Patents by Inventor Hiromu Ohnogi
Hiromu Ohnogi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20100317613Abstract: It is intended to provide a drug, a food or a feed which has an effect of enhancing the activity of a second-phase detoxifying enzyme and an effect of increasing intracellular glutathione content.Type: ApplicationFiled: October 11, 2007Publication date: December 16, 2010Applicant: TAKARA BIO INC.Inventors: Hiromu Ohnogi, Yoko Kudo, Hiroko Nakahara, Tatsuji Enoki, Ikunoshin Kato
-
Publication number: 20100105867Abstract: A process for producing an extract containing activated osteocalcin; an extract which can be obtained by this production process; a food, a drink, a drug, an oral cavity-care composition and a feed containing this extract; and a growth enhancer containing osteocalcin originating in a bone.Type: ApplicationFiled: March 5, 2008Publication date: April 29, 2010Applicant: TAKARA BIO INC.Inventors: Hiromu Ohnogi, Shinichi Adachi, Kazuo Nakagawa, Hiroki Iwamoto, Ikunoshin Kato
-
Publication number: 20090292012Abstract: A therapeutic agent or prophylactic agent for a disease requiring an anti-foaming action for a cell and/or an inhibitory action for acyl-CoA cholesterol acyltransferase in treatment or prevention, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient a processed product derived from Peucedanum japonicum.Type: ApplicationFiled: January 26, 2006Publication date: November 26, 2009Inventors: Tatsuji Enoki, Yoko Kudo, Katsumi Sugiyama, Hiromu Ohnogi, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20090076136Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed, an agent for enhancement of glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, each comprising as an effective ingredient at least one compound selected from the group consisting of specified compounds having an insulin-mimetic action, derivatives thereof, and pharmacologically acceptable salts thereof.Type: ApplicationFiled: November 3, 2008Publication date: March 19, 2009Inventors: Tatsuji ENOKI, Eiji Kobayashi, Kinuko Ogawa, Yoko Kudo, Masashige Tanabe, Hiromu Ohnogi, Hiroaki Sagawa, Ikunoshin Kato
-
Patent number: 7498357Abstract: The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a therapeutic or prophylactic effect for a disease showing sensitivity to the compound, by utilizing the physiological actions of the compound.Type: GrantFiled: December 1, 2004Date of Patent: March 3, 2009Assignee: Takara Bio Inc.Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Tatsuji Enoki, Eiji Kobayashi, Hiroaki Sagawa, Ikunoshin Kato
-
Patent number: 7361774Abstract: The present invention relates to a chalcone compound represented by the following general formula: wherein R1 and R2 are taken together with the carbon atom to which they are bound, respectively, to form a hydroxydimethyl hexane ring, or where R1 is a hydroxyl group, R2 is an isohexenyl group, a derivative thereof, or a salt thereof. Also, the present invention relates to a therapeutic agent or prophylactic agent for a disease requiring neuronal protection, suppression for nitrogen monoxide (NO) production, inhibition for aldose reductase or suppression for interleukin production, and a food, beverage or feed for treatment or prevention of the above-mentioned disease, characterized in that each comprises the above-mentioned compound as an effective ingredient.Type: GrantFiled: September 29, 2003Date of Patent: April 22, 2008Assignee: Takara Bio Inc.Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Tatsuji Enoki, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20080044498Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed for treating or preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancement of glucose uptake into a cell, and an agent for induction of an adipocyte differentiation, each comprising as an effective ingredient a processed product derived from a plant belonging to Umbelliferae.Type: ApplicationFiled: October 5, 2007Publication date: February 21, 2008Inventors: Tatsuji Enoki, Kinuko Ogawa, Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20080008773Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring promotion of osteogenesis or enhancement of bone morphogenetic protein production, an agent for promotion of osteogenesis or an agent for enhancement of bone morphogenetic protein production, and a food, beverage or feed for promotion of osteogenesis or enhancement of bone morphogenetic protein production, characterized in that each comprises as an effective ingredient a processed product derived from a plant. Also, the present invention relates to a method for measuring an enhancing action for bone morphogenetic protein production, a method for screening a substance having an enhancing action for bone morphogenetic protein production, and a method for preparing a substance having an enhancing action for bone morphogenetic protein production, each method using a specified cell.Type: ApplicationFiled: June 27, 2007Publication date: January 10, 2008Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Hiroaki Sagawa, Ikunoshin Kato
-
Patent number: 7268160Abstract: The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production, each comprising as an effective ingredient a specified compound or a salt thereof having enhancing activity for nerve growth factor production; a method for enhancing nerve growth factor production, comprising administering to a mammal the above-mentioned compound or a salt thereof; and use of the above-mentioned compound or a salt thereof in the preparation of a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production. In addition, the present invention provides novel compounds having enhancing activity for nerve growth factor production.Type: GrantFiled: January 26, 2001Date of Patent: September 11, 2007Assignee: Takara Bio, Inc.Inventors: Hiromu Ohnogi, Masahiro Shiraga, Eiji Kobayashi, Tuo-Ping Li, Suzu Deguchi, Eiji Nishiyama, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20070112066Abstract: The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a therapeutic or prophylactic effect for a disease showing sensitivity to the compound, by utilizing the physiological actions of the compound.Type: ApplicationFiled: December 1, 2004Publication date: May 17, 2007Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Tatsuji Enoki, Eiji Kobayashi, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20070092587Abstract: The present invention provides an extract obtainable by extracting a plant belonging to Umbelliferae, or a processed product thereof, with a water-containing alcohol; a process for preparing the extract; a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response