Patents by Inventor Hiromu Murofushi

Hiromu Murofushi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carba cyclic phosphatidic acid derivative
    Patent number: 7550449
    Abstract: It is an object of the present invention to synthesize a carba cyclic phosphatidic acid derivative having a novel structure by substituting O at position sn-2 of the glycerol skeleton with CH2, and study the action of the obtained derivative to suppress cancer cell invasion. The present invention provides a compound represented by the following formula (I): wherein R represents a linear or branched alkyl group containing 1 to 30 carbon atoms, a linear or branched alkenyl group containing 2 to 30 carbon atoms, or a linear or branched alkynyl group containing 2 to 30 carbon atoms, wherein these groups may comprise a cycloalkane ring or aromatic ring; and M represents a hydrogen atom or counter cation.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: June 23, 2009
    Inventors: Kimiko Murofushi, Mutsuko Mukai, Susumu Kobayashi, Hiromu Murofushi
  • Carbacyclic phosphatidic acid derivative
    Publication number: 20060122155
    Abstract: It is an object of the present invention to synthesize a carba cyclic phosphatidic acid derivative having a novel structure by substituting O at position sn-2 of the glycerol skeleton with CH2, and study the action of the obtained derivative to suppress cancer cell invasion. The present invention provides a compound represented by the following formula (I): wherein R represents a linear or branched alkyl group containing 1 to 30 carbon atoms, a linear or branched alkenyl group containing 2 to 30 carbon atoms, or a linear or branched alkynyl group containing 2 to 30 carbon atoms, wherein these groups may comprise a cycloalkane ring or aromatic ring; and M represents a hydrogen atom or counter cation.
    Type: Application
    Filed: June 10, 2003
    Publication date: June 8, 2006
    Inventors: Kimiko Murofushi, Mutsuko Mukai, Susumu Kabayashi, Hiromu Murofushi
  • Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives
    Publication number: 20040214799
    Abstract: An object of the present invention is to provide a novel agent for suppression of cancer metastasis by studying the suppressing action of cancer cell invasion by carbacyclic phosphatidic acid derivatives.
    Type: Application
    Filed: June 1, 2004
    Publication date: October 28, 2004
    Inventors: Mutsuko Mukai, Susumu Kobayashi, Hiromu Murofushi, Kimiko Murofushi