Abstract: A misfueling preventing apparatus discriminates a fuel filler nozzle based on an outer diameter of the fuel filler nozzle. The misfueling preventing apparatus includes a base, a first link arm, a second link arm, a flapper and a stopper. The first link arm has a first trigger projection. The second link arm has a second trigger projection. If the fuel filler nozzle of light diesel oil pushes the first trigger projection and the second trigger projection, the first link arm and second link arm swing to a direction to which the first link arm and second link arm open to, placing the flapper in an openable state.

Abstract: The present invention provides a pharmaceutical composition which prevents from decreasing the blood exposure of the third generation coxib-drugs, a process for preparing the said pharmaceutical composition and its use. It has been founded in this invention that adding a basic amine or a basic amino acid, or a cyclodextrin to the third generation coxib-drug can afford a pharmaceutical composition which can prevent from decreasing the blood exposure, AUC and bioavailability. The pharmaceutical composition of the present invention has also good stability, which is useful for drugs. Namely, the technological thought that adding a basic amine or a basic amino acid, or a cyclodextrin to the third generation coxib-drug can prevent from decreasing the blood exposure, AUC and bioavailability has been established in this invention.

Abstract: Present disclosure is a misfueling preventing apparatus discriminating a fuel filler nozzle based on an outer diameter of the fuel filler nozzle. The misfueling preventing apparatus includes a base, a first link arm, a second link arm, a flapper and the stopper. The first link arm has a first trigger projection. The second link arm has a second trigger projection. If the fuel filler nozzle of light diesel oil pushes the first trigger projection and the second trigger projection, the first link arm and second link arm swing to a direction to which the first link arm and second link arm open to allow the flapper rotates to open.

Abstract: The present invention provides a pharmaceutical composition which prevents from decreasing the blood exposure of the third generation coxib-drugs, a process for preparing the said pharmaceutical composition and its use. It has been founded in this invention that adding a basic amine or a basic amino acid, or a cyclodextrin to the third generation coxib-drug can afford a pharmaceutical composition which can prevent from decreasing the blood exposure, AUC and bioavailability. The pharmaceutical composition of the present invention has also good stability, which is useful for drugs. Namely, the technological thought that adding a basic amine or a basic amino acid, or a cyclodextrin to the third generation coxib-drug can prevent from decreasing the blood exposure, AUC and bioavailability has been established in this invention.

Abstract: A fuel filler port closing apparatus including an opening (44) of a filler neck or an opening (211) of a nozzle guide (21) securely and reliably sealed, even when a seal packing (325) sags, bends or deflects. Sealing is realized by a flapper (3) including a rotation plate (31) which rotates and flaps, and a seal plate (32) having the seal packing (325) moving freely in an up and down direction with respect to the rotation plate (31).

Abstract: Problems to be solved: To provide a fuel filler port closing apparatus that can be adapted to fuel filling nozzles of various shapes and that excels in operability. Means to solve the problems: Problems are solved through the fuel filler port closing apparatus adapting two-action fuel filling operation. The first action is to open a cover 5 closing an opening 44 of a fuel filler port by pushing a slider 53 with fuel filling nozzle 71, and the second action is to push and open a flapper 3 closing an opening 211 of a nozzle guide.

Abstract: This invention provides a fuel filler cap that can release an outer cap from an inner cap without influences of direction of the external force when it applied. The fuel filler cap 1 comprises the outer cap 11 constructed by an upper face portion 112, a skirt portion 113 extending from the outer circumference of the upper face portion 112 and a plurality of wedge-shaped projection 111 formed on the inner face of the skirt portion 113; the pressing plate 15; and the inner cap 13 constructed by a supporting plate 14 having an annular slant 142, a seal ring 12 and annular groove 146 defined by the lower face of the pressing plate 15 laid over the supporting plate 14 and by the annular slant 142.