and/or diabetic complications, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient the extract as defined above; an agent for an insulin-mimetic action, characterized in that the agent comprises as an effective ingredient the extract as defined above; a food, beverage or feed, comprising the extract as defined above; an agent for enhancing glucose uptake into a cell, characterized in that the agent comprises as an effective ingredient the extract as defined above; to an agent for inducing differentiation into an adipocyte, characterized in that the agent comprises as an effective ingredient the extract as defined above; and an inhibiType: ApplicationFiled: June 18, 2004Publication date: April 26, 2007Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Tatsuji Enoki, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20070092551Abstract: A therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of a chalcone compound, an acetophenone compound, a coumarin compound, a phthalide compound, derivatives thereof, and pharmacologically acceptable salts thereof.Type: ApplicationFiled: April 30, 2004Publication date: April 26, 2007Applicant: TAKARA BIO INC.Inventors: Tatsuji Enoki, Eiji Kobayashi, Kinuko Ogawa, Yoko Kudo, Masashige Tanabe, Hiromu Ohnogi, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20070060641Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed, an agent for enhancement of glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, each comprising as an effective ingredient at least one compound selected from the group consisting of specified compounds having an insulin-mimetic action, derivatives thereof, and pharmacologically acceptable salts thereof.Type: ApplicationFiled: May 18, 2004Publication date: March 15, 2007Inventors: Tatsuji Enoki, Eiji Kobayashi, Kinuko Ogawa, Yoko Kudo, Masashige Tanabe, Hiromu Ohnogi, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060216362Abstract: The present invention relates to a therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed for treating a preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient a processed product derived from at least one plant selected from the group consisting of (a) a plant belonging to Tiliaceae, (b) a plant belonging to Zingiberaceae, (c) a plant belonging to Compositae, (d) a plant belonging to Liliaceae, and (e) a plant belonging to Polygonaceae.Type: ApplicationFiled: May 14, 2004Publication date: September 28, 2006Inventors: Tatsuji Enoki, Kinuko Ogawa, Hiromu Ohnogi, Nobuko Muraki, Yoko Kudo, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060199774Abstract: The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF production, wherein the compound has a coumarin and/or chroman backbone. Since no toxicity is especially found in the effective ingredient of the present invention, and there is no risk of incidence of adverse actions, the treatment or the like of the above disease can be safely and appropriately carried out.Type: ApplicationFiled: April 24, 2006Publication date: September 7, 2006Inventors: Hiromu Ohnogi, Masahiro Shiraga, Hiroaki Sagawa, Ikunoshin Kato
-
Patent number: 7078386Abstract: The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF production, wherein the compound has a coumarin and/or chroman backbone. Since no toxicity is especially found in the effective ingredient of the present invention, and there is no risk of incidence of adverse actions, the treatment or the like of the above disease can be safely and appropriately carried out.Type: GrantFiled: March 28, 2002Date of Patent: July 18, 2006Assignee: Takara Bio, Inc.Inventors: Hiromu Ohnogi, Masahiro Shiraga, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060147558Abstract: The present invention provides a composition for enhancing growth factor production, comprising a plant-derived enhancer for growth factor production; a therapeutic agent or prophylactic agent for a disease requiring enhancement of growth factor production and a food, beverage or feed for enhancing growth factor production, each comprising the above composition. In addition, the present invention relates to a functional food, beverage or feed excellent in health enhancement.Type: ApplicationFiled: October 26, 2005Publication date: July 6, 2006Inventors: Hiromu Ohnogi, Masahiro Shiraga, Tuo-Ping Li, Eiji Kobayashi, Kaori Nishimura, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060051316Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring enhancement of bone morphogenetic protein production or promotion of osteogenesis; an agent for enhancement of bone morphogenetic protein production or an agent for promotion of osteogenesis, a food, beverage or feed for enhancement of bone mornhogenetic protein production or promotion of osteogenesis, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of (a) an acidic saccharide, (b) a polyacrylic acid, (c) chlorogenic acid and (d) an oxidation processed product of chlorogenic acid, or an extract derived from algae.Type: ApplicationFiled: December 5, 2003Publication date: March 9, 2006Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060039998Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring promotion of osteogenesis or enhancement of bone morphogenetic protein production, an agent for promotion of osteogenesis or an agent for enhancement of bone morphogenetic protein production, and a food, beverage or feed for promotion of osteogenesis or enhancement of bone morphogenetic protein production, characterized in that each comprises as an effective ingredient a processed product derived from a plant. Also, the present invention relates to a method for measuring an enhancing action for bone morphogenetic protein production, a method for screening a substance having an enhancing action for bone morphogenetic protein production, and a method for preparing a substance having an enhancing action for bone morphogenetic protein production, each method using a specified cell.Type: ApplicationFiled: September 29, 2003Publication date: February 23, 2006Inventors: Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Hiroaki Sagawa, Ikunoshin Kato
-
Publication number: 20060034949Abstract: The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed for treating or preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancement of glucose uptake into a cell, and an agent for induction of an adipocyte differentiation, each comprising as an effective ingredient a processed product derived from a plant belonging to Umbelliferae.Type: ApplicationFiled: August 6, 2003Publication date: February 16, 2006Inventors: Tatsuji Enoki, Kinuko Ogawa, Hiromu Ohnogi, Katsumi Sugiyama, Nobuko Muraki, Hiroaki Sagawa, Ikunoshin Kato