinerea as an active ingredient, or preferably contains aqueous solvent extracts of Vernonia cinerea and mulberry as active ingredients. The liquid content of the anorectic agent is evaporated so that a dieter can inhale its vapor. The active ingredients are odorless. They are not absorbed into the body through digestive organs if taken orally, but can be taken directly into blood through respiratory organs such as lungs and nose mucous membrane. The active ingredients then acts on the central nervous system, thereby causing the dieter to lose appetite and thus lose weight. This effect does not appear in a person who does not want to lose weight. The dieter can thus lose weight easily, safely and healthily without undue efforts.Type: ApplicationFiled: March 10, 2006Publication date: October 5, 2006Inventor: Hiromichi Yamashita
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Publication number: 20060086714Abstract: A heating line pattern structure of a defogger comprising a meander shape heating line portion is provided, in which the local temperature rise of a glass panel may be suppressed and which has a good outward appearance. Two lateral heating lines each having a thick width are provided under the meander shape heating line portion. Tow lateral heating lines are connected to each lateral heating line under the meander shape heating line portion through a vertical heating line.Type: ApplicationFiled: October 19, 2005Publication date: April 27, 2006Applicant: Nippon Sheet Glass Company, LimitedInventors: Hiromichi Yamashita, Kazuhisa Ono
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Patent number: 6748956Abstract: This invention is directed to a cigarette filter containing an extract of Vernonia Cinerea (L.) Less. According to this invention, novel cigarette filter and cigarette are provided which are capable of effectively providing a desired effect in facilitating smokers' suppressing smoking or giving up smoking such as to satisfy smokers' desire to smoke and smoking habit without changing the cigarette's own flavor thereby allowing the smokers to reduce the number of cigarettes smoked easily while permitting them to keep on smoking without interruption.Type: GrantFiled: May 14, 2002Date of Patent: June 15, 2004Inventor: Hiromichi Yamashita