Abstract: According to a fuel filler port closing apparatus of the present invention, an opening 44 of a filler neck or an opening 211 of a nozzle guide 21 is securely and reliably sealed, even when a seal packing 325 sags, bends or deflects. Such a reliable sealing is realized by a characteristic flapper 3 comprising a rotation plate 31 rotates and flaps, and a seal plate 32 having the seal packing 325 moving freely to up and down direction with respect to the rotation plate 31.

Abstract: Problems to be solved: To provide a fuel filler port closing apparatus that can be adapted to fuel filling nozzles of various shapes and that excels in operability. Means to solve the problems: Problems are solved through the fuel filler port closing apparatus adapting two-action fuel filling operation. The first action is to open a cover 5 closing an opening 44 of a fuel filler port by pushing a slider 53 with fuel filling nozzle 71, and the second action is to push and open a flapper 3 closing an opening 211 of a nozzle guide.

Abstract: This invention provides a fuel filler cap that can release an outer cap from an inner cap without influences of direction of the external force when it applied. The fuel filler cap 1 comprises the outer cap 11 constructed by an upper face portion 112, a skirt portion 113 extending from the outer circumference of the upper face portion 112 and a plurality of wedge-shaped projection 111 formed on the inner face of the skirt portion 113, the pressing plate 15, and the inner cap 13 constructed by a supporting plate 14 having annular slants 142 formed downward by chamfering the peripheral edge of its upper face intermittently, a seal ring 12 and a plurality of annular groove 146 defined by the individual annular slants 142 of the supporting plate 14 and by the lower face of the pressing plate 15 laid over the supporting plate 14.

Abstract: A fuel cap comprising a closure unit adapted to be fitted into an opening of a filler neck having ridges formed on its inner side face intermittently in the circumferential direction, so that it may be secured to the filler neck by engaging with the ridges during a turning operation. The closure unit includes a closure body, a seal ring, a turning control sleeve, a sliding sleeve, a base and a coil spring. The amount of the spacing formed between the lower end of the sliding sleeve and the base is set smaller than an amount of the downward sliding of the sliding sleeve, which is caused when the engagement protrusions formed on the outer side face of the sliding sleeve slip into lower face of the ridges formed on the inner side face of the filler neck.

Abstract: A lower sash made of resin comprising a scraper for suppressing or preventing entry of the foreign substances itself as means for suppressing or preventing generation of noise is provided. The lower sash made of resin comprising a substantially channel-structured frame extending along a direction in which a window glass ascends and descends, the frame comprising wings provided upright on both sides of a base, and glass guides provided in opposition to the wings each other, and further comprising a scraper is provided at an upper end of the frame to come into sliding contact with an outer surface of the descending window glass.

Abstract: The invention provides a shutter-operated fuel filler port closing apparatus in which a countermeasure for static electricity is applied. The shutter-operated fuel filler port closing apparatus includes a dust cover which is capable of tilting for closing up a fuel filler port and a hinged haft for the dust cover which have electrical conductivity, and the hinged shaft and a filler neck are electrically connected by an electrically conductive leaf spring, so that static electricity is discharged from the dust cover to the filler neck through the hinged shaft and the electrically conductive leaf spring. Since the dust cover is opened always with a hand or hands for fueling, the static electricity can be discharged inevitably to the filler neck through actions to open the dust cover, so that spark discharge can be prevented.

Abstract: A fuel cap comprising a seal ring 1 mounted on a cap trunk portion 223 to realize liquid tightness and gas tightness, wherein the seal ring 1 includes a ring body 11 and an elastic support portion; the ring body 11 has a sizing relation between an external diameter Dc of the cap trunk portion 223 and an internal diameter Din of the ring body 11 which is Dc<Din, and has a C-shaped section formed by a wedged circumferential groove opening outward in radial direction of the ring; and the elastic support portion is a plurality of the elastic members 12,13,14,15,16 or one of the elastic flanges 17,18, or combination thereof, and disposed on the inner circumference side of the ring body 11 and protrudes with an amount of a radially inward protrusion d set at (Din?Dc)/2 or greater.

