Patents by Inventor Hironori Kurachi
Hironori Kurachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220380362Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: December 8, 2021Publication date: December 1, 2022Applicant: Japan Tobacco Inc.Inventors: Hisashi KAWASAKI, Hiroyuki ABE, Kazuhide HAYAKAWA, Tetsuya IIDA, Shinichi KIKUCHI, Takayuki YAMAGUCHI, Toyomichi NANAYAMA, Hironori KURACHI, Masahiro TAMARU, Yoshikazu HORI, Mitsuru TAKAHASHI, Takayuki YOSHIDA, Toshiyuki SAKAI
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Publication number: 20200109139Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: May 20, 2019Publication date: April 9, 2020Applicant: Japan Tobacco Inc.Inventors: Hisashi KAWASAKI, Hiroyuki ABE, Kazuhide HAYAKAWA, Tetsuya IIDA, Shinichi KIKUCHI, Takayuki YAMAGUCHI, Toyomichi NANAYAMA, Hironori KURACHI, Masahiro TAMARU, Yoshikazu HORI, Mitsuru TAKAHASHI, Takayuki YOSHIDA, Toshiyuki SAKAI
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Publication number: 20180273531Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: October 27, 2017Publication date: September 27, 2018Applicant: Japan Tobacco Inc.Inventors: Hisashi KAWASAKI, Hiroyuki ABE, Kazuhide HAYAKAWA, Tetsuya IIDA, Shinichi KIKUCHI, Takayuki YAMAGUCHI, Toyomichi NANAYAMA, Hironori KURACHI, Masahiro TAMARU, Yoshikazu HORI, Mitsuru TAKAHASHI, Takayuki YOSHIDA, Toshiyuki SAKAI
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Publication number: 20170029418Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: February 24, 2016Publication date: February 2, 2017Applicant: Japan Tobacco Inc.Inventors: Hisashi KAWASAKI, Hiroyuki ABE, Kazuhide HAYAKAWA, Tetsuya IIDA, Shinichi KIKUCHI, Takayuki YAMAGUCHI, Toyomichi NANAYAMA, Hironori KURACHI, Masahiro TAMARU, Yoshikazu HORI, Mitsuru TAKAHASHI, Takayuki YOSHIDA, Toshiyuki SAKAI
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Publication number: 20150183812Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: August 7, 2014Publication date: July 2, 2015Inventors: Hisashi KAWASAKI, Hiroyuki ABE, Kazuhide HAYAKAWA, Tetsuya IIDA, Shinichi KIKUCHI, Takayuki YAMAGUCHI, Toyomichi NANAYAMA, Hironori KURACHI, Masahiro TAMARU, Yoshikazu HORI, Mitsuru TAKAHASHI, Takayuki YOSHIDA, Toshiyuki SAKAI
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Patent number: 8835443Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: GrantFiled: November 25, 2009Date of Patent: September 16, 2014Assignee: Japan Tobacco Inc.Inventors: Hisashi Kawasaki, Hiroyuki Abe, Kazuhide Hayakawa, Tetsuya Iida, Shinichi Kikuchi, Takayuki Yamaguchi, Toyomichi Nanayama, Hironori Kurachi, Masahiro Tamaru, Yoshikazu Hori, Mitsuru Takahashi, Takayuki Yoshida, Toshiyuki Sakai
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Publication number: 20100240613Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: November 25, 2009Publication date: September 23, 2010Applicant: Japan Tobacco Inc.Inventors: Hisashi Kawasaki, Hiroyuki Abe, Kazuhide Hayakawa, Tetsuya Iida, Shinichi Kikuchi, Takayuki Yamaguchi, Toyomichi Nanayama, Hironori Kurachi, Masahiro Tamaru, Yoshikazu Hori, Mitsuru Takahashi, Takayuki Yoshida, Toshiyuki Sakai
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Publication number: 20080312228Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: March 21, 2008Publication date: December 18, 2008Applicant: Japan Tobacco Inc.Inventors: Hisashi Kawasaki, Hiroyuki Abe, Kazuhide Hayakawa, Tetsuya Iida, Shinichi Kikuchi, Takayuki Yamaguchi, Toyomichi Nanayama, Hironori Kurachi, Masahiro Tamaru, Yoshikazu Hori, Mitsuru Takahashi, Takayuki Yoshida, Toshiyuki Sakai
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Patent number: 7378423Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: GrantFiled: June 10, 2005Date of Patent: May 27, 2008Assignee: Japan Tobacco Inc.Inventors: Hisashi Kawasaki, Hiroyuki Abe, Kazuhide Hayakawa, Tetsuya Iida, Shinichi Kikuchi, Takayuki Yamaguchi, Toyomichi Nanayama, Hironori Kurachi, Masahiro Tamaru, Yoshikazu Hori, Mitsuru Takahashi, Takayuki Yoshida, Toshiyuki Sakai
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Publication number: 20060014768Abstract: The present invention relates to a pyrimidine compound or a pharmaceutically acceptable salt thereof represented by the following formula [I] wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like. In addition, the compound of the present invention can be a more effective antitumor agent when used in combination with other antitumor agents such as an alkylating agent or metabolism antagonist.Type: ApplicationFiled: June 10, 2005Publication date: January 19, 2006Applicant: Japan Tobacco Inc.Inventors: Hisashi Kawasaki, Hiroyuki Abe, Kazuhide Hayakawa, Tetsuya Iida, Shinichi Kikuchi, Takayuki Yamaguchi, Toyomichi Nanayama, Hironori Kurachi, Masahiro Tamaru, Yoshikazu Hori, Mitsuru Takahashi, Takayuki Yoshida, Toshiyuki Sakai