Abstract: A method is disclosed for purifying an antibody monomer, comprising providing a porous membrane comprising a hydrophobic porous substrate, a hydrophilic molecular chain of a different material from that of the porous substrate, immobilized on the surface of pores of the porous substrate, and a side chain of the molecular chain, containing a nitrogen atom to which one to three alkyl groups each having two or three carbon atoms are bonded; passing an antibody solution containing antibody aggregates of dimers or higher-order multimers through the porous membrane to adsorb the antibody aggregates to the porous membrane; and recovering the purified antibody monomer in the passed solution.

Abstract: It is an object of the present invention to provide a method for eluting an adsorbed protein that suppresses a decrease in protein adsorption ability, in a method for purifying a protein using a protein-adsorbing porous membrane. The present invention provides a method for purifying a protein, comprising an adsorption step and an elution step, wherein in the elution step, at least one eluent is passed in the opposite direction with respect to the direction of the passage of a stock solution containing an adsorption target protein, in the adsorption step.

Abstract: It is an object of the present invention to provide a method for eluting an adsorbed protein that suppresses a decrease in protein adsorption ability, in a method for purifying a protein using a protein-adsorbing porous membrane. The present invention provides a method for purifying a protein, comprising an adsorption step and an elution step, wherein in the elution step, at least one eluent is passed in the opposite direction with respect to the direction of the passage of a stock solution containing an adsorption target protein, in the adsorption step.

Abstract: The present invention provides a method for purifying a protein to remove impurities from a mixture liquid containing a desired protein and the impurities, comprising the step of performing filtration using a porous membrane having a graft chain on a pore surface and an anion-exchange group fixed to the graft chain.

Abstract: The present invention provides a method for purifying a protein to remove impurities from a mixture liquid containing a desired protein and the impurities, comprising performing filtration using a porous membrane having a graft chain on a pore surface and an anion-exchange group fixed to the graft chain.

Abstract: The present invention provides a method for purifying a protein to remove impurities from a mixture liquid containing a desired protein and the impurities, comprising the step of performing filtration using a porous membrane having a graft chain on a pore surface and an anion-exchange group fixed to the graft chain.

Abstract: A heat sensitive type plate material for forming lithography comprising a substrate (1) and, formed thereon, a heat sensitive layer (2), which in turn comprises a hydrophilic polymer (3) having a Lewis base moiety, lipophilic part forming particles (4) which form a lipophilic part on the surface of a plate through the change caused by heat, and polyvalent metal oxide particles (5), the lipophilic part forming particles (4) and the polyvalent metal oxide particles (5) being dispersed homogeneously in the heat sensitive layer (2). The plate material requires no developing process on forming a plate, and can form a lithography which has not only high mechanical strength, but also high printing durability, and further can be prepared with no significant increase of production cost.

Abstract: Disclosed is a coating composition comprising: (A) a silica precursor comprising at least one member selected from the group consisting of alkoxysilanes and hydrolysis/polycondensation products formed by hydrolysis/polycondensation reactions of the alkoxysilanes under acidic conditions, and (B) an organic polymer containing 20% by weight or more, based on the weight of the organic polymer, of an organic block copolymer, wherein the coating composition has an acidic pH value.