Abstract: The present invention provides a fuel cap having a high operability while maintaining the air-tightness thereof at a necessary and sufficient level. The closure includes a closure body having a head portion, a trunk portion and an annular trunk surface having stopper projections; a seal ring; a sleeve; a coiled spring; and an engagement member having engagement projections. The fuel cap is formed by assembling the seal ring around the annular surface of the trunk portion of the closure body and the sleeve with the trunk portion in the mentioned order, interposing the coiled spring between the sleeve and engagement member, and connecting the engagement member to the trunk portion of the closure body.

Abstract: An aerosol preparation comprising an enclosure enclosing an aerosol composition containing a macrolide compound (e.g., tacrolimus) serving as an active ingredient has a problem such that the formulation of the aerosol composition is changed with the passage of time so as to reduce the ratio of the active ingredient in the aerosol composition because the macrolide compound as the active ingredient is partly adsorbed to a “gasket” of a valve part made of resinous material. In an aerosol preparation of the invention comprising an aerosol composition containing a macrolide compound and an enclosure enclosing the aerosol composition, a valve part of the enclosure has a “gasket” made of at least one resinous material selected from butyl rubber, ethylene-propylene rubber, chloroprene rubber, polyethylene, polybutylene terephthalate, polyacetal, polyamide, polytetrafluoroethylene, polypropylene and thermoplastic elastomer, thereby solving the problem.

Abstract: This invention provides a fuel filler cap that can release an outer cap from an inner cap without influences of direction of the external force when it applied. The fuel filler cap 1 comprises the outer cap 11 constructed by an upper face portion 112, a skirt portion 113 extending from the outer circumference of the upper face portion 112 and a plurality of wedge-shaped projection 111 formed on the inner face of the skirt portion 113, the pressing plate 15, and the inner cap 13 constructed by a supporting plate 14 having annular slants 142 formed downward by chamfering the peripheral edge of its upper face intermittently, a seal ring 12 and a plurality of annular groove 146 defined by the individual annular slants 142 of the supporting plate 14 and by the lower face of the pressing plate 15 laid over the supporting plate 14.

Abstract: This invention provides a fuel filler cap that can release an outer cap from an inner cap without influences of direction of the external force when it applied. The fuel filler cap 1 comprises the outer cap 11 constructed by an upper face portion 112, a skirt portion 113 extending from the outer circumference of the upper face portion 112 and a plurality of wedge-shaped projection 111 formed on the inner face of the skirt portion 113; the pressing plate 15; and the inner cap 13 constructed by a supporting plate 14 having an annular slant 142, a seal ring 12 and annular groove 146 defined by the lower face of the pressing plate 15 laid over the supporting plate 14 and by the annular slant 142.

Abstract: A fuel cap comprising a closure unit adapted to be fitted into an opening of a filler neck having ridges formed on its inner side face intermittently in the circumferential direction, so that it may be secured to the filler neck by engaging with the ridges in turning operation. The closure unit includes a closure body, a seal ring, a turning control sleeve, a sliding sleeve, a base and a coil spring. An amount of the spacing formed between the lower end of the sliding sleeve and the base is set smaller than an amount of the downward sliding of the sliding sleeve, which is caused when the engagement protrusions formed on the outer side face of the sliding sleeve slip into lower face of the ridges formed on the inner side face of the filler neck.

Abstract: A lower sash made of resin comprising a scraper for suppressing or preventing entry of the foreign substances itself as means for suppressing or preventing generation of noise is provided. The lower sash made of resin comprising a substantially channel-structured frame extending along a direction in which a window glass ascends and descends, the frame comprising wings provided upright on both sides of a base, and glass guides provided in opposition to the wings each other, and further comprising a scraper is provided at an upper end of the frame to come into sliding contact with an outer surface of the descending window glass.