Patents by Inventor Hironori Komatsu

Hironori Komatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of trifluorothymidine derivatives
    Patent number: 6423852
    Abstract: 5-trifluoromethyl-2,4-bis(trimethylsilyloxy)pyrimidine is reacted with a 2-deoxy-&agr;-D-erythro-pentofuranosyl chloride derivative reacted in the absence or presence of a small amount of solvent to give a &bgr;-form of 1-(2′-deoxy-&bgr;-D-erythro-pentofuranosyl)-5-trifluoromethyl uracil derivative with a high selectivity.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: July 23, 2002
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hideki Umetani, Nobuyuki Fukazawa, Hironori Komatsu
  • Benzimidazole derivatives
    Patent number: 5852011
    Abstract: Disclosed are compounds represented by the following chemical formula (I) and pharmacologically acceptable salts thereof which are novel compounds useful as anticancer agents, antiviral agents or antimicrobial agents.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: December 22, 1998
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Akio Matsunaga, Yuki Nakajima, Hiroshi Kohno, Hironori Komatsu, Hajime Edatsugi, Daiji Iwata, Kimiko Takezawa
  • Process for production of glycide derivative
    Patent number: 5463061
    Abstract: A glycide derivative represented by the following general formula (I) is produced by reacting a hydroxyaryl or heteroaryl represented by A-OH with glycidyl tosylate in the presence of a cesium base as a base. Thereby, an aryl glycidyl ether derivative, which is an important intermediate for drug production, can be produced easily and reliably. Particularly when optically active glycidyl tosylate is used, said compound can be obtained at a high optical purity. ##STR1## wherein A represents an aryl group or a heteroaryl group.
    Type: Grant
    Filed: January 13, 1994
    Date of Patent: October 31, 1995
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Nobuyuki Fukazawa, Tsuneji Suzuki, Nobuya Kawauchi, Hironori Komatsu, Kengo Otsuka, Yuki Nakajima
  • Preparation process of aminoketones
    Patent number: 5194606
    Abstract: Novel aminoketones useful as central muscle relaxants and their preparation processes are disclosed. The disclosed processes are novel processes which do not use any heavy metal in view of the facts that their products are will be used as drugs and which require no complex purification step such as liberation of the aminoketones from their hydrochlorides or the like.
    Type: Grant
    Filed: July 23, 1991
    Date of Patent: March 16, 1993
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Akira Matsubara, Kazuya Sakai, Hideki Tanada, Hironori Komatsu
  • Preparation process of aminoketones
    Patent number: 5055585
    Abstract: Novel aminoketones useful as central muscle relaxants and their preparation processes are disclosed. The disclosed processes are novel processes which do not use any heavy metal in view of the facts that their products are will be used as drugs and which require no complex purification step such as liberation of the aminoketones from their hydrochlorides or the like.
    Type: Grant
    Filed: January 31, 1991
    Date of Patent: October 8, 1991
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Akira Matsubara, Kazuya Sakai, Hideki Tanada, Hironori Komatsu