Patents by Inventor Hironori Imma

Hironori Imma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiepileptic agent
    Publication number: 20060122198
    Abstract: An antiepileptic agent which contains either a xanthine derivative represented by the formula (I): (I) (wherein R1, R2, and R3 are the same or different and each represents hydrogen, lower alkyl, lower alkenyl, or lower alkynyl; R4 represents cycloalkyl, —(CH2)n.R5, or the formula (II); (II) and X1 and X2 are the same or different and each represents oxygen or sulfur) or a pharmacologically acceptable salt thereof as an active ingredient.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 8, 2006
    Applicant: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Shunji Ichikawa, Chiemi Takashima, Hironori Imma, Junichi Shimada
  • Receptor Antagonists
    Publication number: 20040110826
    Abstract: The present invention provides an &agr;2c-adrenoceptor antagonist comprising, as an active ingredient, a condensed-ring-pyrimidine derivative represented by general formula (I) below or a pharmaceutically acceptable salt thereof useful for treating and/or preventing various diseases induced by hyperactivity of &agr;2c-adrenoceptor (for example, Parkinson's disease, L-DOPA-induced dyskinesia, tardive dyskinesia and depression) and the like.
    Type: Application
    Filed: May 28, 2003
    Publication date: June 10, 2004
    Inventors: Noriaki Uesaka, Hironori Imma, Hajime Kashima, Masako Kurokawa, Hiromi Nonaka, Tomoyuki Kanda, Yoshihisa Kuwana, Shinichiro Toki, Junichi Shimada
  • [1,2,4]triazolo[1,5-c]pyrimidine derivatives
    Patent number: 6545000
    Abstract: The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine compounds represented by formula (I): wherein na and nb independently represent an integer of 0 to 4 and Q represents a hydrogen atom or 3,4-dimethoxybenzyl, or salts thereof exhibit activity as adenosine A2A receptor antagonists.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: April 8, 2003
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Junichi Shimada, Hironori Imma, Naoto Osakada, Shizuo Shiozaki, Tomoyuki Kanda, Yoshihisa Kuwana
  • [1,2,4] triazolo [1,5-C] pyrimidine derivatives
    Patent number: 6222035
    Abstract: [1,2,4]Triazolo[1,5-c]pyrimidine derivatives represented by formula (I) or pharmaceutically acceptable salts thereof are provided, which have adenosine A2A receptor antagonism and are useful for the treatment or prevention of various diseases induced by hyperactivity of adenosine A2A receptors (for example, Parkinson's disease or senile dementia): wherein R1 represents substituted or unsubstituted aryl, or the like; R2 represents hydrogen, halogen, lower alkyl, substituted or unsubstituted aryl, or the like; R3 represents hydrogen, halogen, XR10 (wherein X represents O or S; and R10 represents substituted or unsubstituted aryl, a substituted or unsubstituted aromatic heterocyclic ring, substituted or unsubstituted aralkyl, lower alkyl, or hydroxy lower alkyl), or the like; and Q represents hydrogen or 3,4-dimethoxybenzyl.
    Type: Grant
    Filed: September 23, 1999
    Date of Patent: April 24, 2001
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Hiroshi Tsumuki, Junichi Shimada, Hironori Imma, Akiko Nakamura, Hiromi Nonaka, Shizuo Shiozaki, Shunji Ichikawa, Tomoyuki Kanda, Yoshihisa Kuwana, Michio Ichimura, Fumio Suzuki